Transcriptional regulation of renal cytoprotective genes by Nrf2 and its potential use as a therapeutic target to mitigate cisplatin-induced nephrotoxicity. (Q34214639)

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English	Transcriptional regulation of renal cytoprotective genes by Nrf2 and its potential use as a therapeutic target to mitigate cisplatin-induced nephrotoxicity.	scientific article

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7 February 2020

Transcriptional regulation of renal cytoprotective genes by Nrf2 and its potential use as a therapeutic target to mitigate cisplatin-induced nephrotoxicity (English)

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7 February 2020

Lauren M Aleksunes

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7 February 2020

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Michael J Goedken

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7 February 2020

Cheryl E Rockwell

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7 February 2020

Juergen Thomale

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7 February 2020

Jose E Manautou

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7 February 2020

Curtis D Klaassen

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7 February 2020

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6 July 2010

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7 February 2020

Journal of Pharmacology and Experimental Therapeutics

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7 February 2020

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7 February 2020

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7 February 2020

2-12

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7 February 2020

Activation of Nrf2 by cadmium and its role in protection against cadmium-induced apoptosis in rat kidney cells

1 reference

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5 July 2018

Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity

1 reference

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5 July 2018

Application of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers

1 reference

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5 July 2018

Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957774

5 July 2018

Renal xenobiotic transporters are differentially expressed in mice following cisplatin treatment

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5 July 2018

Coordinated induction of Nrf2 target genes protects against iron nitrilotriacetate (FeNTA)-induced nephrotoxicity.

1 reference

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5 July 2018

Ochratoxin A impairs Nrf2-dependent gene expression in porcine kidney tubulus cells

1 reference

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5 July 2018

Transcriptomic analysis of nephrotoxicity induced by cephaloridine, a representative cephalosporin antibiotic

1 reference

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5 July 2018

Cisplatin nephrotoxicity: mechanisms and renoprotective strategies

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5 July 2018

Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway

1 reference

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5 July 2018

Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease

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5 July 2018

Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.

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5 July 2018

The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta

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5 July 2018

Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury

1 reference

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5 July 2018

Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide

1 reference

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5 July 2018

Multidrug resistance associated protein 2 mediates transport of prostaglandin E2

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5 July 2018

Role of Nrf2 in the regulation of the Mrp2 (ABCC2) gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957774

5 July 2018

The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling

1 reference

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5 July 2018

Genetic dissection of systemic autoimmune disease in Nrf2-deficient mice

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5 July 2018

Identification of platform-independent gene expression markers of cisplatin nephrotoxicity

1 reference

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5 July 2018

Overexpression of cMOAT (MRP2/ABCC2) is associated with decreased formation of platinum-DNA adducts and decreased G2-arrest in melanoma cells resistant to cisplatin

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The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

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5 July 2018

Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957774

5 July 2018

Transcription factor-kappa B (NF-kappa B) and renal disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957774

5 July 2018

Detection of chemical-induced differential expression of rat hepatic cytochrome P450 mRNA transcripts using branched DNA signal amplification technology

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5 July 2018

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

1 reference

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5 July 2018

Transport of glutathione conjugates and glucuronides by the multidrug resistance proteins MRP1 and MRP2

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5 July 2018

Cross-resistance to diverse drugs is associated with primary cisplatin resistance in ovarian cancer cell lines.

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5 July 2018

Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element

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5 July 2018

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5 July 2018

CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes

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28 October 2018

Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice.

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28 October 2018

A possible role of nrf2 in prevention of renal oxidative damage by ferric nitrilotriacetate

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28 October 2018

Adduct-specific monoclonal antibodies for the measurement of cisplatin-induced DNA lesions in individual cell nuclei

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28 October 2018

Effect of concurrent medications on cisplatin-induced nephrotoxicity in patients with head and neck cancer

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28 October 2018

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28 October 2018

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28 October 2018

Nrf2-deficient female mice develop lupus-like autoimmune nephritis

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12 December 2020

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12 December 2020

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7 February 2020

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