Master regulators or lineage-specifying? Changing views on CD4 T cell transcription factors (Q34305590)

1 August 2017

title

Master regulators or lineage-specifying? Changing views on CD4 T cell transcription factors (English)

1 reference

1 August 2017

Kenneth J Oestreich

1

1 reference

1 August 2017

Amy S Weinmann

series ordinal

2

1 reference

1 August 2017

publication date

12 October 2012

1 reference

Nature Reviews Immunology

1 August 2017

published in

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1 August 2017

volume

12

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1 August 2017

issue

11

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1 August 2017

page(s)

799-804

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Induction and molecular signature of pathogenic TH17 cells

1 August 2017

cites work

1 reference

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Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency

6 July 2018

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An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes

6 July 2018

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6 July 2018

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Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile

6 July 2018

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Helper T cell diversity and plasticity

6 July 2018

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STAT5 is a potent negative regulator of TFH cell differentiation

6 July 2018

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6 July 2018

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Early Th1 cell differentiation is marked by a Tfh cell-like transition

6 July 2018

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T-bet employs diverse regulatory mechanisms to repress transcription.

6 July 2018

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Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells

6 July 2018

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Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells.

6 July 2018

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An essential role of the transcription factor GATA-3 for the function of regulatory T cells

6 July 2018

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The BTB-ZF Family of Transcription Factors: Key Regulators of Lineage Commitment and Effector Function Development in the Immune System

6 July 2018

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6 July 2018

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Foxp3 follicular regulatory T cells control the germinal center response.

6 July 2018

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Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

6 July 2018

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6 July 2018

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6 July 2018

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The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns

6 July 2018

1 reference

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Genomic views of STAT function in CD4 T helper cell differentiation

6 July 2018

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Phenotypical and functional specialization of FOXP3 regulatory T cells

6 July 2018

1 reference

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Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

6 July 2018

1 reference

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Effector T cell plasticity: flexibility in the face of changing circumstances

6 July 2018

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Chromatin regulatory mechanisms in pluripotency

6 July 2018

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BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis

6 July 2018

1 reference

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Mechanisms underlying lineage commitment and plasticity of helper CD4 T cells

6 July 2018

1 reference

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Chromatin remodelling during development

6 July 2018

1 reference

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Decrease of Foxp3 Treg cell number and acquisition of effector cell phenotype during lethal infection

6 July 2018

1 reference

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CD4 regulatory T cells control TH17 responses in a Stat3-dependent manner.

6 July 2018

1 reference

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Bcl6 mediates the development of T follicular helper cells

6 July 2018

1 reference

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Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

6 July 2018

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Plasticity of CD4 T cell lineage differentiation.

6 July 2018

1 reference

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Epigenetic control of T-helper-cell differentiation

6 July 2018

1 reference

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Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4 T cells

6 July 2018

1 reference

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DC activated via dectin-1 convert Treg into IL-17 producers

6 July 2018

1 reference

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Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

Development, cytokine profile and function of human interleukin 17-producing helper T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

POZ for effect--POZ-ZF transcription factors in cancer and development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17 T helper cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

T-box genes in vertebrate development

6 July 2018

1 reference

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Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

Foxp3 programs the development and function of CD4 CD25 regulatory T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

Control of regulatory T cell development by the transcription factor Foxp3

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

Activated STAT4 has an essential role in Th1 differentiation and proliferation that is independent of its role in the maintenance of IL-12R beta 2 chain expression and signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

Regulation of interferon-gamma gene expression by nuclear factor of activated T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

A novel transcription factor, T-bet, directs Th1 lineage commitment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon gamma production from CD4( ) versus CD8( ) T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

6 July 2018

1 reference

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Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

Interferons direct Th2 cell reprogramming to generate a stable GATA-3( )T-bet( ) cell subset with combined Th2 and Th1 cell functions

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

In vivo generation of pathogen-specific Th1 cells in the absence of the IFN-gamma receptor.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3584691

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4 T cells

28 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038/NRI3321

GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet

31 March 2020

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Crossref

https://api.crossref.org/works/10.1038/NRI3321

Preferential role for NF-kappa B/Rel signaling in the type 1 but not type 2 T cell-dependent immune response in vivo

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23086326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRI3321

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference

1 August 2017

1 reference