Cotranscriptionally Formed DNA:RNA Hybrids Mediate Transcription Elongation Impairment and Transcription-Associated Recombination (Q34267573)

1 August 2017

title

Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination (English)

1 reference

1 August 2017

Cotranscriptionally Formed DNA:RNA Hybrids Mediate Transcription Elongation Impairment and Transcription-Associated Recombination (English)

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2003.08.010

18 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2003.08.010

18 March 2024

Pablo Huertas

1

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Andrés Aguilera

object named as

Andrés Aguilera

2

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language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14527416

18 March 2024

publication date

1 September 2003

1 reference

full work available at URL

1 August 2017

http://www.cell.com/article/S1097276503003198/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:14527416

https://api.elsevier.com/content/article/PII:S1097276503003198?httpAccept=text/xml

18 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2003.08.010

https://api.elsevier.com/content/article/PII:S1097276503003198?httpAccept=text/plain

18 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2003.08.010

18 March 2024

1 reference

1 August 2017

volume

12

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1 August 2017

issue

3

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1 August 2017

page(s)

711-721

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The connection between transcription and genomic instability

1 August 2017

cites work

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HPR1, a novel yeast gene that prevents intrachromosomal excision recombination, shows carboxy-terminal homology to the Saccharomyces cerevisiae TOP1 gene.

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The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability

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A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae

18 March 2024

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Hpr1 is preferentially required for transcription of either long or G C-rich DNA sequences in Saccharomyces cerevisiae.

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High-copy-number expression of Sub2p, a member of the RNA helicase superfamily, suppresses hpr1-mediated genomic instability

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Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism

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RNase H overproduction corrects a defect at the level of transcription elongation during rRNA synthesis in the absence of DNA topoisomerase I in Escherichia coli

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Transcription promotes recA-independent recombination mediated by DNA-dependent RNA polymerase in Escherichia coli

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The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability

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DNA double-strand breaks: signaling, repair and the cancer connection

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Transcription through a simple DNA repeat blocks replication elongation

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Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradation

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Differential intrachromosomal hyper-recombination phenotype of spt4 and spt6 mutants of S. cerevisiae.

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Escherichia coli DNA topoisomerase I inhibits R-loop formation by relaxing transcription-induced negative supercoiling.

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DNA damage processing defects and disease

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Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds

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Saccharomyces cerevisiae chromatin-assembly factors that act during DNA replication function in the maintenance of genome stability.

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Transcription enhances intrachromosomal homologous recombination in mammalian cells

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Switch region of immunoglobulin Cmu gene is composed of simple tandem repetitive sequences

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A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination.

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Recombination between DNA repeats in yeast hpr1delta cells is linked to transcription elongation

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RuvAB acts at arrested replication forks

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TREX is a conserved complex coupling transcription with messenger RNA export

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Elevated recombination rates in transcriptionally active DNA

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Recombination-stimulating sequences in yeast ribosomal DNA correspond to sequences regulating transcription by RNA polymerase I

18 March 2024

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Rad52-independent accumulation of joint circular minichromosomes during S phase in Saccharomyces cerevisiae

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R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

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Stable mRNP formation and export require cotranscriptional recruitment of the mRNA export factors Yra1p and Sub2p by Hpr1p

18 March 2024

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HPR1 encodes a global positive regulator of transcription in Saccharomyces cerevisiae

18 March 2024

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18 March 2024

Identifiers

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1 August 2017

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