BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues. (Q34290644)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22837753 AND SRC:MED&resulttype=core&format=json

9 February 2020

title

BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues (English)

1 reference

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G protein-coupled receptor

9 February 2020

main subject

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author

Damien Maurel

3

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9 February 2020

Jean-Philippe Pin

7

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9 February 2020

Thierry Durroux

8

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9 February 2020

author name string

Martin Cottet

1

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9 February 2020

Orestis Faklaris

2

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9 February 2020

Pauline Scholler

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9 February 2020

Etienne Doumazane

5

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9 February 2020

Eric Trinquet

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9 February 2020

publication date

23 July 2012

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Frontiers in Endocrinology

9 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22837753 AND SRC:MED&resulttype=core&format=json

9 February 2020

volume

3

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9 February 2020

page(s)

92

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Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy

9 February 2020

cites work

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Functional crosstalk and heteromerization of serotonin 5-HT2A and dopamine D2 receptors

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6 July 2018

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The oligomeric state sets GABA(B) receptor signalling efficacy

6 July 2018

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Full characterization of GPCR monomer-dimer dynamic equilibrium by single molecule imaging

6 July 2018

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G protein activation by serotonin type 4 receptor dimers: evidence that turning on two protomers is more efficient

6 July 2018

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Multiplexing of multicolor bioluminescence resonance energy transfer

6 July 2018

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Trans-activation between 7TM domains: implication in heterodimeric GABABreceptor activation

6 July 2018

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Class A GPCR heterodimers: evidence from binding studies

6 July 2018

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A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors.

6 July 2018

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Time-resolved luminescence resonance energy transfer imaging of protein-protein interactions in living cells

6 July 2018

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Time-resolved FRET between GPCR ligands reveals oligomers in native tissues.

6 July 2018

1 reference

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Site-specific, orthogonal labeling of proteins in intact cells with two small biarsenical fluorophores.

6 July 2018

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An in vivo demonstration of functional G protein-coupled receptor dimers

6 July 2018

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Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules

6 July 2018

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Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation.

6 July 2018

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Leukotriene BLT2 receptor monomers activate the G(i2) GTP-binding protein more efficiently than dimers

6 July 2018

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The asymmetric/symmetric activation of GPCR dimers as a possible mechanistic rationale for multiple signalling pathways.

6 July 2018

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Recent advances in bioluminescence resonance energy transfer technologies to study GPCR heteromerization

6 July 2018

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The role of dimerisation in the cellular trafficking of G-protein-coupled receptors

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Dopamine D2 receptors form higher order oligomers at physiological expression levels

6 July 2018

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6 July 2018

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Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization

6 July 2018

1 reference

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Identification of a serotonin/glutamate receptor complex implicated in psychosis

6 July 2018

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An engineered protein tag for multiprotein labeling in living cells

6 July 2018

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6 July 2018

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Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer

6 July 2018

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Activation of a dimeric metabotropic glutamate receptor by intersubunit rearrangement.

6 July 2018

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6 July 2018

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6 July 2018

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The alpha1b-adrenoceptor exists as a higher-order oligomer: effective oligomerization is required for receptor maturation, surface delivery, and function

6 July 2018

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Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light output

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Quantitative analysis of muscarinic acetylcholine receptor homo- and heterodimerization in live cells: regulation of receptor down-regulation by heterodimerization

6 July 2018

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On the use of nonfluorescent dye labeled ligands in FRET-based receptor binding studies

6 July 2018

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6 July 2018

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Monomeric G-protein-coupled receptor as a functional unit

6 July 2018

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6 July 2018

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The CXCR1 and CXCR2 receptors form constitutive homo- and heterodimers selectively and with equal apparent affinities

6 July 2018

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Principles: a model for the allosteric interactions between ligand binding sites within a dimeric GPCR.

6 July 2018

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Engineering substrate specificity of O6-alkylguanine-DNA alkyltransferase for specific protein labeling in living cells

6 July 2018

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Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity

6 July 2018

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Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.

6 July 2018

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Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR

6 July 2018

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Closed state of both binding domains of homodimeric mGlu receptors is required for full activity.

6 July 2018

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Agonist-dependent dissociation of human somatostatin receptor 2 dimers: a role in receptor trafficking

6 July 2018

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Labeling of fusion proteins with synthetic fluorophores in live cells

6 July 2018

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Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting

6 July 2018

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Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns

6 July 2018

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Roles of G-protein-coupled receptor dimerization

6 July 2018

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Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors

6 July 2018

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Directed evolution of O6-alkylguanine-DNA alkyltransferase for efficient labeling of fusion proteins with small molecules in vivo

6 July 2018

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Fluorescence resonance energy transfer to probe human M1 muscarinic receptor structure and drug binding properties

6 July 2018

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Rod cyclic nucleotide-gated channels have a stoichiometry of three CNGA1 subunits and one CNGB1 subunit

6 July 2018

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The use of resonance energy transfer in high-throughput screening: BRET versus FRET.

6 July 2018

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Time resolved amplification of cryptate emission: a versatile technology to trace biomolecular interactions

6 July 2018

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Principles and biophysical applications of lanthanide-based probes

6 July 2018

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G-protein-coupled receptor dimerization: modulation of receptor function.

6 July 2018

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Ligand binding to somatostatin receptors induces receptor-specific oligomer formation in live cells

6 July 2018

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A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor

6 July 2018

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6 July 2018

1 reference

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C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors.

6 July 2018

1 reference

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Functional significance of oligomerization of G-protein-coupled receptors.

6 July 2018

1 reference

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Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)

6 July 2018

1 reference

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G-protein-coupled receptor heterodimerization modulates receptor function

6 July 2018

1 reference

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Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding

6 July 2018

1 reference

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GABA(B)-receptor subtypes assemble into functional heteromeric complexes.

6 July 2018

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Dopamine D2 receptor dimers and receptor-blocking peptides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Probing molecular interactions with homogeneous techniques based on rare earth cryptates and fluorescence energy transfer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Heterocomplex formation of 5-HT2A-mGlu2 and its relevance for cellular signaling cascades

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Semisynthesis of fluorescent metabolite sensors on cell surfaces.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Time resolved FRET strategy with fluorescent ligands to analyze receptor interactions in native tissues: application to GPCR oligomerization.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

A Fluorescent Ligand-Binding Alternative Using Tag-lite® Technology

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Selective cross-linking of interacting proteins using self-labeling tags

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Semisynthetic fluorescent sensor proteins based on self-labeling protein tags.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Toward efficient drug screening by homogeneous assays based on the development of new fluorescent vasopressin and oxytocin receptor ligands.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Heterodimeric adenosine receptors: a device to regulate neurotransmitter release.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

D-myo-inositol 1-phosphate as a surrogate of D-myo-inositol 1,4,5-tris phosphate to monitor G protein-coupled receptor activation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Probing the existence of G protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

HaloTag protein-mediated site-specific conjugation of bioluminescent proteins to quantum dots.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Multiple interactions between transmembrane helices generate the oligomeric alpha1b-adrenoceptor.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

High-affinity interactions between human alpha1A-adrenoceptor C-terminal splice variants produce homo- and heterodimers but do not generate the alpha1L-adrenoceptor.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Domain swapping in the human histamine H1 receptor

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Cell surface detection of membrane protein interaction with homogeneous time-resolved fluorescence resonance energy transfer technology

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

A general method for the covalent labeling of fusion proteins with small molecules in vivo

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Dopamine D2 receptor dimer formation: evidence from ligand binding

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Dimerization of the delta opioid receptor: implication for a role in receptor internalization

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Guanine nucleotide regulation of a mammalian myocardial muscarinic receptor system. Evidence for homo- and heterotropic cooperativity in ligand binding analyzed by computer-assisted curve fitting.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Oxytocin and Vasopressin V1a and V2 Receptors Form Constitutive Homo- and Heterodimers during Biosynthesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401989

Differential association modes of the thrombin receptor PAR1 with Galphai1, Galpha12, and beta-arrestin 1

28 October 2018

1 reference

12 December 2020

Cooperativity Manifest in the Binding Properties of Purified Cardiac Muscarinic Receptors

1 reference

12 December 2020

Rhodopsin dimers in native disc membranes

1 reference

12 December 2020

Coupling of agonist binding to effector domain activation in metabotropic glutamate-like receptors

1 reference

12 December 2020

Bioluminescence resonance energy transfer (BRET) for the real-time detection of protein-protein interactions

1 reference

12 December 2020

Fluorescent pseudo-peptide linear vasopressin antagonists: design, synthesis, and applications

1 reference

12 December 2020

Luteinizing hormone receptors are self-associated in the plasma membrane

1 reference

12 December 2020

Oligomerization of recombinant and endogenously expressed human histamine H(4) receptors

1 reference

12 December 2020

Metabotropic glutamate receptor 5 is a disulfide-linked dimer

1 reference

12 December 2020

Mapping the agonist-binding site of GABAB type 1 subunit sheds light on the activation process of GABAB receptors

1 reference

12 December 2020

Identifiers

DOI

10.3389/FENDO.2012.00092

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22837753 AND SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22837753 AND SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

22837753

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22837753 AND SRC:MED&resulttype=core&format=json