TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor (Q34155890)

31 July 2017

title

TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor (English)

1 reference

31 July 2017

Colleen M Dewey

1

1 reference

31 July 2017

Basar Cenik

2

1 reference

31 July 2017

Chantelle F Sephton

3

1 reference

31 July 2017

Daniel R Dries

4

1 reference

31 July 2017

Paul Mayer

5

1 reference

31 July 2017

Shannon K Good

6

1 reference

31 July 2017

Brett A Johnson

7

1 reference

31 July 2017

Joachim Herz

8

1 reference

31 July 2017

Gang Yu

9

1 reference

31 July 2017

language of work or name

English

0 references

publication date

20 December 2010

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31 July 2017

number of pages

11

1 reference

Molecular and Cellular Biology

inferred from page(s)

published in

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31 July 2017

volume

31

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31 July 2017

issue

5

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31 July 2017

page(s)

1098-1108

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describes a project that uses

31 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3067820/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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5 July 2018

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Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

5 July 2018

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5 July 2018

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5 July 2018

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TDP-43 is recruited to stress granules in conditions of oxidative insult.

5 July 2018

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5 July 2018

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5 July 2018

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Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin

5 July 2018

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5 July 2018

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Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo

5 July 2018

1 reference

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Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

5 July 2018

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5 July 2018

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Structural insights into TDP-43 in nucleic-acid binding and domain interactions

5 July 2018

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Structural determinants of the cellular localization and shuttling of TDP-43.

5 July 2018

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Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

5 July 2018

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5 July 2018

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5 July 2018

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Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival

5 July 2018

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TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing

5 July 2018

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Caspase-cleaved TAR DNA-binding protein-43 is a major pathological finding in Alzheimer's disease

5 July 2018

1 reference

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5 July 2018

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TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis

5 July 2018

1 reference

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TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

5 July 2018

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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

5 July 2018

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TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression

5 July 2018

1 reference

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5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

TDP-43 A315T mutation in familial motor neuron disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

TDP-43 proteinopathies: neurodegenerative protein misfolding diseases without amyloidosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Human pathologies associated with defective RNA transport and localization in the nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

TDP-43: a novel neurodegenerative proteinopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

A novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: role for TDP-43 in insulator function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Mammalian stress granules and processing bodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Reactive oxygen and nitrogen species are involved in sorbitol-induced apoptosis of human erithroleukaemia cells K562.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Convergence of stress granules and protein aggregates in hippocampal cornu ammonis 1 at later reperfusion following global brain ischemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

hnRNP A1 relocalization to the stress granules reflects a role in the stress response.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Delineating common molecular mechanisms in Alzheimer's and prion diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

cis-requirement for the maintenance of round spermatid-specific transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Increased sorbitol pathway activity generates oxidative stress in tissue sites for diabetic complications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Structural diversity and functional implications of the eukaryotic TDP gene family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Contribution of polyol pathway to diabetes-induced oxidative stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Multifunctional regulatory proteins that control gene expression in both the nucleus and the cytoplasm

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

hnRNP complexes: composition, structure, and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

A nuclear localization domain in the hnRNP A1 protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Mutation within TARDBP leads to frontotemporal dementia without motor neuron disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

TARDBP variation associated with frontotemporal dementia, supranuclear gaze palsy, and chorea.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

TARDBP (TDP-43) sequence analysis in patients with familial and sporadic ALS: identification of two novel mutations.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in amyotrophic lateral sclerosis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Absence of heterogeneous nuclear ribonucleoproteins and survival motor neuron protein in TDP-43 positive inclusions in frontotemporal lobar degeneration

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

TDP43 depletion rescues aberrant CFTR exon 9 skipping

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Human, Drosophila, and C.elegans TDP43: nucleic acid binding properties and splicing regulatory function

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Nuclear factor TDP-43 binds to the polymorphic TG repeats in CFTR intron 8 and causes skipping of exon 9: a functional link with disease penetrance

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Down-regulation of protein kinase C activity by sorbitol rapidly induces apoptosis in human gastric cancer cell lines

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067820

Rapid induction of apoptosis in human gastric cancer cell lines by sorbitol

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21173160

12 December 2020

inferred from PubMed ID database lookup

Contribution of TARDBP mutations to sporadic amyotrophic lateral sclerosis.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21173160

12 December 2020

inferred from PubMed ID database lookup

Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21173160

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/MCB.01279-10

1 reference

31 July 2017

1 reference

31 July 2017

1 reference