A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis. (Q34178953)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

28 January 2020

title

A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

28 January 2020

Kai Johnsson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Hirohito Haruki

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

28 January 2020

Miriam Grønlund Pedersen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

28 January 2020

Evelyne Muller

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

28 January 2020

publication date

17 April 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

28 January 2020

published in

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

28 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

28 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

375-383

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

Target deconvolution strategies in drug discovery

28 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Recent advances and method development for drug target identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Target profiling of small molecules by chemical proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

A three-hybrid system for detecting small ligand-protein receptor interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

A general method for the covalent labeling of fusion proteins with small molecules in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

In vivo characterization of the drug resistance profile of the major ABC transporters and other components of the yeast pleiotropic drug resistance network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Septin stability and recycling during dynamic structural transitions in cell division and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Induced protein dimerization in vivo through covalent labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Importance of a hydrophobic residue in binding and catalysis by dihydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Hydrophobic interactions via mutants of Escherichia coli dihydrofolate reductase: separation of binding and catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Improving yeast two-hybrid screening systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Increasing specificity in high-throughput yeast two-hybrid experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

A quantitative analysis of kinase inhibitor selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Emerging roles of the oxysterol-binding protein family in metabolism, transport, and signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Structural mechanism for statin inhibition of HMG-CoA reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Internalization and recycling of the human prostacyclin receptor is modulated through its isoprenylation-dependent interaction with the delta subunit of cGMP phosphodiesterase 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Mechanisms of statin-mediated inhibition of small G-protein function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

The long journey of salicylates in ulcerative colitis: The past and the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Tetrahydrobiopterin biosynthesis, regeneration and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

MRP2 mediated drug-drug interaction: indomethacin increases sulfasalazine absorption in the small intestine, potentially decreasing its colonic targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Colonic targeting of aminosalicylates for the treatment of ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Kinetic basis for selective inhibition of cyclo-oxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

A GTP cyclohydrolase 1 genetic variant delays cancer pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Sulfasalazine blocks the development of tactile allodynia in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Tetrahydrobiopterin deficiencies without hyperphenylalaninemia: diagnosis and genetics of dopa-responsive dystonia and sepiapterin reductase deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.557

Suppression of acute experimental colitis by a highly selective inducible nitric-oxide synthase inhibitor, N-[3-(aminomethyl)benzyl]acetamidine

21 January 2018

1 reference

12 December 2020

Oral 5-aminosalicylic acid for maintenance of remission in ulcerative colitis

1 reference

12 December 2020

Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase

1 reference

12 December 2020

Inhibition of folate-dependent enzymes by non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

Crystal Structure of Anti-Configuration of Indomethacin and Leukotriene B4 12-Hydroxydehydrogenase/15-Oxo-Prostaglandin 13-Reductase Complex Reveals the Structural Basis of Broad Spectrum Indomethacin Efficacy

1 reference

12 December 2020

New inhibitors of sepiapterin reductase. Lack of an effect of intracellular tetrahydrobiopterin depletion upon in vitro proliferation of two human cell lines

1 reference

12 December 2020

Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle

1 reference

12 December 2020

Colonic azodisalicylate metabolism determined by in vivo dialysis in healthy volunteers and patients with ulcerative colitis

1 reference

12 December 2020

Which component of sulphasalazine is active in rheumatoid arthritis?

1 reference

12 December 2020

Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease

1 reference

12 December 2020

A three-hybrid approach to scanning the proteome for targets of small molecule kinase inhibitors

1 reference

12 December 2020

Inhibition of tetrahydrobiopterin synthesis reduces in vivo nitric oxide production in experimental endotoxic shock

1 reference

12 December 2020

Plasma and synovial fluid concentrations of sulphasalazine and two of its metabolites in rheumatoid arthritis

1 reference

12 December 2020

Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.557

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499265 AND SRC:MED&resulttype=core&format=json

release_5k7flpsfonfzpjltvilnxm34am

28 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5k7flpsfonfzpjltvilnxm34am

24 November 2022

mapped directly with Wikidata item

1 reference