The synthetic triterpenoid, CDDO-Me, modulates the proinflammatory response to in vivo lipopolysaccharide challenge (Q34175650)

31 July 2017

title

The synthetic triterpenoid, CDDO-Me, modulates the proinflammatory response to in vivo lipopolysaccharide challenge (English)

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31 July 2017

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Jeffery J Auletta

1

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31 July 2017

Jennifer L Alabran

2

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31 July 2017

Byung-Gyu Kim

3

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31 July 2017

Colin J Meyer

4

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31 July 2017

John J Letterio

5

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31 July 2017

publication date

1 July 2010

1 reference

Journal of Interferon and Cytokine Research

31 July 2017

published in

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31 July 2017

volume

30

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31 July 2017

issue

7

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31 July 2017

page(s)

497-508

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The triterpenoid CDDO limits inflammation in preclinical models of cystic fibrosis lung disease

31 July 2017

cites work

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5 July 2018

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The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta

5 July 2018

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5 July 2018

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Triterpenoid CDDO-Me blocks the NF-kappaB pathway by direct inhibition of IKKbeta on Cys-179.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells

5 July 2018

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5 July 2018

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5 July 2018

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The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients

5 July 2018

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Deactivation of the innate cellular immune response following endotoxic and surgical injury.

5 July 2018

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Toll-like receptors: critical proteins linking innate and acquired immunity

5 July 2018

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Heme oxygenase: colors of defense against cellular stress

5 July 2018

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Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

5 July 2018

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A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity.

5 July 2018

1 reference

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Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages

5 July 2018

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5 July 2018

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Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B.

28 October 2018

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Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling

28 October 2018

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A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways

28 October 2018

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Endotoxin-induced mortality is related to increased oxidative stress and end-organ dysfunction, not refractory hypotension, in heme oxygenase-1-deficient mice

28 October 2018

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Synthetic oleanane and ursane triterpenoids with modified rings A and C: a series of highly active inhibitors of nitric oxide production in mouse macrophages

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950060

Distinct patterns and kinetics of chemokine production regulate dendritic cell function.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950060

Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950060

Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expression

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950060

Endotoxin fails to induce IFN-gamma in endotoxin-tolerant mice: deficiencies in both IL-12 heterodimer production and IL-12 responsiveness

28 October 2018

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12 December 2020

SOCS-1 participates in negative regulation of LPS responses

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12 December 2020

IL-12 Suppression During Experimental Endotoxin Tolerance: Dendritic Cell Loss and Macrophage Hyporesponsiveness

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12 December 2020

Heme oxygenase-1-mediated CD4 CD25high regulatory T cells suppress allergic airway inflammation

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12 December 2020

Endotoxin tolerance from lipopolysaccharide pretreatment induces nuclear factor-kappaB alterations not present in C3H/HeJ mice

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12 December 2020

Distinct phases in recovery of reconstituted innate cellular-mediated immunity after murine syngeneic bone marrow transplantation

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12 December 2020

Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression

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12 December 2020

Design and synthesis of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, a novel and highly active inhibitor of nitric oxide production in mouse macrophages

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12 December 2020

Endotoxin tolerance: A review

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12 December 2020

In vivo and in vitro regulation of type I IFN synthesis by synergistic effects of CD40 and type II IFN

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12 December 2020

Identifiers

DOI

10.1089/JIR.2009.0100

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31 July 2017

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31 July 2017

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