Histones: Controlling Tumor Signaling Circuitry (Q34109472)

31 July 2017

title

Histones: Controlling Tumor Signaling Circuitry (English)

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31 July 2017

Manoela D Martins

1

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31 July 2017

Rogerio M Castilho

series ordinal

2

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31 July 2017

publication date

1 July 2013

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Journal of Carcinogenesis & Mutagenesis

31 July 2017

published in

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31 July 2017

volume

1

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31 July 2017

issue

Suppl 5

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31 July 2017

page(s)

1-12

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Inhibition of histone deacetylase impacts cancer stem cells and induces epithelial-mesenchyme transition of head and neck cancer

31 July 2017

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5 July 2018

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5 July 2018

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5 July 2018

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New insights into nucleosome and chromatin structure: an ordered state or a disordered affair?

5 July 2018

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SIRT1 inhibits proliferation of pancreatic cancer cells expressing pancreatic adenocarcinoma up-regulated factor (PAUF), a novel oncogene, by suppression of β-catenin

5 July 2018

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Epigenetic changes in pediatric solid tumors: promising new targets

5 July 2018

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Regulation of immune responses by histone deacetylase inhibitors

5 July 2018

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Combinatorial complexity in chromatin structure and function: revisiting the histone code

5 July 2018

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A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion

5 July 2018

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Clonal selection drives genetic divergence of metastatic medulloblastoma

5 July 2018

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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

5 July 2018

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Epigenetic-based therapies in cancer: progress to date

5 July 2018

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HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications

5 July 2018

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Preclinical evaluation of dual PI3K-mTOR inhibitors and histone deacetylase inhibitors in head and neck squamous cell carcinoma

5 July 2018

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Changes in the Histone Acetylation Patterns during the Development of the Nervous System

5 July 2018

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The dual role of sirtuins in cancer

5 July 2018

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Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

5 July 2018

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Histone deacetylases in neural stem cells and induced pluripotent stem cells

5 July 2018

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Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

5 July 2018

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The mutational landscape of head and neck squamous cell carcinoma

5 July 2018

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5 July 2018

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5 July 2018

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Cancer epigenetics reaches mainstream oncology

5 July 2018

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5 July 2018

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5 July 2018

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Regulating the regulators: the post-translational code of class I HDAC1 and HDAC2.

5 July 2018

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Interplay between SIRT proteins and tumour suppressor transcription factors in chemotherapeutic resistance of cancer

5 July 2018

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Charting histone modifications and the functional organization of mammalian genomes

5 July 2018

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Multivalent epigenetic marks confer microenvironment-responsive epigenetic plasticity to ovarian cancer cells.

5 July 2018

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PS-341 and histone deacetylase inhibitor synergistically induce apoptosis in head and neck squamous cell carcinoma cells

5 July 2018

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The role of Human papillomavirus in head and neck cancer and the impact on radiotherapy outcome

5 July 2018

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MYST family lysine acetyltransferase facilitates ataxia telangiectasia mutated (ATM) kinase-mediated DNA damage response in Toxoplasma gondii

5 July 2018

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Effects of carbon-ion radiotherapy combined with a novel histone deacetylase inhibitor, cyclic hydroxamic-acid-containing peptide 31 in human esophageal squamous cell carcinoma.

5 July 2018

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The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation.

5 July 2018

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Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T-cell lymphoma

5 July 2018

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5 July 2018

Epigenetics in cancer

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

5 July 2018

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SirT1 is an inhibitor of proliferation and tumor formation in colon cancer

5 July 2018

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HDAC2 negatively regulates memory formation and synaptic plasticity.

5 July 2018

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The role of histone deacetylases (HDACs) in human cancer

5 July 2018

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Human papillomavirus-related head and neck tumors: clinical and research implication

5 July 2018

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Linking DNA methylation and histone modification: patterns and paradigms

5 July 2018

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HDAC expression and clinical prognosis in human malignancies

5 July 2018

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Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cells

5 July 2018

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Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype

5 July 2018

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Making sense of HDAC2 mutations in colon cancer

5 July 2018

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5 July 2018

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Dysregulated molecular networks in head and neck carcinogenesis

5 July 2018

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Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity

5 July 2018

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Next-generation DNA sequencing methods

5 July 2018

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Sorafenib in lung cancer: clinical developments and future directions

5 July 2018

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The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth

5 July 2018

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Dynamic regulation of nucleosome positioning in the human genome

5 July 2018

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Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy

5 July 2018

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Histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis through both mitochondrial and Fas (Cd95) signaling in head and neck squamous carcinoma cells.

5 July 2018

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Histone deacetylase inhibitors: molecular mechanisms of action

5 July 2018

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Histone deacetylases and cancer

5 July 2018

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The MYST family of histone acetyltransferases and their intimate links to cancer.

5 July 2018

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Stability and flexibility of epigenetic gene regulation in mammalian development

5 July 2018

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Differential affinity of mammalian histone H1 somatic subtypes for DNA and chromatin.

5 July 2018

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Role for histone deacetylase 1 in human tumor cell proliferation

5 July 2018

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HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics

5 July 2018

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Antiproliferative and proapoptotic effects of histone deacetylase inhibitors on gastrointestinal neuroendocrine tumor cells

5 July 2018

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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

5 July 2018

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The molecular mechanism of HDAC inhibitors in anticancer effects

5 July 2018

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Dynamic nucleosomes and gene transcription

5 July 2018

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Polycomb complexes repress developmental regulators in murine embryonic stem cells

5 July 2018

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Epigenetic therapy of cancer: past, present and future

5 July 2018

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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

5 July 2018

1 reference

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ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Histone deacetylase inhibitors reduce VEGF production and induce growth suppression and apoptosis in human mantle cell lymphoma

5 July 2018

1 reference

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Acetylation and deacetylation of non-histone proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Core transcriptional regulatory circuitry in human embryonic stem cells

5 July 2018

1 reference

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Chromatin modifications as targets for new anticancer drugs

5 July 2018

1 reference

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Histone H1 is essential for mitotic chromosome architecture and segregation in Xenopus laevis egg extracts

5 July 2018

1 reference

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Rational development of histone deacetylase inhibitors as anticancer agents: a review

5 July 2018

1 reference

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Disruption of the gene Euchromatin Histone Methyl Transferase1 (Eu-HMTase1) is associated with the 9q34 subtelomeric deletion syndrome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

5 July 2018

1 reference

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Global cancer statistics, 2002

5 July 2018

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A method for the in vitro reconstitution of a defined "30 nm" chromatin fibre containing stoichiometric amounts of the linker histone

5 July 2018

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Histone deacetylase inhibitors

5 July 2018

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Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes

5 July 2018

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5 July 2018

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Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo

5 July 2018

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Applying the principles of stem-cell biology to cancer

5 July 2018

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A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Histone modifications: Now summoning sumoylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Histone Deacetylases: Unique Players in Shaping the Epigenetic Histone Code

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Histone deacetylase inhibitors and anticancer therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

The viral control of cellular acetylation signaling.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

A gene-expression signature as a predictor of survival in breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Cellular memory and the histone code

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Mutation analysis of CBP and PCAF reveals rare inactivating mutations in cancer cell lines but not in primary tumours

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

An increasingly complex code

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Histone deacetylase inhibitors: a new class of potential therapeutic agents for cancer treatment.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Gene expression profiling predicts clinical outcome of breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Negative control of p53 by Sir2alpha promotes cell survival under stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Translating the Histone Code

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Histone acetyltransferases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

A novel mutation lacking the bromodomain of the transcriptional coactivator p300 in the SiHa cervical carcinoma cell line

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Deacetylation of p53 modulates its effect on cell growth and apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Review: chromatin structural features and targets that regulate transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

p300 gene alterations in colorectal and gastric carcinomas.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Studies of the DNA binding properties of histone H4 amino terminus. Thermal denaturation studies reveal that acetylation markedly reduces the binding constant of the H4 "tail" to DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Histone H4 and the maintenance of genome integrity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

[A case of right adrenal myelolipoma diagnosed preoperatively and review of literature in Japan].

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

The corepressors BCOR and BCORL1: two novel players in acute myeloid leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Do all patients with head and neck cancer benefit from radiotherapy and concurrent cetuximab?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Clinical significance of histone deacetylase 1 expression in patients with hepatocellular carcinoma.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Histone acetylation increases chromatin accessibility

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Increased expression of histone deacetylase 2 is found in human gastric cancer.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

In vitro binding of H1 histone subtypes to nucleosomal organized mouse mammary tumor virus long terminal repeat promotor

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Changes in chromatin folding in solution.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

Mutations truncating the EP300 acetylase in human cancers

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4149316

28 October 2018

Epigenetics and cancer

1 reference

12 December 2020

New genes involved in cancer identified by retroviral tagging

1 reference

12 December 2020

The recommended measure

1 reference

12 December 2020

A positive role for histone acetylation in transcription factor access to nucleosomal DNA

1 reference

12 December 2020

StatBite: FDA oncology drug product approvals in 2009

1 reference

12 December 2020

[Use of key clinical symptoms in oncology for activating the educational process]

1 reference

12 December 2020

Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines

1 reference

12 December 2020

Identifiers

DOI

10.4172/2157-2518.S5-001

1 reference

31 July 2017

1 reference

31 July 2017

1 reference