Pharmacological characterization of a novel cannabinoid ligand, MDA19, for treatment of neuropathic pain (Q34118976)

31 July 2017

title

Pharmacological characterization of a novel cannabinoid ligand, MDA19, for treatment of neuropathic pain (English)

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31 July 2017

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Jijun J Xu

1

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31 July 2017

Philippe Diaz

2

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31 July 2017

Fanny Astruc-Diaz

3

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31 July 2017

Suzanne Craig

4

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31 July 2017

Elizandro Munoz

5

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31 July 2017

Mohamed Naguib

6

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31 July 2017

language of work or name

English

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publication date

3 June 2010

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31 July 2017

published in

Anesthesia & Analgesia

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31 July 2017

volume

111

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31 July 2017

issue

1

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31 July 2017

page(s)

99-109

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2,3-Dihydro-1-benzofuran derivatives as a series of potent selective cannabinoid receptor 2 agonists: design, synthesis, and binding mode prediction through ligand-steered modeling.

31 July 2017

cites work

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MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain models

5 July 2018

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Design and synthesis of a novel series of N-alkyl isatin acylhydrazone derivatives that act as selective cannabinoid receptor 2 agonists for the treatment of neuropathic pain

5 July 2018

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Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain

5 July 2018

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In vitro and in vivo characterization of A-796260: a selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models

5 July 2018

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Functional selectivity through protean and biased agonism: who steers the ship?

5 July 2018

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Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain

5 July 2018

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GPCR functional selectivity has therapeutic impact

5 July 2018

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Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

5 July 2018

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Species-specific in vitro pharmacological effects of the cannabinoid receptor 2 (CB2) selective ligand AM1241 and its resolved enantiomers

5 July 2018

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Protean agonism at the dopamine D2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1,Gi2, and Gi3.

5 July 2018

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Activation of peripheral cannabinoid CB1 and CB2 receptors suppresses the maintenance of inflammatory nociception: a comparative analysis

5 July 2018

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5 July 2018

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In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands.

5 July 2018

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In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB2 receptor?

5 July 2018

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Identification and functional characterization of brainstem cannabinoid CB2 receptors

5 July 2018

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Agonist-directed trafficking of response by endocannabinoids acting at CB2 receptors

5 July 2018

1 reference

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CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids

5 July 2018

1 reference

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Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors

5 July 2018

1 reference

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5 July 2018

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Basal signaling activity of mu opioid receptor in mouse brain: role in narcotic dependence

5 July 2018

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Protean agonism at histamine H3 receptors in vitro and in vivo

5 July 2018

1 reference

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Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS

5 July 2018

1 reference

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The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain

5 July 2018

1 reference

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Inverse, protean, and ligand-selective agonism: matters of receptor conformation

5 July 2018

1 reference

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Pharmacology of cannabinoid CB1 and CB2 receptors.

5 July 2018

1 reference

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The analgesic effects of R( )-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuropathic pain

5 July 2018

1 reference

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Signaling pathway associated with stimulation of CB2 peripheral cannabinoid receptor. Involvement of both mitogen-activated protein kinase and induction of Krox-24 expression

5 July 2018

1 reference

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Quantitative assessment of tactile allodynia in the rat paw

5 July 2018

1 reference

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Molecular characterization of a peripheral receptor for cannabinoids

5 July 2018

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Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors

5 July 2018

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Structure of a cannabinoid receptor and functional expression of the cloned cDNA

5 July 2018

1 reference

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An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

5 July 2018

1 reference

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Involvement of Gi in the inhibition of adenylate cyclase by cannabimimetic drugs.

5 July 2018

1 reference

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Constitutive activity of cannabinoid-2 (CB2) receptors plays an essential role in the protean agonism of ( )AM1241 and L768242.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3253719

6-Methoxy-N-alkyl isatin acylhydrazone derivatives as a novel series of potent selective cannabinoid receptor 2 inverse agonists: design, synthesis, and binding mode prediction

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3253719

CB2 cannabinoid receptor mediation of antinociception.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3253719

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3253719

A painful peripheral neuropathy in the rat produced by the chemotherapeutic drug, paclitaxel

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3253719

Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3253719

AM630 antagonism of cannabinoid-stimulated [35S]GTP gamma S binding in the mouse brain

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3253719

123I-labeled AM251: a radioiodinated ligand which binds in vivo to mouse brain cannabinoid CB1 receptors

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3253719

Protean agonism at alpha2A-adrenoceptors

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20522703

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

WIN 55,212-2 prevents mechanical allodynia but not alterations in feeding behaviour induced by chronic cisplatin in the rat

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20522703

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CB2 cannabinoid receptor-mediated peripheral antinociception

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20522703

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1213/ANE.0B013E3181E0CDAF

1 reference

31 July 2017

1 reference

31 July 2017

1 reference