Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol. (Q34163303)

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1 February 2020

title

Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol (English)

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main subject

Listeria monocytogenes

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1

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Daniel A Portnoy

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1 February 2020

author name string

Chelsea E Witte

2

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1 February 2020

Jason Zemansky

3

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Bill Hanson

4

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Peter Lauer

5

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publication date

22 April 2010

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1 February 2020

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1 February 2020

volume

7

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issue

5

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page(s)

412-419

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Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3.

1 February 2020

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An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

5 July 2018

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AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

5 July 2018

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

5 July 2018

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5 July 2018

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Intracellular bacteriolysis triggers a massive apoptotic cell death in Shigella-infected epithelial cells.

5 July 2018

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Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection

5 July 2018

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5 July 2018

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5 July 2018

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Listeriolysin O secreted by Listeria monocytogenes into the host cell cytosol is degraded by the N-end rule pathway

5 July 2018

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Type I interferon signaling is required for activation of the inflammasome during Francisella infection

5 July 2018

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Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation

5 July 2018

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The MogR transcriptional repressor regulates nonhierarchal expression of flagellar motility genes and virulence in Listeria monocytogenes

5 July 2018

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Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

5 July 2018

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Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity

5 July 2018

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Cryopyrin activates the inflammasome in response to toxins and ATP

5 July 2018

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Listeria monocytogenes regulates flagellar motility gene expression through MogR, a transcriptional repressor required for virulence

5 July 2018

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An update on the medical management of listeriosis

5 July 2018

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Listeria monocytogenes mutants that fail to compartmentalize listerolysin O activity are cytotoxic, avirulent, and unable to evade host extracellular defenses

5 July 2018

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5 July 2018

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Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors

5 July 2018

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The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells

5 July 2018

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5 July 2018

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The mechanism of cell death in Listeria monocytogenes-infected murine macrophages is distinct from apoptosis

5 July 2018

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5 July 2018

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Characterization of Listeria monocytogenes pathogenesis in a strain expressing perfringolysin O in place of listeriolysin O

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes

28 October 2018

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28 October 2018

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28 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20417169

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CHOM.2010.04.004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20417169 AND SRC:MED&resulttype=core&format=json

1 February 2020

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1 February 2020

PubMed publication ID

20417169

1 reference