The Thai Phase III HIV Type 1 Vaccine trial (RV144) regimen induces antibodies that target conserved regions within the V2 loop of gp120. (Q34303849)

1 August 2017

title

The Thai Phase III HIV Type 1 Vaccine trial (RV144) regimen induces antibodies that target conserved regions within the V2 loop of gp120. (English)

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1 August 2017

main subject

phase III clinical trial

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Jaranit Kaewkungwal

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John R. Mascola

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John R Mascola

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David C Montefiori

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Barton F Haynes

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Merlin L Robb

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Nelson L Michael

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Jeffrey R Currier

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Jerome H Kim

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Supachai Rerks-Ngarm

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Richard A Koup

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Raphael Gottardo

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Georgia D Tomaras

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Peter Gilbert

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Erik Billings

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Craig Magaret

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Viseth Ngauy

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Sorachai Nitayaphan

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Punnee Pitisuttithum

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Sanjay Gurunathan

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Nicos Karasavvas

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Susan Zolla-Pazner

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Charla Andrews

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Faruk Sinangil

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Sirinan Madnote

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Kelli Greene

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Timothy J Cardozo

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Jim Tartaglia

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MOPH TAVEG Collaboration

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MOPH TAVEG Collaboration

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Mangala Rao

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Constance Williams

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Robert T Bailer

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Duangnapa Arworn

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Xiaoying Shen

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Mike Jiang

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Robert Paris

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Hongmei Gao

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Mark S de Souza

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publication date

4 October 2012

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AIDS Research and Human Retroviruses

1 August 2017

published in

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volume

28

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issue

11

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page(s)

1444-1457

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Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7

1 August 2017

cites work

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Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen ALVAC-HIV (vCP1521) and AIDSVAX B/E: a post-hoc analysis of the Thai phase 3 efficacy trial RV 144.

6 July 2018

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Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials

6 July 2018

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The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope

6 July 2018

1 reference

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6 July 2018

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6 July 2018

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6 July 2018

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Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1

6 July 2018

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6 July 2018

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Mutation at a single position in the V2 domain of the HIV-1 envelope protein confers neutralization sensitivity to a highly neutralization-resistant virus

6 July 2018

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A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals

6 July 2018

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Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viral RNA levels

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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28 October 2018

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28 October 2018

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Identifiers

DOI

10.1089/AID.2012.0103

1 reference

1 August 2017

1 reference

1 August 2017

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