Targeting leukocyte migration and adhesion in Crohn's disease and ulcerative colitis (Q34243433)

31 July 2017

title

Targeting leukocyte migration and adhesion in Crohn's disease and ulcerative colitis (English)

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31 July 2017

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Saskia Thomas

1

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31 July 2017

Daniel C Baumgart

series ordinal

2

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31 July 2017

language of work or name

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20 December 2011

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31 July 2017

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31 July 2017

volume

20

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31 July 2017

issue

1

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31 July 2017

page(s)

1-18

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Tissue-tropic effector T cells: generation and targeting opportunities

31 July 2017

cites work

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Lymphocyte homing and homeostasis

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The many roles of chemokines and chemokine receptors in inflammation

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Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs

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Treatment of active Crohn's disease with MLN0002, a humanized antibody to the alpha4beta7 integrin

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Chemokines and disease

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Natalizumab for active Crohn's disease

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Therapeutic anti-integrin (alpha4 and alphaL) monoclonal antibodies: two-edged swords?

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A randomized placebo-controlled trial of a humanized monoclonal antibody to alpha4 integrin in active Crohn's disease.

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Heteronuclear (1H, 13C, 15N) NMR assignments and solution structure of the monocyte chemoattractant protein-1 (MCP-1) dimer

21 January 2018

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Integrins: bidirectional, allosteric signaling machines

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The yin and yang of intestinal epithelial cells in controlling dendritic cell function

21 January 2018

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Small intestinal CD103 dendritic cells display unique functional properties that are conserved between mice and humans.

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Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis

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Expression of the mucosal lymphocyte integrin alphaEbeta7 and its ligand E-cadherin in salivary glands of patients with Sjögren's syndrome

21 January 2018

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Chemokines in lymphocyte trafficking and intestinal immunity

21 January 2018

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Progressive multifocal leukoencephalopathy in a patient treated with natalizumab

21 January 2018

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Tumor necrosis factor-α monoclonal antibodies in the treatment of inflammatory bowel disease: clinical practice pharmacology

21 January 2018

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The role of beta7 integrins in CD8 T cell trafficking during an antiviral immune response

21 January 2018

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Chemokines — Chemotactic Cytokines That Mediate Inflammation

21 January 2018

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Cell-cell interactions: leukocyte-endothelial interactions

21 January 2018

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Bioavailability and therapeutic activity of alicaforsen (ISIS 2302) administered as a rectal retention enema to subjects with active ulcerative colitis

21 January 2018

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Homing imprinting and immunomodulation in the gut: role of dendritic cells and retinoids

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Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease

21 January 2018

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A novel chemokine ligand for CCR10 and CCR3 expressed by epithelial cells in mucosal tissues

21 January 2018

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Leukocyte-endothelial cell interactions: molecular mechanisms and implications in gastrointestinal disease

21 January 2018

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Leukocyte-endothelial cell adhesion: avenues for therapeutic intervention

21 January 2018

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Up-regulation of alphaEbeta7, a novel integrin adhesion molecule, on T cells from systemic lupus erythematosus patients with specific epithelial involvement

21 January 2018

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The role of heparan sulphate in inflammation

21 January 2018

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Ligand binding to integrins

21 January 2018

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Pharmacological characterization of PF-00547659, an anti-human MAdCAM monoclonal antibody

21 January 2018

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Antibody blockade of CCL25/CCR9 ameliorates early but not late chronic murine ileitis

21 January 2018

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Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells

21 January 2018

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Lymphocyte homing to the gut: attraction, adhesion, and commitment

21 January 2018

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Integrin alpha E(CD103)beta 7 influences cellular shape and motility in a ligand-dependent fashion

21 January 2018

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Absence of efficacy of subcutaneous antisense ICAM-1 treatment of chronic active Crohn's disease

21 January 2018

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Therapeutic antagonists and conformational regulation of integrin function

21 January 2018

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The binding specificity and selective antagonism of vedolizumab, an anti-alpha4beta7 integrin therapeutic antibody in development for inflammatory bowel diseases

21 January 2018

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A humanized monoclonal antibody targeting the β7 integrin selectively blocks intestinal homing of T lymphocytes

21 January 2018

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Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis

21 January 2018

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Natalizumab for the treatment of active Crohn's disease: results of the ENCORE Trial

21 January 2018

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https://api.crossref.org/works/10.1007/S10787-011-0104-6

Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10787-011-0104-6

Function and interactions of integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10787-011-0104-6

A phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10787-011-0104-6

T-Cell Function and Migration — Two Sides of the Same Coin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10787-011-0104-6

A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10787-011-0104-6

Double blind, placebo controlled trial of the remission inducing and steroid sparing properties of an ICAM-1 antisense oligodeoxynucleotide, alicaforsen (ISIS 2302), in active steroid dependent Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10787-011-0104-6

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10787-011-0104-6

Chemokines: a new classification system and their role in immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10787-011-0104-6

The monoclonal anti-VLA-4 antibody natalizumab mobilizes CD34 hematopoietic progenitor cells in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10787-011-0104-6

VCAM-1 and ICAM-1 mediate leukocyte-endothelial cell adhesion in rat experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10787-011-0104-6

α4Integrins as Therapeutic Targets in Autoimmune Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10787-011-0104-6

A novel, orally active alpha 4 integrin antagonist, AJM300 prevents the development of experimental colitis induced by adoptive transfer of IL-10 deficient CD4( ) T cells in mice

21 January 2018

1 reference

12 December 2020

Rapid resolution of chronic colitis in the cotton-top tamarin with an antibody to a gut-homing integrin alpha 4 beta 7

1 reference

12 December 2020

Migration of leukocytes through the vessel wall and beyond

1 reference

12 December 2020

Regional differences in constitutive and induced ICAM-1 expression in vivo

1 reference

12 December 2020

Amelioration of murine experimental colitis by inhibition of mucosal addressin cell adhesion molecule-1

1 reference

12 December 2020

The molecular basis and specificity of integrin-ligand interactions

1 reference

12 December 2020

Chemokines: signal lamps for trafficking of T and B cells for development and effector function.

1 reference

12 December 2020

A pilot study of treatment of active ulcerative colitis with natalizumab, a humanized monoclonal antibody to alpha-4 integrin

1 reference

12 December 2020

Phase I safety and pharmacokinetic profile of an intercellular adhesion molecule-1 antisense oligodeoxynucleotide (ISIS 2302)

1 reference

12 December 2020

GSK-1605786, a selective small-molecule antagonist of the CCR9 chemokine receptor for the treatment of Crohn's disease.

1 reference

12 December 2020

Lymphocyte activation antigens. I. A monoclonal antibody, anti-Act I, defines a new late lymphocyte activation antigen

1 reference

12 December 2020

Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue

1 reference

12 December 2020

Cytokine-induced VCAM-1 and ICAM-1 expression in different organs of the mouse.

1 reference

12 December 2020

Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response

1 reference

12 December 2020

Altered expression of alpha E beta 7 integrin on intra-epithelial and lamina propria lymphocytes in patients with Crohn's disease

1 reference

12 December 2020

Adhesion molecule expression on vascular endothelium and nitroblue tetrazolium reducing activity in human colonic mucosa

1 reference

12 December 2020

VCAM-1, but Not ICAM-1 or MAdCAM-1, Immunoblockade Ameliorates DSS-Induced Colitis in Mice

1 reference

12 December 2020

Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4 , CD45RBhigh T cells to SCID recipients

1 reference

12 December 2020

Safety and efficacy of two dose formulations of alicaforsen enema compared with mesalazine enema for treatment of mild to moderate left-sided ulcerative colitis: a randomized, double-blind, active-controlled trial

1 reference

12 December 2020

CD103 is a marker for alloantigen-induced regulatory CD8 T cells

1 reference

12 December 2020

Characterization of the mucosal cell-mediated immune response in IL-2 knockout mice before and after the onset of colitis

1 reference

12 December 2020

Administration of mAb against alpha E beta 7 prevents and ameliorates immunization-induced colitis in IL-2-/- mice

1 reference

12 December 2020

The Role of α4-Integrin in T Lymphocyte Migration Into the Inflamed and Noninflamed Central Nervous System

1 reference

12 December 2020

1 reference

12 December 2020

The role of alpha E beta 7 integrin (CD103) and E-cadherin in epidermotropism in cutaneous T-cell lymphoma

1 reference

12 December 2020

The mucosal addressin cell adhesion molecule antibody PF-00547,659 in ulcerative colitis: a randomised study

1 reference

12 December 2020

Natalizumab Induction and Maintenance Therapy for Crohn's Disease

1 reference

12 December 2020

Selective expression of integrin alpha 4 beta 7 on a subset of human CD4 memory T cells with Hallmarks of gut-trophism.

1 reference

12 December 2020

Up-regulation of E-selectin and intercellular adhesion molecule-1 differs between Crohn's disease and ulcerative colitis

1 reference

12 December 2020

Expression of vascular adhesion molecules in inflammatory bowel disease

1 reference

12 December 2020

Characterization of CCX282-B, an orally bioavailable antagonist of the CCR9 chemokine receptor, for treatment of inflammatory bowel disease

1 reference

12 December 2020

Proteasome inhibition attenuates nitric oxide synthase expression, VCAM-1 transcription and the development of chronic colitis

1 reference

12 December 2020

Novel approaches to treating inflammatory bowel disease: targeting alpha-4 integrin

1 reference

12 December 2020

[Cellular adherence and chronic inflammatory bowel diseases]

1 reference

12 December 2020

Efficacy and safety of tumor necrosis factor antagonists in Crohn's disease: meta-analysis of placebo-controlled trials

1 reference

12 December 2020

Expression of the mucosal lymphocyte integrin alpha E beta 7 and its ligand E-cadherin in the synovium of patients with rheumatoid arthritis

1 reference

12 December 2020

Cytokine and endothelial cell adhesion molecule expression in interleukin-10-deficient mice

1 reference

12 December 2020

Monoclonal antibodies specific for beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) reduce inflammation in the colon of scid mice reconstituted with CD45RBhigh CD4 T cells

1 reference

12 December 2020

Differential expression of alpha E beta 7 integrins on bronchoalveolar lavage T lymphocyte subsets: regulation by alpha 4 beta 1-integrin crosslinking and TGF-beta

1 reference

12 December 2020

In situ expression of the cell adhesion molecules in inflammatory bowel disease. Evidence of immunologic activation of vascular endothelial cells

1 reference

12 December 2020

Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25 as well as CD25- regulatory T cells

1 reference

12 December 2020

Progressive multifocal leukoencephalopathy associated with efalizumab use in psoriasis patients

1 reference

12 December 2020

Neutrophils generate oxygen free radicals in rat mesenteric microcirculation after abdominal irradiation

1 reference

12 December 2020

Structure-function analysis of the integrin beta 7 subunit: identification of domains involved in adhesion to MAdCAM-1

1 reference

12 December 2020

10.1007/S10787-011-0104-6

Identifiers

DOI

1 reference

release_m4k72qsn4rblflc7qkyawjjqbi

31 July 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/m4k72qsn4rblflc7qkyawjjqbi

24 November 2022

mapped directly with Wikidata item

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