Progeria syndromes and ageing: what is the connection? (Q34127512)

31 July 2017

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title

Progeria syndromes and ageing: what is the connection? (English)

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31 July 2017

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Christopher R Burtner

series ordinal

1

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31 July 2017

Brian K Kennedy

series ordinal

2

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31 July 2017

language of work or name

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1 August 2010

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Nature Reviews Molecular Cell Biology

31 July 2017

published in

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31 July 2017

volume

11

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31 July 2017

issue

8

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31 July 2017

page(s)

567-578

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild-type lamin A.

31 March 2020

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Perturbation of wild-type lamin A metabolism results in a progeroid phenotype

31 March 2020

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Lamin A-dependent nuclear defects in human aging

31 March 2020

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A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells

31 March 2020

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The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin

31 March 2020

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LMNA mutation in a 45 year old Japanese subject with Hutchinson-Gilford progeria syndrome.

31 March 2020

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The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein

31 March 2020

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G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment

31 March 2020

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Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein

31 March 2020

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A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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A DNA damage checkpoint response in telomere-initiated senescence

31 March 2020

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Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

31 March 2020

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Telomere length predicts replicative capacity of human fibroblasts

31 March 2020

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Telomere length in Hutchinson-Gilford progeria syndrome

31 March 2020

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Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells

31 March 2020

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The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells.

31 March 2020

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A-type lamin complexes and regenerative potential: a step towards understanding laminopathic diseases?

31 March 2020

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31 March 2020

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Lamin A/C expression is a marker of mouse and human embryonic stem cell differentiation.

31 March 2020

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Nuclear envelope defects cause stem cell dysfunction in premature-aging mice

31 March 2020

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PLEIOTROPY, NATURAL SELECTION, AND THE EVOLUTION OF SENESCENCE

31 March 2020

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31 March 2020

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Werner Syndrome, aging and cancer

31 March 2020

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Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance

31 March 2020

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DNA damage and ageing: new-age ideas for an age-old problem

31 March 2020

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31 March 2020

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Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome

31 March 2020

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Delayed and accelerated aging share common longevity assurance mechanisms

31 March 2020

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Prelamin A farnesylation and progeroid syndromes

31 March 2020

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The truncated prelamin A in Hutchinson-Gilford progeria syndrome alters segregation of A-type and B-type lamin homopolymers

31 March 2020

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Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

31 March 2020

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Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated.

31 March 2020

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Mutation spectrum of the retinoblastoma gene in osteosarcomas

31 March 2020

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12 December 2020

Differential timing of nuclear lamin A/C expression in the various organs of the mouse embryo and the young animal: a developmental study.

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12 December 2020

TOR2 Is Part of Two Related Signaling Pathways Coordinating Cell Growth in Saccharomyces cerevisiae

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12 December 2020

Osteosarcoma in a patient with Hutchinson-Gilford progeria

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12 December 2020

The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935

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12 December 2020

The evolution of ageing and longevity

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12 December 2020

Differential expression of nuclear envelope lamins A and C in human lung cancer cell lines

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12 December 2020

Nuclear A-type lamins are differentially expressed in human lung cancer subtypes

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12 December 2020

A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility

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12 December 2020

Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process

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12 December 2020

Complex formation between lamin A and the retinoblastoma gene product: identification of the domain on lamin A required for its interaction

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12 December 2020

Lamin A/C, laminopathies and premature ageing

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12 December 2020

Identifiers

DOI

10.1038/NRM2944

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Dimensions Publication ID

31 July 2017

1025973418

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