Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy. (Q34103108)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812339 AND SRC:MED&resulttype=core&format=json

17 March 2020

title

Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy (English)

1 reference

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17 March 2020

0 references

1 reference

2

1 reference

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17 March 2020

Jeffrey A Kern

11

1 reference

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17 March 2020

Aik Choon Tan

14

1 reference

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17 March 2020

9

Jaewoo Kang

1 reference

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17 March 2020

6

Sonia M Leach

1 reference

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17 March 2020

Eveline Farias Hesson

7

object named as

Eveline Farias-Hesson

1 reference

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17 March 2020

3

Rangnath Mishra

1 reference

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17 March 2020

author name string

Jihye Kim

1

1 reference

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17 March 2020

Katherine R Singleton

4

1 reference

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17 March 2020

Minjae Yoo

5

1 reference

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17 March 2020

Robert J Mason

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812339 AND SRC:MED&resulttype=core&format=json

17 March 2020

Preveen Ramamoorthy

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812339 AND SRC:MED&resulttype=core&format=json

17 March 2020

Lynn E Heasley

12

1 reference

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17 March 2020

James H Finigan

13

1 reference

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17 March 2020

language of work or name

English

0 references

publication date

7 May 2014

1 reference

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17 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812339 AND SRC:MED&resulttype=core&format=json

17 March 2020

volume

30

1 reference

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17 March 2020

issue

17

1 reference

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17 March 2020

page(s)

2393-2398

1 reference

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Functional Module Connectivity Map (FMCM): a framework for searching repurposed drug compounds for systems treatment of cancer and an application to colorectal adenocarcinoma

17 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

K-Map: connecting kinases with therapeutics for drug repurposing and development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

5 July 2018

Cancer statistics, 2013

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Essential gene profiles in breast, pancreatic, and ovarian cancer cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Phase I study of bosutinib, a src/abl tyrosine kinase inhibitor, administered to patients with advanced solid tumors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Comprehensive analysis of kinase inhibitor selectivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Building disease-specific drug-protein connectivity maps from molecular interaction networks and PubMed abstracts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

sscMap: an extensible Java application for connecting small-molecule drugs using gene-expression signatures

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

A simple and robust method for connecting small-molecule drugs using gene-expression signatures

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Mapping and quantifying mammalian transcriptomes by RNA-Seq

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Differentiated human alveolar epithelial cells and reversibility of their phenotype in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

Systematic discovery of multicomponent therapeutics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147888

BiNGS!SL-seq: a bioinformatics pipeline for the analysis and interpretation of deep sequencing genome-wide synthetic lethal screen.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093/BIOINFORMATICS/BTU323

Cell cycle phenotype-based optimization of G2-abrogating peptides yields CBP501 with a unique mechanism of action at the G2 checkpoint.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093/BIOINFORMATICS/BTU323

Combining probability from independent tests: the weighted Z-method is superior to Fisher's approach

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093/BIOINFORMATICS/BTU323

A receptor tyrosine kinase network composed of fibroblast growth factor receptors, epidermal growth factor receptor, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, and hepatocyte growth factor receptor drives growth and survival of head

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24812339

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/BIOINFORMATICS/BTU323

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812339 AND SRC:MED&resulttype=core&format=json

journals/bioinformatics/KimVMSYLFMKRKHFT14

17 March 2020

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812339 AND SRC:MED&resulttype=core&format=json

17 March 2020

PubMed publication ID

24812339

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812339 AND SRC:MED&resulttype=core&format=json