Synthetic lethal screen identifies NF-κB as a target for combination therapy with topotecan for patients with neuroblastoma (Q34205125)

31 July 2017

title

Synthetic lethal screen identifies NF-κB as a target for combination therapy with topotecan for patients with neuroblastoma (English)

1 reference

31 July 2017

0 references

1 reference

Patricia S Tsang

1

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31 July 2017

Adam T Cheuk

2

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31 July 2017

Qing-Rong Chen

3

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31 July 2017

Young K Song

4

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31 July 2017

Thomas C Badgett

5

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31 July 2017

Jun S Wei

6

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31 July 2017

Javed Khan

7

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31 July 2017

language of work or name

English

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publication date

21 March 2012

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31 July 2017

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31 July 2017

volume

12

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31 July 2017

page(s)

101

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Pilot induction regimen incorporating pharmacokinetically guided topotecan for treatment of newly diagnosed high-risk neuroblastoma: a Children's Oncology Group study

31 July 2017

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Phase II randomized comparison of topotecan plus cyclophosphamide versus topotecan alone in children with recurrent or refractory neuroblastoma: a Children's Oncology Group study

5 July 2018

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Screening a panel of drugs with diverse mechanisms of action yields potential therapeutic agents against neuroblastoma

5 July 2018

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NF-kappaB inhibition through proteasome inhibition or IKKbeta blockade increases the susceptibility of melanoma cells to cytostatic treatment through distinct pathways

5 July 2018

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New targets of PS-341: BAFF and APRIL.

5 July 2018

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A selective small-molecule nuclear factor-kappaB inhibitor from a high-throughput cell-based assay for "activator protein-1 hits".

5 July 2018

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Phase I study of ch14.18 with granulocyte-macrophage colony-stimulating factor and interleukin-2 in children with neuroblastoma after autologous bone marrow transplantation or stem-cell rescue: a report from the Children's Oncology Group

5 July 2018

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Bortezomib inhibits nuclear factor-kappaB dependent survival and has potent in vivo activity in mesothelioma.

5 July 2018

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5 July 2018

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Nuclear factor-kappaB in cancer development and progression

5 July 2018

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5 July 2018

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Hematologic safety and tolerability of topotecan in recurrent ovarian cancer and small cell lung cancer: an integrated analysis

5 July 2018

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

5 July 2018

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5 July 2018

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Missing pieces in the NF-kappaB puzzle

5 July 2018

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5 July 2018

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5 July 2018

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Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group

5 July 2018

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A phase I/IB trial of murine monoclonal anti-GD2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma: a report of the Children's Cancer Group

5 July 2018

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

5 July 2018

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5 July 2018

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5 July 2018

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Pilot study of topotecan and high-dose cyclophosphamide for resistant pediatric solid tumors.

21 January 2018

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Topotecan in pediatric patients with recurrent and progressive solid tumors: a Pediatric Oncology Group phase II study

21 January 2018

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21 January 2018

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Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition.

28 October 2018

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MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo

28 October 2018

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12 December 2020

On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

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12 December 2020

Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin

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12 December 2020

Surgical risk factors in primary surgery for localized neuroblastoma: the LNESG1 study of the European International Society of Pediatric Oncology Neuroblastoma Group

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Cyclophosphamide plus topotecan in children with recurrent or refractory solid tumors: a Pediatric Oncology Group phase II study

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12 December 2020

Identifiers

DOI

10.1186/1471-2407-12-101

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference

31 July 2017

1 reference