Factor IX ectopically expressed in platelets can be stored in alpha-granules and corrects the phenotype of hemophilia B mice (Q34122653)

31 July 2017

title

Factor IX ectopically expressed in platelets can be stored in alpha-granules and corrects the phenotype of hemophilia B mice (English)

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31 July 2017

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coagulation factor IX

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hemophilia B

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author name string

Guowei Zhang

1

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31 July 2017

Qizhen Shi

2

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31 July 2017

Scot A Fahs

3

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31 July 2017

Erin L Kuether

4

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31 July 2017

Christopher E Walsh

5

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31 July 2017

Robert R Montgomery

6

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31 July 2017

language of work or name

English

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publication date

5 May 2010

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31 July 2017

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31 July 2017

volume

116

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31 July 2017

issue

8

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31 July 2017

page(s)

1235-1243

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Adipose tissue is an extramedullary reservoir for functional hematopoietic stem and progenitor cells

31 July 2017

cites work

1 reference

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Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity

28 July 2018

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Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially released

28 July 2018

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Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Implantation of autologous skin fibroblast genetically modified to secrete clotting factor IX partially corrects the hemorrhagic tendencies in two hemophilia B patients

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Erythroid-specific human factor IX delivery from in vivo selected hematopoietic stem cells following nonmyeloablative conditioning in hemophilia B mice

28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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Factor VIII ectopically expressed in platelets: efficacy in hemophilia A treatment

28 October 2018

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Sustained high-level expression of human factor IX (hFIX) after liver-targeted delivery of recombinant adeno-associated virus encoding the hFIX gene in rhesus macaques

28 October 2018

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28 October 2018

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28 October 2018

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Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia

28 October 2018

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Expression of coagulation factor IX in a haematopoietic cell line

28 October 2018

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Expression of antigens of the platelet glycoprotein IIb/IIIa complex on human hematopoietic stem cells

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Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells

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Extramedullary hematopoiesis in the adult mouse liver is associated with specific hepatic sinusoidal endothelial cells

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10.1182/BLOOD-2009-11-255612

Identifiers

DOI

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31 July 2017

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31 July 2017

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