Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations (Q34299378)

1 August 2017

title

Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations (English)

1 reference

1 August 2017

1 reference

Christina Kiel

1

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1 August 2017

Luis Serrano

series ordinal

2

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1 August 2017

publication date

6 May 2014

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Molecular Systems Biology

1 August 2017

published in

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1 August 2017

volume

10

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1 August 2017

page(s)

727

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Oncogenic RIT1 mutations in lung adenocarcinoma

1 August 2017

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Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling

6 July 2018

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6 July 2018

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Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

1 reference

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Germline gain-of-function mutations in SOS1 cause Noonan syndrome

6 July 2018

1 reference

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Expression of endogenous oncogenic V600EB-raf induces proliferation and developmental defects in mice and transformation of primary fibroblasts

6 July 2018

1 reference

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A quantitative protein interaction network for the ErbB receptors using protein microarrays

6 July 2018

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Noonan syndrome and related disorders: genetics and pathogenesis

6 July 2018

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Diverse biochemical properties of Shp2 mutants. Implications for disease phenotypes

6 July 2018

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6 July 2018

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Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades

6 July 2018

1 reference

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Structural analysis of autoinhibition in the Ras activator Son of sevenless

6 July 2018

1 reference

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Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

6 July 2018

1 reference

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6 July 2018

1 reference

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Tandem histone folds in the structure of the N-terminal segment of the ras activator Son of Sevenless

6 July 2018

1 reference

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6 July 2018

1 reference

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6 July 2018

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6 July 2018

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6 July 2018

1 reference

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Large-scale analysis of the human and mouse transcriptomes

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

1 reference

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Structural analysis of the GAP-related domain from neurofibromin and its implications

6 July 2018

1 reference

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Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2

6 July 2018

1 reference

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Crystal Structure of the Tyrosine Phosphatase SHP-2

6 July 2018

1 reference

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The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

6 July 2018

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The Shannon information entropy of protein sequences

6 July 2018

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6 July 2018

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The murine N-ras gene is not essential for growth and development

6 July 2018

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6 July 2018

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6 July 2018

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Analysis of Disease-Linked Rhodopsin Mutations Based on Structure, Function, and Protein Stability Calculations

6 July 2018

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Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders

28 October 2018

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Biochemical and functional characterization of germ line KRAS mutations

28 October 2018

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Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome

28 October 2018

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Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome

28 October 2018

1 reference

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A detailed thermodynamic analysis of ras/effector complex interfaces

28 October 2018

1 reference

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Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

28 October 2018

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28 October 2018

Identifiers

DOI

10.1002/MSB.20145092

1 reference

1 August 2017

1 reference

1 August 2017

1 reference