A theoretical molecular network for dyslexia: integrating available genetic findings (Q34144455)

31 July 2017

title

A theoretical molecular network for dyslexia: integrating available genetic findings (English)

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31 July 2017

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4

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31 July 2017

G Poelmans

1

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31 July 2017

J K Buitelaar

series ordinal

2

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31 July 2017

D L Pauls

series ordinal

3

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31 July 2017

language of work or name

English

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publication date

19 October 2010

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31 July 2017

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31 July 2017

volume

16

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31 July 2017

issue

4

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31 July 2017

page(s)

365-382

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Independent genome-wide scans identify a chromosome 18 quantitative-trait locus influencing dyslexia

31 July 2017

cites work

1 reference

A 77-kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United States

21 January 2018

1 reference

Genomewide scan identifies susceptibility locus for dyslexia on Xq27 in an extended Dutch family

21 January 2018

1 reference

The genetics of reading disability

21 January 2018

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Dyslexia: The evolution of a scientific concept

21 January 2018

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Genetics of developmental dyslexia

21 January 2018

1 reference

Paying attention to reading: the neurobiology of reading and dyslexia

21 January 2018

1 reference

From genes to behavior in developmental dyslexia

21 January 2018

1 reference

Coordination of actin filament and microtubule dynamics during neurite outgrowth

21 January 2018

1 reference

Progress towards a cellular neurobiology of reading disability

21 January 2018

1 reference

Suggestive linkage of developmental dyslexia to chromosome 1p34-p36.

21 January 2018

1 reference

Association of reading disability on chromosome 6p22 in the Afrikaner population

21 January 2018

1 reference

Supportive evidence for the DYX3 dyslexia susceptibility gene in Canadian families

21 January 2018

1 reference

Fine mapping of the chromosome 2p12-16 dyslexia susceptibility locus: quantitative association analysis and positional candidate genes SEMA4F and OTX1.

21 January 2018

1 reference

A genome scan for developmental dyslexia confirms linkage to chromosome 2p11 and suggests a new locus on 7q32

21 January 2018

1 reference

Fine mapping of the 2p11 dyslexia locus and exclusion of TACR1 as a candidate gene

21 January 2018

1 reference

A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia

21 January 2018

1 reference

A genome scan in multigenerational families with dyslexia: Identification of a novel locus on chromosome 2q that contributes to phonological decoding efficiency

21 January 2018

1 reference

Genomewide scan for real-word reading subphenotypes of dyslexia: novel chromosome 13 locus and genetic complexity

21 January 2018

1 reference

A dominant gene for developmental dyslexia on chromosome 3

21 January 2018

1 reference

Quantitative trait locus for reading disability on chromosome 6

21 January 2018

1 reference

Evidence for linkage and association with reading disability on 6p21.3-22.

21 January 2018

1 reference

Refinement of the 6p21.3 quantitative trait locus influencing dyslexia: linkage and association analyses

21 January 2018

1 reference

Replication of reported linkages for dyslexia and spelling and suggestive evidence for novel regions on chromosomes 4 and 17.

21 January 2018

1 reference

Evidence for linkage of spelling disability to chromosome 15

21 January 2018

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Linkage analyses of four regions previously implicated in dyslexia: confirmation of a locus on chromosome 15q.

21 January 2018

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Further evidence for a susceptibility locus contributing to reading disability on chromosome 15q15-q21.

21 January 2018

1 reference

Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study

21 January 2018

1 reference

A dyslexia susceptibility locus (DYX7) linked to dopamine D4 receptor (DRD4) region on chromosome 11p15.5.

21 January 2018

1 reference

Genetics of dyslexia: the evolving landscape

21 January 2018

1 reference

Quantitative trait locus association scan of early reading disability and ability using pooled DNA and 100K SNP microarrays in a sample of 5760 children

21 January 2018

1 reference

A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain

21 January 2018

1 reference

The complex of TFII-I, PARP1, and SFPQ proteins regulates the DYX1C1 gene implicated in neuronal migration and dyslexia

21 January 2018

1 reference

Two translocations of chromosome 15q associated with dyslexia

21 January 2018

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No support for association between dyslexia susceptibility 1 candidate 1 and developmental dyslexia

21 January 2018

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A family-based association study does not support DYX1C1 on 15q21.3 as a candidate gene in developmental dyslexia.

21 January 2018

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TDT-association analysis of EKN1 and dyslexia in a Colorado twin cohort

21 January 2018

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No evidence for association between dyslexia and DYX1C1 functional variants in a group of children and adolescents from Southern Italy

21 January 2018

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Putative functional alleles of DYX1C1 are not associated with dyslexia susceptibility in a large sample of sibling pairs from the UK

21 January 2018

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Support for EKN1 as the susceptibility locus for dyslexia on 15q21

21 January 2018

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Evaluation of candidate genes for DYX1 and DYX2 in families with dyslexia

21 January 2018

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Association of short-term memory with a variant within DYX1C1 in developmental dyslexia

21 January 2018

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Further evidence for DYX1C1 as a susceptibility factor for dyslexia

21 January 2018

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DYX1C1 functions in neuronal migration in developing neocortex

21 January 2018

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Disruption of neuronal migration by RNAi of Dyx1c1 results in neocortical and hippocampal malformations

21 January 2018

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Developmental disruptions and behavioral impairments in rats following in utero RNAi of Dyx1c1.

21 January 2018

1 reference

Molecular characterization of the DYX1C1 gene and its application as a cancer biomarker.

21 January 2018

1 reference

A novel role for DYX1C1, a chaperone protein for both Hsp70 and Hsp90, in breast cancer

21 January 2018

1 reference

Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia

21 January 2018

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Do different components of working memory underlie different subgroups of reading disabilities?

21 January 2018

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A transcription map of the 6p22.3 reading disability locus identifying candidate genes

21 January 2018

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DCDC2 is associated with reading disability and modulates neuronal development in the brain

21 January 2018

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Investigation of the DCDC2 intron 2 deletion/compound short tandem repeat polymorphism in a large German dyslexia sample

21 January 2018

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Strong genetic evidence of DCDC2 as a susceptibility gene for dyslexia

21 January 2018

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Polymorphism of DCDC2 Reveals Differences in Cortical Morphology of Healthy Individuals-A Preliminary Voxel Based Morphometry Study

21 January 2018

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The role of gene DCDC2 in German dyslexics.

21 January 2018

1 reference

Dyslexia and DCDC2: normal variation in reading and spelling is associated with DCDC2 polymorphisms in an Australian population sample

21 January 2018

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Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia

21 January 2018

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Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia

21 January 2018

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A haplotype spanning KIAA0319 and TTRAP is associated with normal variation in reading and spelling ability

21 January 2018

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Association of the KIAA0319 dyslexia susceptibility gene with reading skills in the general population.

21 January 2018

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The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration

21 January 2018

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A common variant associated with dyslexia reduces expression of the KIAA0319 gene

21 January 2018

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Investigation of interaction between DCDC2 and KIAA0319 in a large German dyslexia sample

21 January 2018

1 reference

Common and divergent roles for members of the mouse DCX superfamily

21 January 2018

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The evolving doublecortin (DCX) superfamily

21 January 2018

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Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons

21 January 2018

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Postnatal analysis of the effect of embryonic knockdown and overexpression of candidate dyslexia susceptibility gene homolog Dcdc2 in the rat

21 January 2018

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The dyslexia-associated gene KIAA0319 encodes highly N- and O-glycosylated plasma membrane and secreted isoforms

21 January 2018

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The effect of variation in expression of the candidate dyslexia susceptibility gene homolog Kiaa0319 on neuronal migration and dendritic morphology in the rat.

21 January 2018

1 reference

Alternative splicing in the dyslexia-associated gene KIAA0319

21 January 2018

1 reference

The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia

21 January 2018

1 reference

Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex

21 January 2018

1 reference

The KIAA0319-like (KIAA0319L) gene on chromosome 1p34 as a candidate for reading disabilities

21 January 2018

1 reference

Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue.

21 January 2018

1 reference

Functional skills of individuals with fragile x syndrome: a lifespan cross-sectional analysis.

21 January 2018

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Variable expression of the fragile X syndrome in heterozygous females of normal intelligence

21 January 2018

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Lifespan changes in working memory in fragile X premutation males

21 January 2018

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Fragile X mental retardation protein is required for chemically-induced long-term potentiation of the hippocampus in adult mice.

21 January 2018

1 reference

FMRP and its target RNAs: fishing for the specificity.

21 January 2018

1 reference

mRNPs, polysomes or granules: FMRP in neuronal protein synthesis

21 January 2018

1 reference

The Universal Protein Resource (UniProt) in 2010

21 January 2018

1 reference

Control of dendritic development by theDrosophila fragile X-relatedgene involves the small GTPase Rac1

21 January 2018

1 reference

Fragile x mental retardation 1 and filamin a interact genetically in Drosophila long-term memory

21 January 2018

1 reference

Localized mutations in the gene encoding the cytoskeletal protein filamin A cause diverse malformations in humans.

21 January 2018

1 reference

Periventricular heterotopia.

21 January 2018

1 reference

Like father, like son: periventricular nodular heterotopia and nonverbal learning disorder

21 January 2018

1 reference

Evidence that GRIP, a PDZ-domain protein which is expressed in the embryonic forebrain, co-activates transcription with DLX homeodomain proteins

21 January 2018

1 reference

DIP2A functions as a FSTL1 receptor

21 January 2018

1 reference

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

21 January 2018

1 reference

Identification of T-cadherin as a novel target of DNA methyltransferase 3B and its role in the suppression of nerve growth factor-mediated neurite outgrowth in PC12 cells

21 January 2018

1 reference

HDAC2 negatively regulates memory formation and synaptic plasticity.

21 January 2018

1 reference

S100B in brain damage and neurodegeneration

21 January 2018

1 reference

Glial protein S100B modulates long-term neuronal synaptic plasticity

21 January 2018

1 reference

Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia

21 January 2018

1 reference

Dock4 regulates dendritic development in hippocampal neurons

21 January 2018

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Dock4 is regulated by RhoG and promotes Rac-dependent cell migration

21 January 2018

1 reference

Learning to read in Williams syndrome: looking beneath the surface of atypical reading development

21 January 2018

1 reference

Developmental and acquired dyslexias

21 January 2018

1 reference

Neural mechanisms in Williams syndrome: a unique window to genetic influences on cognition and behaviour

21 January 2018

1 reference

Partial 7q11.23 deletions further implicate GTF2I and GTF2IRD1 as the main genes responsible for the Williams-Beuren syndrome neurocognitive profile.

21 January 2018

1 reference

A virtual reality test identifies the visuospatial strengths of adolescents with dyslexia

21 January 2018

1 reference

Fourteen new cases contribute to the characterization of the 7q11.23 microduplication syndrome

21 January 2018

1 reference

Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice

21 January 2018

1 reference

GOstat: find statistically overrepresented Gene Ontologies within a group of genes

21 January 2018

1 reference

Identification of a human homologue of the vesicle-associated membrane protein (VAMP)-associated protein of 33 kDa (VAP-33): a broadly expressed protein that binds to VAMP

21 January 2018

1 reference

A novel HSP90 chaperone complex regulates intracellular vesicle transport

21 January 2018

1 reference

Promotion of neurite extension by protrudin requires its interaction with vesicle-associated membrane protein-associated protein

21 January 2018

1 reference

Presynaptic proteins in the prefrontal cortex of patients with schizophrenia and rats with abnormal prefrontal development

21 January 2018

1 reference

Association between polymorphisms in the vesicle-associated membrane protein-associated protein A (VAPA) gene on chromosome 18p and bipolar disorder

21 January 2018

1 reference

Developmental expression of receptor for advanced glycation end products (RAGE), amphoterin and sulfoglucuronyl (HNK-1) carbohydrate in mouse cerebellum and their role in neurite outgrowth and cell migration

21 January 2018

1 reference

High mobility group B proteins facilitate strong estrogen receptor binding to classical and half-site estrogen response elements and relax binding selectivity

21 January 2018

1 reference

Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion

21 January 2018

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Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

21 January 2018

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Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway

21 January 2018

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Receptor for advanced glycation end products (RAGE) mediates neuronal differentiation and neurite outgrowth.

21 January 2018

1 reference

S100B/RAGE-dependent activation of microglia via NF-kappaB and AP-1 Co-regulation of COX-2 expression by S100B, IL-1beta and TNF-alpha

21 January 2018

1 reference

HMGB1 as an autocrine stimulus in human T98G glioblastoma cells: role in cell growth and migration

21 January 2018

1 reference

A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells

21 January 2018

1 reference

CCL2 regulates angiogenesis via activation of Ets-1 transcription factor

21 January 2018

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JAK2 activates TFII-I and regulates its interaction with extracellular signal-regulated kinase.

21 January 2018

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The activity of hsp90 alpha promoter is regulated by NF-kappa B transcription factors

21 January 2018

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NF-kappaB and AP-1 connection: mechanism of NF-kappaB-dependent regulation of AP-1 activity.

21 January 2018

1 reference

17beta-estradiol induces IL-1alpha gene expression in rheumatoid fibroblast-like synovial cells through estrogen receptor alpha (ERalpha) and augmentation of transcriptional activity of Sp1 by dissociating histone deacetylase 2 from ERalpha

21 January 2018

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Tiam1 as a signaling mediator of nerve growth factor-dependent neurite outgrowth

21 January 2018

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The calsyntenins--a family of postsynaptic membrane proteins with distinct neuronal expression patterns

21 January 2018

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Common Kibra alleles are associated with human memory performance

21 January 2018

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The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport

21 January 2018

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p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation

21 January 2018

1 reference

Chronic estradiol treatment improves brain homeostasis during aging in female rats.

21 January 2018

1 reference

Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons.

21 January 2018

1 reference

Confirmation of dyslexia susceptibility loci on chromosomes 1p and 2p, but not 6p in a Dutch sib-pair collection

21 January 2018

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Identification of novel dyslexia candidate genes through the analysis of a chromosomal deletion

21 January 2018

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Confirmation of a dyslexia susceptibility locus on chromosome 1p34-p36 in a set of 100 Canadian families

21 January 2018

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Male prevalence for reading disability is found in a large sample of black and white children free from ascertainment bias

21 January 2018

1 reference

7 January 2021

Neurobiological and experiential origins of dyslexia: an introduction

1 reference

7 January 2021

Linkage studies suggest a possible locus for developmental dyslexia on chromosome 1p

1 reference

7 January 2021

Evidence for a susceptibility locus on chromosome 6q influencing phonological coding dyslexia

1 reference

7 January 2021

Specific reading disability: identification of an inherited form through linkage analysis

1 reference

7 January 2021

Family-based association mapping provides evidence for a gene for reading disability on chromosome 15q

1 reference

7 January 2021

First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children

1 reference

7 January 2021

Dyslexia and DYX1C1: deficits in reading and spelling associated with a missense mutation

1 reference

7 January 2021

Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation

1 reference

7 January 2021

Word reading and reading‐related skills in adolescents with Williams syndrome

1 reference

7 January 2021

Molecular Mechanisms Controlling Midline Crossing by Precerebellar Neurons

1 reference

7 January 2021

The MAPK/ERK cascade targets both Elk-1 and cAMP response element-binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo.

1 reference

7 January 2021

NF-kappaB regulates netrin-1 expression and affects the conditional tumor suppressive activity of the netrin-1 receptors

1 reference

7 January 2021

Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: convergence of estrogen and neurotrophin signaling pathways.

1 reference

7 January 2021

MicroRNA-mediated switching of chromatin-remodelling complexes in neural development

1 reference

7 January 2021

Identifiers

DOI

10.1038/MP.2010.105

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31 July 2017

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