Intestinal IgA synthesis: regulation of front-line body defences (Q34168492)

31 July 2017

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title

Intestinal IgA synthesis: regulation of front-line body defences (English)

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31 July 2017

2

Tasuku Honjo

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Sidonia Făgărășan

series ordinal

1

object named as

Sidonia Fagarasan

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31 July 2017

publication date

1 January 2003

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Nature Reviews Immunology

31 July 2017

published in

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31 July 2017

volume

3

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31 July 2017

issue

1

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31 July 2017

page(s)

63-72

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What brought the adaptive immune system to vertebrates?--The jaw hypothesis and the seahorse

31 July 2017

cites work

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Regional specialization in the mucosal immune system: what happens in the microcompartments?

31 March 2020

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IgA and the IgA Fc receptor.

31 March 2020

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Transepithelial transport of immunoglobulins

31 March 2020

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Comparative immunological studies of the immune globulins of human milk and of blood serum

31 March 2020

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CHARACTERISTICS OF AN IMMUNE SYSTEM COMMON TO CERTAIN EXTERNAL SECRETIONS

31 March 2020

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Lymphocyte-filled villi: comparison with other lymphoid aggregations in the mucosa of the human small intestine.

31 March 2020

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Identification of multiple isolated lymphoid follicles on the antimesenteric wall of the mouse small intestine

31 March 2020

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Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora

31 March 2020

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Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit

31 March 2020

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Influences of microbiota on intestinal immune system development

31 March 2020

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Relationship between expression of IgA by Peyer's patch cells and functional IgA memory cells

31 March 2020

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T cell and cytokine regulation of the IgA response

31 March 2020

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IgVH gene analysis suggests that peritoneal B cells do not contribute to the gut immune system in man

31 March 2020

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Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavity

31 March 2020

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A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria

31 March 2020

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The gut-associated lymphoid system: nature and properties of the large dividing cells

31 March 2020

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Mesenteric lymph node B lymphoblasts which home to the small intestine are precommitted to IgA synthesis

31 March 2020

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Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

31 March 2020

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Identification of a murine Peyer's patch--specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha

31 March 2020

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MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1

31 March 2020

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Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.

31 March 2020

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Critical role for β7 integrins in formation of the gut-associated lymphoid tissue

31 March 2020

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Chemokines and cell migration in secondary lymphoid organs

31 March 2020

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Chemokine requirements for B cell entry to lymph nodes and Peyer's patches.

31 March 2020

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The intestinal chemokine thymus-expressed chemokine (CCL25) attracts IgA antibody-secreting cells

31 March 2020

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Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity

31 March 2020

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The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system

31 March 2020

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Signaling via LTbetaR on the lamina propria stromal cells of the gut is required for IgA production

31 March 2020

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Postgestational lymphotoxin/lymphotoxin beta receptor interactions are essential for the presence of intestinal B lymphocytes.

31 March 2020

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Cytokine regulation of secondary lymphoid organ development.

31 March 2020

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Alymphoplasia (aly)-type nuclear factor kappaB-inducing kinase (NIK) causes defects in secondary lymphoid tissue chemokine receptor signaling and homing of peritoneal cells to the gut-associated lymphatic tissue system

31 March 2020

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A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice

31 March 2020

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Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase

31 March 2020

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Analysis of Expression of Lymphocyte Homing-Related Adhesion Molecules in ALY Mice Deficient in Lymph Nodes and Peyer's Patches

31 March 2020

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CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity

31 March 2020

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Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor

31 March 2020

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Impaired mucosal immune responses in interleukin 4-targeted mice

31 March 2020

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Lymph node genesis is induced by signaling through the lymphotoxin beta receptor

31 March 2020

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Alternate mucosal immune system: organized Peyer's patches are not required for IgA responses in the gastrointestinal tract

31 March 2020

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

31 March 2020

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Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

31 March 2020

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Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

31 March 2020

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In situ class switching and differentiation to IgA-producing cells in the gut lamina propria

31 March 2020

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Increased frequency of surface IgA-positive plasma cells in the intestinal lamina propria and decreased IgA excretion in hyper IgA (HIGA) mice, a murine model of IgA nephropathy with hyperserum IgA

31 March 2020

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A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs

31 March 2020

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High frequency class switching of an IgM B lymphoma clone CH12F3 to IgA cells.

31 March 2020

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Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

31 March 2020

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Circular DNA is excised by immunoglobulin class switch recombination

31 March 2020

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Circular DNA is a product of the immunoglobulin class switch rearrangement

31 March 2020

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Switch circular DNA formed in cytokine-treated mouse splenocytes: evidence for intramolecular DNA deletion in immunoglobulin class switching

31 March 2020

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Epithelial M cells: differentiation and function

31 March 2020

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Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

31 March 2020

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Junctional complexes in various epithelia

31 March 2020

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Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells

31 March 2020

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Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes

31 March 2020

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Transforming growth factor beta induces IgA production and acts additively with interleukin 5 for IgA production

31 March 2020

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TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo

31 March 2020

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The role of interleukin-6 in mucosal IgA antibody responses in vivo

31 March 2020

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Human dendritic cells skew isotype switching of CD40-activated naive B cells towards IgA1 and IgA2.

31 March 2020

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DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

31 March 2020

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T-Independent immune response: new aspects of B cell biology

31 March 2020

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Defect in IgV gene somatic hypermutation in common variable immuno-deficiency syndrome

31 March 2020

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Common variable immunodeficiency syndrome and nodular lymphoid hyperplasia in the small intestine.

31 March 2020

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Absence of epithelial immunoglobulin A transport, with increased mucosal leakiness, in polymeric immunoglobulin receptor/secretory component-deficient mice

31 March 2020

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Maturation of the immune response in germinal centers

31 March 2020

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Analysis of somatic hypermutation in mouse Peyer's patches using immunoglobulin kappa light-chain transgenes

31 March 2020

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Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation

31 March 2020

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Linking class-switch recombination with somatic hypermutation

31 March 2020

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Molecular mechanism of class switch recombination: linkage with somatic hypermutation

31 March 2020

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Structure of the intestinal flora responsible for development of the gut immune system in a rodent model

31 March 2020

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Human IgA- and IgM-secreting intestinal plasma cells carry heavily mutated VH region genes

31 March 2020

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Characteristics of IgVH genes used by human intestinal plasma cells from childhood

31 March 2020

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Sequence analysis of light chain genes from human intestinal plasma cells demonstrates that lambda genes are almost all in-frame and highly mutated and most kappa genes are highly mutatedwhen in-frame and minimally mutated when out-of-frame

31 March 2020

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IgA production without mu or delta chain expression in developing B cells

31 March 2020

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A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

31 March 2020

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In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

31 March 2020

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Commensal host-bacterial relationships in the gut

31 March 2020

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Molecular analysis of commensal host-microbial relationships in the intestine

31 March 2020

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The AID enzyme induces class switch recombination in fibroblasts

31 March 2020

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Demonstration of M cells in the specialized follicle-associated epithelium overlying isolated lymphoid follicles in the gut.

31 March 2020

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI982

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31 July 2017

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