Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice (Q34299304)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739292 AND SRC:MED&resulttype=core&format=json

11 February 2020

title

Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739292 AND SRC:MED&resulttype=core&format=json

cerebral amyloid angiopathy

11 February 2020

main subject

1 reference

2

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11 February 2020

Radosveta Koldamova

8

1 reference

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11 February 2020

author name string

Iliya Lefterov

1

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11 February 2020

Andrea A Cronican

3

1 reference

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11 February 2020

Allison Fogg

4

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11 February 2020

Preslav Lefterov

5

1 reference

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11 February 2020

Ravindra Kodali

6

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11 February 2020

Ronald Wetzel

7

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11 February 2020

language of work or name

English

0 references

publication date

25 August 2010

1 reference

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Journal of Biological Chemistry

11 February 2020

published in

1 reference

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11 February 2020

volume

285

1 reference

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11 February 2020

issue

47

1 reference

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11 February 2020

page(s)

36945-36957

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739292 AND SRC:MED&resulttype=core&format=json

Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease.

11 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Fibrillar oligomers nucleate the oligomerization of monomeric amyloid beta but do not seed fibril formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Mitochondrial mechanisms in amyloid beta peptide-induced cerebrovascular degeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Human apolipoprotein A-I binds amyloid-beta and prevents Abeta-induced neurotoxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Structural classification of toxic amyloid oligomers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Cardiovascular risk factors and dementia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Expression profiling in APP23 mouse brain: inhibition of Abeta amyloidosis and inflammation in response to LXR agonist treatment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

HDL as a target in the treatment of atherosclerotic cardiovascular disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Apolipoprotein E isoforms and apolipoprotein AI protect from amyloid precursor protein carboxy terminal fragment-associated cytotoxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

ABCA1 and scavenger receptor class B, type I, are modulators of reverse sterol transport at an in vitro blood-brain barrier constituted of porcine brain capillary endothelial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Hypertension and hypercholesterolaemia as risk factors for Alzheimer's disease: potential for pharmacological intervention

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Cholesterol metabolism in the brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Elevated serum total and LDL cholesterol in very old patients with Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Differences in the Abeta40/Abeta42 ratio associated with cerebrospinal fluid lipoproteins as a function of apolipoprotein E genotype.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Decreased high-density lipoprotein cholesterol and serum apolipoprotein AI concentrations are highly correlated with the severity of Alzheimer's disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Progression of cerebral amyloid angiopathy: accumulation of amyloid-beta40 in affected vessels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Association of human, rat, and rabbit apolipoprotein E with ?-amyloid

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Role of calpain- and interleukin-1 beta converting enzyme-like proteases in the beta-amyloid-induced death of rat hippocampal neurons in culture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Apolipoprotein J and Alzheimer's amyloid beta solubility

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Synthesis of apolipoprotein A-1 in pig brain microvascular endothelial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Association of cardiovascular factors and Alzheimer's disease plasma amyloid-beta protein in subjective memory complainers

6 July 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.127738

CSF biomarker levels in early and late onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.127738

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.127738

Midlife vascular risk factors and late-life mild cognitive impairment: A population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.127738

Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.127738

Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.127738

Elevated low-density lipoprotein in Alzheimer's disease correlates with brain abeta 1-42 levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.127738

Memory deficits in APP23/Abca1 /- mice correlate with the level of Aβ oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.127738

The relation between apolipoprotein A-I and dementia: the Honolulu-Asia aging study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.127738

Influence of tertiary structure domain properties on the functionality of apolipoprotein A-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.127738

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.127738

Quantification of cerebral amyloid angiopathy and parenchymal amyloid plaques with Congo red histochemical stain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.127738

Low levels of serum apolipoprotein A I and A II in senile dementia.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978623

Relationships between cholesterol, apolipoprotein E polymorphism and dementia: a cross-sectional analysis from the PAQUID study

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20739292

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Kinetics and thermodynamics of amyloid assembly using a high-performance liquid chromatography-based sedimentation assay

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20739292

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Marked decrease of plasma apolipoprotein AI and AII in Japanese patients with late-onset non-familial Alzheimer's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20739292

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.127738

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739292 AND SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739292 AND SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

20739292

1 reference