The discovery and status of sibutramine as an anti-obesity drug (Q34128195)

31 July 2017

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title

The discovery and status of sibutramine as an anti-obesity drug (English)

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31 July 2017

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Carla A Luque

1

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31 July 2017

Jose A Rey

series ordinal

2

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31 July 2017

language of work or name

English

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publication date

1 April 2002

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European Journal of Pharmacology

31 July 2017

published in

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31 July 2017

volume

440

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31 July 2017

issue

2-3

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31 July 2017

page(s)

119-128

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Long-term maintenance of weight loss after a very-low-calorie diet: a randomized blinded trial of the efficacy and tolerability of sibutramine

31 July 2017

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Sibutramine does not decrease the number of 5-HT re-uptake sites in rat brain and, like fluoxetine, protects against the deficits produced by dexfenfluramine

7 January 2021

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Sibutramine: a new weight loss agent without evidence of the abuse potential associated with amphetamines

7 January 2021

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7 January 2021

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7 January 2021

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Weight loss with sibutramine improves glycaemic control and other metabolic parameters in obese patients with type 2 diabetes mellitus

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Antidepressant treatments, including sibutramine hydrochloride and electroconvulsive shock, decrease beta 1- but not beta 2-adrenoceptors in rat cortex

7 January 2021

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Effects of antidepressant drugs and electroconvulsive shock on pre- and postsynaptic α2-adrenoceptor function in the brain: rapid down-regulation by sibutramine hydrochloride

7 January 2021

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A comparison of the effects of sibutramine hydrochloride, bupropion and methamphetamine on dopaminergic function: evidence that dopamine is not a pharmacological target for sibutramine

7 January 2021

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A comparison of various antidepressant drugs demonstrates rapid desensitisation of alpha 2-adrenoceptors exclusively by sibutramine hydrochloride

7 January 2021

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A comparison of the effects on central 5-HT function of sibutramine hydrochloride and other weight-modifying agents

7 January 2021

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Investigation of the mechanisms underlying the hypophagic effects of the 5‐HT and noradrenaline reuptake inhibitor, sibutramine, in the rat

7 January 2021

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Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat

7 January 2021

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Effect of sibutramine on weight maintenance after weight loss: a randomised trial

7 January 2021

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Comparative study of fluoxetine, sibutramine, sertraline, and dexfenfluramine on the morphology of serotonergic nerve terminals using serotonin immunohistochemistry

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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The contribution of metabolites to the rapid and potent down-regulation of rat cortical beta-adrenoceptors by the putative antidepressant sibutramine hydrochloride

7 January 2021

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Effect on radiolabelled-monoamine uptake in vitro of plasma taken from healthy volunteers administered the antidepressant sibutramine HCl

7 January 2021

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Fatal Pulmonary Hypertension Associated with Short-Term Use of Fenfluramine and Phentermine

7 January 2021

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Characterization of 8-OH-DPAT-induced hypothermia in mice as a 5-HT1A autoreceptor response and its evaluation as a model to selectively identify antidepressants

7 January 2021

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Efficacy and safety of sibutramine in obese white and African American patients with hypertension: a 1-year, double-blind, placebo-controlled, multicenter trial

7 January 2021

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7 January 2021

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7 January 2021

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Abuse liability assessment of sibutramine, a novel weight control agent

7 January 2021

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The effects of BTS 54,505, a metabolite of sibutramine, on monoamine and excitatory amino acid-evoked responses in the rat dorsolateral geniculate nucleus in vivo

7 January 2021

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Effects of sibutramine on resting metabolic rate and weight loss in overweight women

7 January 2021

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7 January 2021

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Influence of sibutramine on energy expenditure in African American women

7 January 2021

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Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors

7 January 2021

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Effects of sibutramine plus orlistat in obese women following 1 year of treatment by sibutramine alone: a placebo-controlled trial

7 January 2021

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The effect of sibutramine on resting energy expenditure and adrenaline-induced thermogenesis in obese females

7 January 2021

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10.1016/S0014-2999(02)01423-1

7 January 2021

Identifiers

DOI

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31 July 2017

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