Centrosome abnormalities, genomic instability and carcinogenic progression (Q34244325)

31 July 2017

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title

Centrosome abnormalities, genomic instability and carcinogenic progression (English)

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31 July 2017

S Duensing

1

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31 July 2017

K Münger

series ordinal

2

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31 July 2017

language of work or name

English

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publication date

1 January 2001

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Biochimica et Biophysica Acta

31 July 2017

published in

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31 July 2017

volume

1471

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31 July 2017

issue

2

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31 July 2017

page(s)

M81-8

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

31 July 2017

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7 January 2021

Microtubule organizing centers

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

The centrosome and cellular organization

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Cell division: The renaissance of the centriole

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

The coordination of centrosome reproduction with nuclear events of the cell cycle in the sea urchin zygote

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Cyclin-dependent kinase control of centrosome duplication

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A.

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Association of human SCF(SKP2) subunit p19(SKP1) with interphase centrosomes and mitotic spindle poles

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Activity and regulation of the centrosome-associated proteasome

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

γ-Tubulin is a highly conserved component of the centrosome

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Pericentrin, a highly conserved centrosome protein involved in microtubule organization

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Centriole number and the reproductive capacity of spindle poles

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Microsurgical removal of centrosomes blocks cell reproduction and centriole generation in BSC-1 cells

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Centriole disassembly in vivo and its effect on centrosome structure and function in vertebrate cells

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Centrosome-independent mitotic spindle formation in vertebrates

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Journey to the centre of the cell

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Polarity and nucleation of microtubules in polarized epithelial cells

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

DNA-replication/DNA-damage-dependent centrosome inactivation in Drosophila embryos

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

The respective contributions of the mother and daughter centrioles to centrosome activity and behavior in vertebrate cells

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Sid4p is required to localize components of the septation initiation pathway to the spindle pole body in fission yeast.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

The role of the sid1p kinase and cdc14p in regulating the onset of cytokinesis in fission yeast

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Molecular components of the centrosome

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Alzheimer Presenilins in the Nuclear Membrane, Interphase Kinetochores, and Centrosomes Suggest a Role in Chromosome Segregation

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Centrosome proteins: a major class of autoantigens in scleroderma

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Vaccinia virus infection disrupts microtubule organization and centrosome function.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Multiple centrosome formation induced by the expression of Vpr gene of human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Anticentriolar autoantibodies in children with central nervous system manifestations of Mycoplasma pneumoniae infection

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Altered centrosome structure is associated with abnormal mitoses in human breast tumors

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Centrosome abnormalities in human carcinomas of the gallbladder and intrahepatic and extrahepatic bile ducts

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Centrosome amplification as a possible mechanism for numerical chromosome aberrations in cerebral primitive neuroectodermal tumors with TP53 mutations

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

The centrosome--a tiny organelle with big potential

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Abnormal centrosome amplification in the absence of p53.

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Genomic instability in Gadd45a-deficient mice

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

MAPK mediates RAS-induced chromosome instability

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Induction of chromosome abnormalities in mouse and human epidermal keratinocytes by the human papillomavirus type 16 E7 oncogene

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Long-term genome stability and minimal genotypic and phenotypic alterations in HPV16 E7-, but not E6-, immortalized human uroepithelial cells

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Specific chromosomal imbalances in human papillomavirus-transfected cells during progression toward immortality

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Viruses in human cancers

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Human Papillomavirus Type 16 and Early Cervical Neoplasia

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Disruption of the G 1 /S Transition in Human Papillomavirus Type 16 E7-Expressing Human Cells Is Associated with Altered Regulation of Cyclin E

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Deregulated cyclin E induces chromosome instability

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin E overexpression

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

The human papillomavirus-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Formation of the tetraploid intermediate is associated with the development of cells with more than four centrioles in the elastase-simian virus 40 tumor antigen transgenic mouse model of pancreatic cancer.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Genetic instabilities in human cancers

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Increased tumor proliferation and genomic instability without decreased apoptosis in MMTV-ras mice deficient in p53

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Both viral (adenovirus E1B) and cellular (hsp 70, p53) components interact with centrosomes.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Translocation of the retinoblastoma gene product during mitosis

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Cell cycle independent interaction of CDC2 with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Association of 14-3-3 proteins with centrosomes

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https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

BRCA1 is associated with the centrosome during mitosis.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Differential subcellular localization of protein phosphatase-1 alpha, gamma1, and delta isoforms during both interphase and mitosis in mammalian cells

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

When overexpressed, a novel centrosomal protein, RanBPM, causes ectopic microtubule nucleation similar to gamma-tubulin

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Cell cycle-dependent localization of casein kinase I to mitotic spindles.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Casein kinase II is a predominantly nuclear enzyme

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Cyclic-AMP-dependent protein kinase type II is associated with the Golgi complex and with centrosomes

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Heterogeneous distribution of the cAMP receptor protein RII in the nervous system: evidence for its intracellular accumulation on microtubules, microtubule-organizing centers, and in the area of the Golgi complex

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Protein kinase C-theta is specifically localized on centrosomes and kinetochores in mitotic cells.

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

Association of calmodulin with cytoskeletal structures at different stages of HeLa cell division, visualized by a calmodulin-EGFP fusion protein

1 reference

https://api.crossref.org/works/10.1016/S0304-419X(00)50025-1

7 January 2021

10.1016/S0304-419X(00)00025-1

Identifiers

DOI

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31 July 2017

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