Cancer chromosomal instability: therapeutic and diagnostic challenges (Q34275721)

1 August 2017

title

Cancer chromosomal instability: therapeutic and diagnostic challenges (English)

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1 August 2017

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Nicholas McGranahan

1

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Charles Swanton

object named as

Charles Swanton

5

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author name string

Rebecca A Burrell

2

1 reference

1 August 2017

David Endesfelder

3

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1 August 2017

Marco R Novelli

4

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1 August 2017

publication date

1 June 2012

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1 August 2017

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1 August 2017

volume

13

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1 August 2017

issue

6

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1 August 2017

page(s)

528-538

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

1 August 2017

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6 July 2018

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6 July 2018

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The relationship between the presence of chromosomal instability and prognosis of squamous cell carcinoma of the lung: fluorescence in situ hybridization analysis of paraffin-embedded tissue from 47 Korean patients

6 July 2018

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Prognostic utility of chromosomal instability detected by fluorescence in situ hybridization in fine-needle aspirates from oral squamous cell carcinomas

6 July 2018

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6 July 2018

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Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Chromosomal instability: a composite phenotype that influences sensitivity to chemotherapy

6 July 2018

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Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group

6 July 2018

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Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

6 July 2018

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A mechanism linking extra centrosomes to chromosomal instability

6 July 2018

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Chromosomal instability determines taxane response

6 July 2018

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High hyperdiploid childhood acute lymphoblastic leukemia

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Overexpression of Separase induces aneuploidy and mammary tumorigenesis

6 July 2018

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Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

6 July 2018

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Human Sgo1 downregulation leads to chromosomal instability in colorectal cancer

6 July 2018

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Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Structural and numerical chromosome changes in colon cancer develop through telomere-mediated anaphase bridges, not through mitotic multipolarity

6 July 2018

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Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B.

6 July 2018

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6 July 2018

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Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

6 July 2018

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The optimal rate of chromosome loss for the inactivation of tumor suppressor genes in cancer

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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The mutational meltdown in asexual populations

6 July 2018

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Chromosomal instability is a risk factor for poor prognosis of adenocarcinoma of the lung: Fluorescence in situ hybridization analysis of paraffin-embedded tissue from Korean patients

6 July 2018

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A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers

21 January 2018

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Aneuploidy acts both oncogenically and as a tumor suppressor

21 January 2018

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Overexpression of the mitotic checkpoint genes BUB1, BUBR1, and BUB3 in gastric cancer--association with tumour cell proliferation.

21 January 2018

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Telomere dysfunction and the initiation of genome instability.

21 January 2018

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Are aneuploidy and chromosome breakage caused by a CINgle mechanism?

21 January 2018

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Patterns and incidence of chromosomal instability and their prognostic relevance in breast cancer subtypes.

21 January 2018

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Improved grading of breast adenocarcinomas based on genomic instability

21 January 2018

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Chromosomal and genetic imbalances in synovial sarcoma detected by conventional and microarray comparative genomic hybridization.

21 January 2018

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Targeting aneuploidy for cancer therapy.

21 January 2018

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Significance of MAD2 expression to mitotic checkpoint control in ovarian cancer cells.

21 January 2018

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Genome-wide genetic analysis of polyploidy in yeast

28 October 2018

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https://api.crossref.org/works/10.1038/EMBOR.2012.61

Whole chromosome loss is promoted by telomere dysfunction in primary cells

21 January 2018

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12 December 2020

Chromosome instability in resection margins predicts recurrence of oral squamous cell carcinoma

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12 December 2020

Genome-wide single-nucleotide polymorphism arrays in endometrial carcinomas associate extensive chromosomal instability with poor prognosis and unveil frequent chromosomal imbalances involved in the PI3-kinase pathway

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12 December 2020

Chromosomal instability detected by fluorescence in situ hybridization in Japanese breast cancer patients

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12 December 2020

Chromosomal instability detected by fluorescence in situ hybridization in surgical specimens of non-small cell lung cancer is associated with poor survival

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12 December 2020

Chromosomal instability predicts metastatic disease in patients with insulinomas

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Identifiers

DOI

10.1038/EMBOR.2012.61

1 reference

1 August 2017

1 reference

1 August 2017

1 reference