Troponin I phosphorylation in human myocardium in health and disease. (Q34302767)

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16 February 2020

title

Troponin I phosphorylation in human myocardium in health and disease (English)

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16 February 2020

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3

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16 February 2020

Jolanda van der Velden

series ordinal

4

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16 February 2020

author name string

P J M Wijnker

series ordinal

1

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16 February 2020

A M Murphy

series ordinal

2

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16 February 2020

publication date

1 October 2014

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Netherlands Heart Journal

16 February 2020

published in

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16 February 2020

volume

22

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16 February 2020

issue

10

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16 February 2020

page(s)

463-469

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Creative Commons Attribution 4.0 International

16 February 2020

copyright license

start time

9 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Phosphorylation of protein kinase C sites Ser42/44 decreases Ca(2 )-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Length-dependent activation is modulated by cardiac troponin I bisphosphorylation at Ser23 and Ser24 but not by Thr143 phosphorylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Integration of troponin I phosphorylation with cardiac regulatory networks

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Myofilament incorporation and contractile function after gene transfer of cardiac troponin I Ser43/45Ala

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

ACCF 2012 expert consensus document on practical clinical considerations in the interpretation of troponin elevations: a report of the American College of Cardiology Foundation task force on Clinical Expert Consensus Documents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Multiple Reaction Monitoring to Identify Site-Specific Troponin I Phosphorylated Residues in the Failing Human Heart

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Top-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Diastolic myofilament dysfunction in the failing human heart.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

More severe cellular phenotype in human idiopathic dilated cardiomyopathy compared to ischemic heart disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Why does troponin I have so many phosphorylation sites? Fact and fancy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Protein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca2 sensitivity in human myocardium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Cardiac myosin-binding protein C mutations and hypertrophic cardiomyopathy: haploinsufficiency, deranged phosphorylation, and cardiomyocyte dysfunction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Tropomyosin and the steric mechanism of muscle regulation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Unraveling molecular complexity of phosphorylated human cardiac troponin I by top down electron capture dissociation/electron transfer dissociation mass spectrometry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Functional effects of protein kinase C-mediated myofilament phosphorylation in human myocardium.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Length-dependent Ca(2 ) activation in cardiac muscle: some remaining questions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Calcium, thin filaments, and the integrative biology of cardiac contractility

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Protein kinase D is a novel mediator of cardiac troponin I phosphorylation and regulates myofilament function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Molecular and integrated biology of thin filament protein phosphorylation in heart muscle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Phosphorylation or glutamic acid substitution at protein kinase C sites on cardiac troponin I differentially depress myofilament tension and shortening velocity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Increased Ca2 -sensitivity of the contractile apparatus in end-stage human heart failure results from altered phosphorylation of contractile proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Cardiac excitation-contraction coupling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Effects of calcium, inorganic phosphate, and pH on isometric force in single skinned cardiomyocytes from donor and failing human hearts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Phosphorylation of both serine residues in cardiac troponin I is required to decrease the Ca2 affinity of cardiac troponin C.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Myoplasmic free calcium concentration reached during the twitch of an intact isolated cardiac cell and during calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned cardiac cell from the adult rat or rabbit ventricle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Identification of sites phosphorylated in bovine cardiac troponin I and troponin T by protein kinase C and comparative substrate activity of synthetic peptides containing the phosphorylation sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Sites phosphorylated in bovine cardiac troponin T and I. Characterization by 31P-NMR spectroscopy and phosphorylation by protein kinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Phosphorylation of troponin I and the inotropic effect of adrenaline in the perfused rabbit heart

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Phosphorylation of cardiac troponin by guanosine 3‘:5‘-monophosphate-dependent protein kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Calpain-1-sensitive myofibrillar proteins of the human myocardium.

6 July 2018

1 reference

https://api.crossref.org/works/10.1007/S12471-014-0590-4

Frequency- and afterload-dependent cardiac modulation in vivo by troponin I with constitutively active protein kinase A phosphorylation sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12471-014-0590-4

Myofilament length dependent activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12471-014-0590-4

Troponin I in the murine myocardium: influence on length-dependent activation and interfilament spacing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12471-014-0590-4

Cardiac troponin I threonine 144: role in myofilament length dependent activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12471-014-0590-4

The use of phosphate‐affinity SDS‐PAGE to measure the cardiac troponin I phosphorylation site distribution in human heart muscle

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Frank-Starling law and mass action calcium activation of the myofibril ATPase; comment on "de Tombe PP, Mateja RD, Tachampa K, Mou YA, Farman GP, Irving TC. Myofilament length dependent activation. J Mol Cell Cardiol 2010; 48: 851-8".

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188840

Recommendations for the use of cardiac troponin measurement in acute cardiac care

28 October 2018

1 reference

https://api.crossref.org/works/10.1007/S12471-014-0590-4

STUDIES ON STARLING'S LAW OF THE HEART. IX. THE EFFECTS OF IMPEDING VENOUS RETURN ON PERFORMANCE OF THE NORMAL AND FAILING HUMAN LEFT VENTRICLE

21 January 2018

1 reference

12 December 2020

Acute modulation of PP2a and troponin I phosphorylation in ventricular myocytes: studies with a novel PP2a peptide inhibitor

1 reference

12 December 2020

Exercise intolerance in patients with heart failure and preserved left ventricular systolic function: failure of the Frank-Starling mechanism

1 reference

12 December 2020

Attenuation of length dependence of calcium activation in myofilaments of transgenic mouse hearts expressing slow skeletal troponin I

1 reference

12 December 2020

The failing human heart is unable to use the Frank-Starling mechanism

1 reference

12 December 2020

Increased protein kinase C activity and expression of Ca2 -sensitive isoforms in the failing human heart

1 reference

12 December 2020

PKC-betaII sensitizes cardiac myofilaments to Ca2 by phosphorylating troponin I on threonine-144

1 reference

12 December 2020

10.1007/S12471-014-0590-4

Identifiers

DOI

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Dimensions Publication ID

16 February 2020

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16 February 2020

PubMed publication ID

25200323

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