Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16. (Q34178201)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686044 AND SRC:MED&resulttype=core&format=json

9 February 2020

title

Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16 (English)

1 reference

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9 February 2020

1 reference

0 references

1

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9 February 2020

2

Dennis R Burton

1 reference

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9 February 2020

language of work or name

English

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publication date

4 August 2010

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9 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686044 AND SRC:MED&resulttype=core&format=json

9 February 2020

volume

84

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9 February 2020

issue

20

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9 February 2020

page(s)

10510-10521

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686044 AND SRC:MED&resulttype=core&format=json

A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals

9 February 2020

cites work

1 reference

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

28 July 2018

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Glycosylation site-specific analysis of clade C HIV-1 envelope proteins

28 July 2018

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Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays

28 July 2018

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Glycosylation site-specific analysis of HIV envelope proteins (JR-FL and CON-S) reveals major differences in glycosylation site occupancy, glycoform profiles, and antigenic epitopes' accessibility

28 July 2018

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28 July 2018

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Removal of a single N-linked glycan in human immunodeficiency virus type 1 gp120 results in an enhanced ability to induce neutralizing antibody responses

28 July 2018

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Aiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidates

28 July 2018

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28 July 2018

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Structures of complement component C3 provide insights into the function and evolution of immunity

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Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

28 July 2018

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Stoichiometry of antibody neutralization of human immunodeficiency virus type 1.

28 July 2018

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Characterization of glycopeptides from HIV-I(SF2) gp120 by liquid chromatography mass spectrometry

28 July 2018

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Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV, and HCV envelopes and influenza hemagglutinin

28 July 2018

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N-linked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies

28 July 2018

1 reference

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Removal of N-linked glycosylation sites in the V1 region of simian immunodeficiency virus gp120 results in redirection of B-cell responses to V3.

28 July 2018

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Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

28 July 2018

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The role of glucosidase II and endomannosidase in glucose trimming of asparagine-linked oligosaccharides

28 July 2018

1 reference

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Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.

28 July 2018

1 reference

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Structure and function in rhodopsin: high-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line

28 July 2018

1 reference

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Antibodies, viruses and vaccines

28 July 2018

1 reference

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The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

28 July 2018

1 reference

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Role of N-linked glycans in a human immunodeficiency virus envelope glycoprotein: effects on protein function and the neutralizing antibody response

28 July 2018

1 reference

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Neutralization synergy of human immunodeficiency virus type 1 primary isolates by cocktails of broadly neutralizing antibodies.

28 July 2018

1 reference

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N-linked glycosylation sites adjacent to and within the V1/V2 and the V3 loops of dualtropic human immunodeficiency virus type 1 isolate DH12 gp120 affect coreceptor usage and cellular tropism

28 July 2018

1 reference

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Mass spectrometric characterization of the glycosylation pattern of HIV-gp120 expressed in CHO cells

28 July 2018

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V2 loop glycosylation of the human immunodeficiency virus type 1 SF162 envelope facilitates interaction of this protein with CD4 and CCR5 receptors and protects the virus from neutralization by anti-V3 loop and anti-CD4 binding site antibodies

28 July 2018

1 reference

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DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

28 July 2018

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Stoichiometry of monoclonal antibody neutralization of T-cell line-adapted human immunodeficiency virus type 1

28 July 2018

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The antigenic structure of the HIV gp120 envelope glycoprotein

28 July 2018

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A role for carbohydrates in immune evasion in AIDS.

28 July 2018

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Glycosylation: heterogeneity and the 3D structure of proteins

28 July 2018

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N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with impaired gp120 shedding and gp41 exposure

28 July 2018

1 reference

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N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with changes in antibody recognition of the V1/V2 region of gp120

28 July 2018

1 reference

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Glycosylation is necessary for the correct folding of human immunodeficiency virus gp120 in CD4 binding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950566

The alpha-glucosidase inhibitor N-butyldeoxynojirimycin inhibits human immunodeficiency virus entry at the level of post-CD4 binding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950566

Swainsonine: an inhibitor of glycoprotein processing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950566

Assembly of asparagine-linked oligosaccharides

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950566

Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1

28 July 2018

1 reference

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Aminosugar derivatives as potential anti-human immunodeficiency virus agents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950566

Inhibition of HIV replication by amino-sugar derivatives

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950566

Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950566

Carbohydrates of human immunodeficiency virus. Structures of oligosaccharides linked to the envelope glycoprotein 120.

28 July 2018

1 reference

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Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine

28 July 2018

1 reference

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Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells

28 July 2018

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Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants

28 July 2018

1 reference

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Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I.

28 July 2018

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Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.

28 July 2018

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Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody

28 October 2018

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An HIV vaccine--evolving concepts

28 October 2018

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Progress and obstacles in the development of an AIDS vaccine

28 October 2018

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Monoglucosylated glycans in the secreted human complement component C3: implications for protein biosynthesis and structure

28 October 2018

1 reference

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HIV vaccine design and the neutralizing antibody problem

28 October 2018

1 reference

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Biases and complex patterns in the residues flanking protein N-glycosylation sites

28 October 2018

1 reference

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Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition.

28 October 2018

1 reference

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Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic reticulum

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950566

Effects of the imino sugar N-butyldeoxynojirimycin on the N-glycosylation of recombinant gp120.

28 October 2018

1 reference

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28 October 2018

gp41: HIV's shy protein

1 reference

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Immunology and the elusive AIDS vaccine

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20686044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/20686044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.00552-10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686044 AND SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686044 AND SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

20686044

1 reference