Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor. (Q34232074)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20716524 AND SRC:MED&resulttype=core&format=json

10 February 2020

title

Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20716524 AND SRC:MED&resulttype=core&format=json

10 February 2020

main subject

transmembrane protein

0 references

author

Michel Bouvier

5

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10 February 2020

Joe B Blumer

6

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10 February 2020

Stephen M. Lanier

7

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10 February 2020

author name string

Sukru Sadik Oner

1

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10 February 2020

Ningfei An

2

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10 February 2020

Ali Vural

3

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10 February 2020

Billy Breton

4

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10 February 2020

language of work or name

English

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publication date

17 August 2010

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10 February 2020

number of pages

10

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Journal of Biological Chemistry

inferred from page(s)

published in

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10 February 2020

volume

285

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10 February 2020

issue

44

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10 February 2020

page(s)

33949-33958

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Activator of G protein signaling 3 promotes epithelial cell proliferation in PKD.

10 February 2020

cites work

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LGN regulates mitotic spindle orientation during epithelial morphogenesis

6 July 2018

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A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation.

6 July 2018

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6 July 2018

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6 July 2018

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Up-regulation of AGS3 during morphine withdrawal promotes cAMP superactivation via adenylyl cyclase 5 and 7 in rat nucleus accumbens/striatal neurons

6 July 2018

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GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling

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A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics

6 July 2018

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Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma

6 July 2018

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The PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins

6 July 2018

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Ric-8A catalyzes guanine nucleotide exchange on G alphai1 bound to the GPR/GoLoco exchange inhibitor AGS3.

6 July 2018

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Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function

6 July 2018

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Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins.

6 July 2018

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Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factor

6 July 2018

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A specific role of AGS3 in the surface expression of plasma membrane proteins

6 July 2018

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Functional selectivity through protean and biased agonism: who steers the ship?

6 July 2018

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Galphai generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts

6 July 2018

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G protein beta gamma subunit interaction with the dynein light-chain component Tctex-1 regulates neurite outgrowth

6 July 2018

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Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling.

6 July 2018

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N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells

6 July 2018

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Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes.

6 July 2018

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The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division

6 July 2018

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Modulation of basal and receptor-induced GIRK potassium channel activity and neuronal excitability by the mammalian PINS homolog LGN.

6 July 2018

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Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats

6 July 2018

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mu opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis

6 July 2018

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Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma

6 July 2018

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6 July 2018

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Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors

6 July 2018

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Asymmetric cell divisions promote stratification and differentiation of mammalian skin

6 July 2018

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G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors

6 July 2018

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Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behavior

6 July 2018

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Real-time monitoring of receptor and G-protein interactions in living cells.

6 July 2018

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Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins

6 July 2018

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Return of the GDI: the GoLoco motif in cell division.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962495

Identification and characterization of AGS4: a protein containing three G-protein regulatory motifs that regulate the activation state of Gialpha

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2962495

Thermodynamic Characterization of the Binding of Activator of G Protein Signaling 3 (AGS3) and Peptides Derived from AGS3 with Gαi1

6 July 2018

1 reference

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Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo

6 July 2018

1 reference

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Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction

6 July 2018

1 reference

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The G-protein regulator AGS3 controls an early event during macroautophagy in human intestinal HT-29 cells.

6 July 2018

1 reference

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Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor

6 July 2018

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LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation

6 July 2018

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Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits

6 July 2018

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Expression analysis and subcellular distribution of the two G-protein regulators AGS3 and LGN indicate distinct functionality. Localization of LGN to the midbody during cytokinesis.

6 July 2018

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A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization

6 July 2018

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A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

6 July 2018

1 reference

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Galpha i3 binding to calnuc on Golgi membranes in living cells monitored by fluorescence resonance energy transfer of green fluorescent protein fusion proteins

6 July 2018

1 reference

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Protein localization during asymmetric cell division

6 July 2018

1 reference

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Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system

6 July 2018

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RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity

6 July 2018

1 reference

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Identification of a truncated form of the G-protein regulator AGS3 in heart that lacks the tetratricopeptide repeat domains.

6 July 2018

1 reference

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Activator of G protein signaling 3 is a guanine dissociation inhibitor for Galpha i subunits

6 July 2018

1 reference

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Selective interaction of AGS3 with G-proteins and the influence of AGS3 on the activation state of G-proteins

6 July 2018

1 reference

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AGS3 inhibits GDP dissociation from galpha subunits of the Gi family and rhodopsin-dependent activation of transducin

6 July 2018

1 reference

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Stabilization of the GDP-bound conformation of Gialpha by a peptide derived from the G-protein regulatory motif of AGS3.

6 July 2018

1 reference

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Receptor-independent activators of heterotrimeric G-protein signaling pathways

6 July 2018

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Genetic screens in yeast to identify mammalian nonreceptor modulators of G-protein signaling

6 July 2018

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The GoLoco motif: a Galphai/o binding motif and potential guanine-nucleotide exchange factor

6 July 2018

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Mechanism of RGS4, a GTPase-activating Protein for G Protein α Subunits

6 July 2018

1 reference

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The disaggregation theory of signal transduction revisited: further evidence that G proteins are multimeric and disaggregate to monomers when activated

6 July 2018

1 reference

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A mutant alpha subunit of Gi2 induces neoplastic transformation of Rat-1 cells

6 July 2018

1 reference

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RGS-7 completes a receptor-independent heterotrimeric G protein cycle to asymmetrically regulate mitotic spindle positioning in C. elegans

6 July 2018

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AGS3 and signal integration by Galpha(s)- and Galpha(i)-coupled receptors: AGS3 blocks the sensitization of adenylyl cyclase following prolonged stimulation of a Galpha(i)-coupled receptor by influencing processing of Galpha(i).

28 October 2018

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Influence of cytosolic AGS3 on receptor--G protein coupling

28 October 2018

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Distinct roles for Galpha and Gbetagamma in regulating spindle position and orientation in Caenorhabditis elegans embryos

28 October 2018

1 reference

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A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila

28 October 2018

1 reference

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Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization

28 October 2018

1 reference

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G protein beta gamma subunits from bovine brain and retina: equivalent catalytic support of ADP-ribosylation of alpha subunits by pertussis toxin but differential interactions with Gs alpha

28 October 2018

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12 December 2020

Selective uncoupling of RGS action by a single point mutation in the G protein alpha-subunit

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12 December 2020

A point mutation in Galphao and Galphai1 blocks interaction with regulator of G protein signaling proteins

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12 December 2020

Signaling by a non-dissociated complex of G protein βγ and α subunits stimulated by a receptor-independent activator of G protein signaling, AGS8

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.138073

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20716524 AND SRC:MED&resulttype=core&format=json

release_dj3myi3xzfh4rdx2seggy5xmmu

10 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dj3myi3xzfh4rdx2seggy5xmmu

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20716524 AND SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

20716524

1 reference