Understanding IAP function and regulation: a view from Drosophila (Q34119253)

31 July 2017

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title

Understanding IAP function and regulation: a view from Drosophila (English)

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31 July 2017

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Hay BA

1

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31 July 2017

publication date

1 November 2000

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Cell Death & Differentiation

31 July 2017

published in

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31 July 2017

volume

7

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31 July 2017

issue

11

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31 July 2017

page(s)

1045-1056

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Prevention of apoptosis by a baculovirus gene during infection of insect cells

31 July 2017

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Baculovirus-based genetic screen for antiapoptotic genes identifies a novel IAP.

21 January 2018

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The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

21 January 2018

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Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function

21 January 2018

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Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis.

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Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division

21 January 2018

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Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events

21 January 2018

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Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast.

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Control of apoptosis and mitotic spindle checkpoint by survivin

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Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

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Genetic control of programmed cell death in Drosophila

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The head involution defective gene of Drosophila melanogaster functions in programmed cell death

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grim, a novel cell death gene in Drosophila

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Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER.

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Cell killing by the Drosophila gene reaper

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An emerging blueprint for apoptosis in Drosophila

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Regulation and execution of apoptosis during Drosophila development

21 January 2018

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A fly's eye view of biology

21 January 2018

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P element insertion-dependent gene activation in the Drosophila eye.

21 January 2018

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Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

21 January 2018

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Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors

21 January 2018

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Distinct cell killing properties of the Drosophila reaper, head involution defective, and grim genes.

21 January 2018

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The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling

21 January 2018

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Anti- and pro-apoptotic activities of baculovirus and Drosophila IAPs in an insect cell line

21 January 2018

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The Drosophila inhibitor of apoptosis D-IAP1 suppresses cell death induced by the caspase drICE.

21 January 2018

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Inhibition of reaper-induced apoptosis by interaction with inhibitor of apoptosis proteins (IAPs).

21 January 2018

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Inhibitor of apoptosis proteins physically interact with and block apoptosis induced by Drosophila proteins HID and GRIM.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

A mutational analysis of the baculovirus inhibitor of apoptosis Op-IAP.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Anti-apoptotic potential of insect cellular and viral IAPs in mammalian cells.

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

21 January 2018

1 reference

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Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

21 January 2018

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Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus

21 January 2018

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Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons.

21 January 2018

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NAIP interacts with hippocalcin and protects neurons against calcium-induced cell death through caspase-3-dependent and -independent pathways

21 January 2018

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The modular nature of apoptotic signaling proteins

21 January 2018

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Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation

21 January 2018

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Structural basis for phosphoserine-proline recognition by group IV WW domains

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

A cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

The Drosophila caspase DRONC is regulated by DIAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Biochemical pathways of caspase activation during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

DRONC, an ecdysone-inducible Drosophila caspase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Baculovirus inhibitors of apoptosis (IAPs) block activation of Sf-caspase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Caspase inhibitor P35 and inhibitor of apoptosis Op-IAP block in vivo proteolytic activation of an effector caspase at different steps

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Doom, a product of the Drosophila mod(mdg4) gene, induces apoptosis and binds to baculovirus inhibitor-of-apoptosis proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Interaction of Drosophila inhibitors of apoptosis with thick veins, a type I serine/threonine kinase receptor for decapentaplegic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Apoptosis induced by Drosophila reaper and grim in a human system. Attenuation by inhibitor of apoptosis proteins (cIAPs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Ras promotes cell survival in Drosophila by downregulating hid expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Apoptotic proteins Reaper and Grim induce stable inactivation in voltage-gated K channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Reaper-induced dissociation of a Scythe-sequestered cytochrome c-releasing activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

SCF and Cullin/Ring H2-based ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Analysis of human transcriptomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Cell proliferation and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

A single BIR domain of XIAP sufficient for inhibiting caspases

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

The BIR motifs mediate dominant interference and oligomerization of inhibitor of apoptosis Op-IAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Apoptotic activity of REAPER is distinct from signaling by the tumor necrosis factor receptor 1 death domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

Isolation of an apoptosis suppressor gene of the Spodoptera littoralis nucleopolyhedrovirus

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

7 January 2021

An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

7 January 2021

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

7 January 2021

The iap genes: unique arbitrators of cell death

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https://api.crossref.org/works/10.1038/SJ.CDD.4400765

7 January 2021

S. pombe Pbh1p: an inhibitor of apoptosis domain containing protein is essential for chromosome segregation

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

7 January 2021

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

7 January 2021

Survivin' cell-separation anxiety

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

7 January 2021

Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

7 January 2021

Hormone-dependent transactivation by estrogen receptor chimeras that do not interact with hsp90. Evidence for transcriptional repressors

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4400765

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4400765

1 reference

31 July 2017

1 reference