Etiology of Crohn's disease: many roads lead to autophagy (Q34288268)

1 August 2017

title

Etiology of Crohn's disease: many roads lead to autophagy (English)

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1 August 2017

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3

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Arlette Darfeuille-Michaud

1 August 2017

series ordinal

4

object named as

Arlette Darfeuille-Michaud

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Pierre Lapaquette

object named as

Pierre Lapaquette

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1

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Patrick Brest

object named as

Patrick Brest

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2

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publication date

14 July 2012

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Journal of Molecular Medicine

1 August 2017

published in

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1 August 2017

volume

90

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1 August 2017

issue

9

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1 August 2017

page(s)

987-996

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New global map of Crohn's disease: Genetic, environmental, and socioeconomic correlations.

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

The evolving epidemiology of inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Clustering in time of familial IBD separates ulcerative colitis from Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Epidemiology of inflammatory bowel disease in a German twin cohort: results of a nationwide study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Genetics and pathogenesis of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

The role of bacteria and pattern-recognition receptors in Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Pathogenic agents in inflammatory bowel diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in Crohn's disease involving the ileum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Escherichia coli isolated from a Crohn's disease patient adheres, invades, and induces inflammatory responses in polarized intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Molecular diversity of Escherichia coli in the human gut: new ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Invasive Escherichia coli are a feature of Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Increased short- and long-term risk of inflammatory bowel disease after salmonella or campylobacter gastroenteritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Revisiting the host as a growth medium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Overview of macroautophagy regulation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

The roles of intracellular protein-degradation pathways in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Excess peroxisomes are degraded by autophagic machinery in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

21 January 2018

Autophagy in infection

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Autophagy and the Integrated Stress Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Autophagy and Crohn's disease: at the crossroads of infection, inflammation, immunity, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Defects in autophagy favour adherent-invasive Escherichia coli persistence within macrophages leading to increased pro-inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Death and resurrection of the human IRGM gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Human IRGM induces autophagy to eliminate intracellular mycobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Risk predisposition for Crohn disease: a "ménage à trois" combining IRGM allele, miRNA and xenophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

IRGM is a common target of RNA viruses that subvert the autophagy network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Everolimus for refractory Crohn's disease: a case report

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Use of sirolimus (rapamycin) to treat refractory Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Small molecule regulators of autophagy identified by an image-based high-throughput screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Genetic variants in autophagy-related genes and granuloma formation in a cohort of surgically treated Crohn's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Specificities of the fecal microbiota in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00109-012-0934-8

Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease

21 January 2018

1 reference

12 December 2020

Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

1 reference

12 December 2020

Toll-like receptor gene polymorphisms and susceptibility to inflammatory bowel disease in Chinese Han and Caucasian populations

1 reference

12 December 2020

Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum

1 reference

12 December 2020

10.1007/S00109-012-0934-8

Identifiers

DOI

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Dimensions Publication ID

1 August 2017

1042148101

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