Folylpolyglutamate synthetase gene transcription is regulated by a multiprotein complex that binds the TEL-AML1 fusion in acute lymphoblastic leukemia (Q34161064)

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English	Folylpolyglutamate synthetase gene transcription is regulated by a multiprotein complex that binds the TEL-AML1 fusion in acute lymphoblastic leukemia	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Folylpolyglutamate synthetase gene transcription is regulated by a multiprotein complex that binds the TEL-AML1 fusion in acute lymphoblastic leukemia (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

based on heuristic

inferred from title

lymphoblastic leukemia

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based on heuristic

inferred from title

Stephen P Hunger

3

object named as

Stephen Hunger

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Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Guy J Leclerc

1

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Europe PubMed Central

PubMed publication ID

31 July 2017

Christopher Sanderson

2

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Europe PubMed Central

PubMed publication ID

31 July 2017

Meenakshi Devidas

4

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Europe PubMed Central

PubMed publication ID

31 July 2017

Julio C Barredo

5

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31 July 2017

language of work or name

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publication date

9 June 2010

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Europe PubMed Central

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31 July 2017

Leukemia Research

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Europe PubMed Central

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31 July 2017

34

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Europe PubMed Central

PubMed publication ID

31 July 2017

12

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Europe PubMed Central

PubMed publication ID

31 July 2017

1601-1609

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Europe PubMed Central

PubMed publication ID

31 July 2017

Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy

1 reference

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mTOR inhibitors are synergistic with methotrexate: an effective combination to treat acute lymphoblastic leukemia.

1 reference

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Mechanisms of antifolate resistance and methotrexate efficacy in leukemia cells

1 reference

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Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy

1 reference

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5 July 2018

Molecular basis for decreased folylpoly-gamma-glutamate synthetase expression in a methotrexate resistant CCRF-CEM mutant cell line

1 reference

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Analysis of folylpoly-gamma-glutamate synthetase gene expression in human B-precursor ALL and T-lineage ALL cells

1 reference

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5 July 2018

Treatment of acute lymphoblastic leukemia

1 reference

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Pemetrexed: a multitargeted antifolate

1 reference

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Pemetrexed disodium

1 reference

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Chromatin modifying activity of leukaemia associated fusion proteins

1 reference

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Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics

1 reference

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5 July 2018

Histone deacetylase inhibition improves dendritic cell differentiation of leukemic blasts with AML1-containing fusion proteins

1 reference

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5 July 2018

Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia

1 reference

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5 July 2018

Altered gene expression of folate enzymes in adjacent mucosa is associated with outcome of colorectal cancer patients.

1 reference

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5 July 2018

Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.

1 reference

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Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues.

1 reference

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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

1 reference

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The genetics of the E2F family of transcription factors: shared functions and unique roles

1 reference

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Childhood acute lymphoblastic leukaemia--current status and future perspectives

1 reference

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5 July 2018

Sibling rivalry in the E2F family

1 reference

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5 July 2018

E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis

1 reference

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5 July 2018

Mechanisms of transcriptional repression by the t(8;21)-, t(12;21)-, and inv(16)-encoded fusion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946984

5 July 2018

Folylpoly-gamma-glutamate synthetase gene mRNA splice variants and protein expression in primary human leukemia cells, cell lines, and normal human tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946984

5 July 2018

Clinical implications of recurring chromosomal and associated molecular abnormalities in acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946984

5 July 2018

The leukemia-associated gene TEL encodes a transcription repressor which associates with SMRT and mSin3A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946984

5 July 2018

Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946984

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The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance

1 reference

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Distinct roles for Sp1 and E2F sites in the growth/cell cycle regulation of the DHFR promoter

1 reference

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Role of folylpolygutamate synthetase (FPGS) in antifolate chemotherapy; a biochemical and clinical update

1 reference

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Upstream organization of and multiple transcripts from the human folylpoly-gamma-glutamate synthetase gene

1 reference

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5 July 2018

Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: a pilot prognostic factor analysis

1 reference

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Determinants of antifolate cytotoxicity: folylpolyglutamate synthetase activity during cellular proliferation and development

1 reference

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Effect of the histone deacetylase inhibitor depsipeptide on B-cell differentiation in both TEL-AML1-positive and negative childhood acute lymphoblastic leukemia.

1 reference

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28 October 2018

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1 reference

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1 reference

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1 reference

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28 October 2018

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20538338

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based on heuristic

inferred from PubMed ID database lookup

Acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20538338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a chinese hamster cell with a temperature-sensitive mutation in folate metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20538338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemoglobin induction by Ara-C in human erythroleukemic cells (K562) is cell-cycle dependent

1 reference

https://pubmed.ncbi.nlm.nih.gov/20538338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia-associated TEL-AML1 oncoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20538338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute lymphoblastic leukemia: a Pediatric Oncology Group study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20538338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20538338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20538338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.LEUKRES.2010.05.012

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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