Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents (Q34188494)

31 July 2017

title

Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents (English)

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31 July 2017

Zhan Xiao

1

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31 July 2017

Zehan Chen

2

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31 July 2017

Angelo H Gunasekera

3

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31 July 2017

Thomas J Sowin

4

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31 July 2017

Saul H Rosenberg

5

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31 July 2017

Steve Fesik

6

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31 July 2017

Haiying Zhang

7

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31 July 2017

language of work or name

English

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publication date

3 April 2003

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Journal of Biological Chemistry

31 July 2017

published in

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31 July 2017

volume

278

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31 July 2017

issue

24

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31 July 2017

page(s)

21767-21773

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Rapid destruction of human Cdc25A in response to DNA damage

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

21 January 2018

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Cell-cycle checkpoint kinases: checking in on the cell cycle

21 January 2018

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The DNA damage response: putting checkpoints in perspective

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M300229200

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M300229200

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

S phase and G2 arrests induced by topoisomerase I poisons are dependent on ATR kinase function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

CDC25 phosphatases as potential human oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

DNA and its associated processes as targets for cancer therapy

21 January 2018

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Dual G1 and G2 phase inhibition by a novel, selective Cdc25 inhibitor 6-chloro-7-[corrected](2-morpholin-4-ylethylamino)-quinoline-5,8-dione

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34(cdc2)/cyclin B activation in hamster BHK21 cells arrested with hydroxyurea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

Phosphorylation of human CDC25B phosphatase by CDK1-cyclin A triggers its proteasome-dependent degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M300229200

Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M300229200

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31 July 2017

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