Molecular targets for pharmacological cytoprotection (Q34198919)

31 July 2017

title

Molecular targets for pharmacological cytoprotection (English)

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31 July 2017

Balla A

1

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31 July 2017

Tóth B

2

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31 July 2017

Timár G

3

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31 July 2017

Bak J

4

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31 July 2017

Krajcsi P

5

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31 July 2017

language of work or name

English

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publication date

1 April 2001

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31 July 2017

published in

Biochemical Pharmacology

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31 July 2017

volume

61

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31 July 2017

issue

7

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31 July 2017

page(s)

769-777

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Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

31 July 2017

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Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

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A model for p53-induced apoptosis

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Mitochondrial control of apoptosis

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Emerging roles of caspase-3 in apoptosis

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Redox Regulation of Programmed Cell Death in Lymphocytes

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Metabolic activation and hepatotoxicity. Effect of cysteine, N-acetylcysteine, and methionine on glutathione biosynthesis and bromobenzene toxicity in isolated rat hepatocytes

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Transport of glutathione diethyl ester into human cells

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Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anti-cytotoxic and anti-mutagenic mechanisms of action

7 January 2021

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Thiol WR-1065 and disulphide WR-33278, two metabolites of the drug ethyol (WR-2721), protect DNA against fast neutron-induced strand breakage

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A risk-benefit assessment of amifostine in cytoprotection

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Brain iron delocalization and lipid peroxidation following cardiac arrest

7 January 2021

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Early treatment with deferoxamine limits myocardial ischemic/reperfusion injury

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Intramuscular desferrioxamine in patients with Alzheimer's disease

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Pharmacodynamics of the hydrolysis-activation of the cardioprotective agent ( )-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane

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The hydrolysis product of ICRF-187 promotes iron-catalysed hydroxyl radical production via the Fenton reaction

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Salen-manganese complexes are superoxide dismutase-mimics

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A novel biologically active seleno-organic compound—1

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The reaction of ebselen with peroxynitrite

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Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

7 January 2021

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Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

7 January 2021

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Etoposide-induced activation of c-jun N-terminal kinase (JNK) correlates with drug-induced apoptosis in salivary gland acinar cells

7 January 2021

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The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons.

7 January 2021

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Interaction among mitochondria, mitogen-activated protein kinases, and nuclear factor-kappaB in cellular models of Parkinson's disease

7 January 2021

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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Stress-activated protein kinases: activation, regulation and function.

7 January 2021

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Activation of the c-Jun N-terminal kinase/stress-activated protein kinase pathway by overexpression of caspase-8 and its homologs

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Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

7 January 2021

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p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors

7 January 2021

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Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

7 January 2021

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Motoneuron Apoptosis Is Blocked by CEP-1347 (KT 7515), a Novel Inhibitor of the JNK Signaling Pathway

7 January 2021

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Chronic sparing of delayed alternation performance and choline acetyltransferase activity by CEP-1347/KT-7515 in rats with lesions of nucleus basalis magnocellularis

7 January 2021

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Role of poly(ADP-ribose) formation in DNA repair

7 January 2021

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Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

7 January 2021

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Apoptosis in the absence of poly-(ADP-ribose) polymerase

7 January 2021

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Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

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7 January 2021

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Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

7 January 2021

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A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets

7 January 2021

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7 January 2021

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7 January 2021

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Inhibitors and activators of ADP-ribosylation reactions

7 January 2021

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Lessons learned from nitric oxide synthase knockout animals

7 January 2021

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Required and nonessential functions of nuclear factor-kappa B in bone cells

7 January 2021

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Chronic Inflammation and Susceptibility to Bacterial Infections in Mice Lacking the Polypeptide (p)105 Precursor (NF-κB1) but Expressing p50

7 January 2021

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BGP-15, a nicotinic amidoxime derivate protecting heart from ischemia reperfusion injury through modulation of poly(ADP-ribose) polymerase

7 January 2021

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Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase

7 January 2021

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p53 mutations in human cancers

7 January 2021

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Pharmacological rescue of mutant p53 conformation and function

7 January 2021

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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

7 January 2021

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Deciphering the pathways of life and death

7 January 2021

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Caspase knockouts: matters of life and death.

7 January 2021

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Inhibition of human caspases by peptide-based and macromolecular inhibitors

7 January 2021

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Attenuation of Ischemia/Reperfusion Injury in Rats by a Caspase Inhibitor

7 January 2021

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Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

7 January 2021

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Neuroprotection by a caspase inhibitor in acute bacterial meningitis

7 January 2021

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Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

7 January 2021

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Neuroprotective therapies.

7 January 2021

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Parkinson disease: a new link between monoamine oxidase and mitochondrial electron flow

7 January 2021

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Inhibition of anoxia-induced injury in heart myocytes by cyclosporin A

7 January 2021

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Protection by cyclosporin A of cultured hepatocytes from the toxic consequences of the loss of mitochondrial energization produced by 1-methyl-4-phenylpyridinium

7 January 2021

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Suppression or induction of apoptosis by opposing pathways downstream from calcium-activated calcineurin

7 January 2021

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Cyclosporin A significantly ameliorates cortical damage following experimental traumatic brain injury in rodents

7 January 2021

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

7 January 2021

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NF-kappaB functions as both a proapoptotic and antiapoptotic regulatory factor within a single cell type

7 January 2021

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Janus faces of nitric oxide

7 January 2021

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Diverse functions of JNK signaling and c-Jun in stress response and apoptosis

7 January 2021

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Bimoclomol: A nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects

7 January 2021

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Pharmacokinetics and mechanism of action of detoxifying low-molecular-weight thiols

7 January 2021

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Localized Areas of High Alkaline Phosphatase Activity in Endothelium of Arteries

7 January 2021

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Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene

7 January 2021

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Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus

7 January 2021

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Selective inhibition of mutant human mitochondrial DNA replication in vitro by peptide nucleic acids

7 January 2021

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Calcium, free radicals, and excitotoxic neuronal death in primary cell culture

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(00)00585-2

1 reference

31 July 2017

1 reference