Fibronectin protects from excessive liver fibrosis by modulating the availability of and responsiveness of stellate cells to active TGF-β. (Q34091329)

31 July 2017

title

Fibronectin protects from excessive liver fibrosis by modulating the availability of and responsiveness of stellate cells to active TGF-β. (English)

1 reference

31 July 2017

Nina Kawelke

1

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31 July 2017

Matthaeus Vasel

2

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31 July 2017

Carla Sens

3

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31 July 2017

Anja von Au

4

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31 July 2017

Steven Dooley

5

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31 July 2017

Inaam A Nakchbandi

6

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31 July 2017

language of work or name

English

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publication date

28 November 2011

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31 July 2017

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31 July 2017

volume

6

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31 July 2017

issue

11

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31 July 2017

page(s)

e28181

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Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

28 November 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3225392/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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1 reference

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The RGD motif in fibronectin is essential for development but dispensable for fibril assembly

28 July 2018

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Molecular mechanisms of hepatic fibrogenesis

28 July 2018

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Smad transcription factors

28 July 2018

1 reference

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Fibronectin regulates latent transforming growth factor-beta (TGF beta) by controlling matrix assembly of latent TGF beta-binding protein-1.

28 July 2018

1 reference

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SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis

28 July 2018

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28 July 2018

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Plasma fibronectin promotes thrombus growth and stability in injured arterioles

28 July 2018

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Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions

28 July 2018

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Polymerization of type I and III collagens is dependent on fibronectin and enhanced by integrins alpha 11beta 1 and alpha 2beta 1.

28 July 2018

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SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

28 July 2018

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Hepatic stellate cells: a target for the treatment of liver fibrosis

28 July 2018

1 reference

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Modulation of Cell-adhesive Activity of Fibronectin by the Alternatively Spliced EDA Segment

28 July 2018

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Inducible gene targeting in mice

28 July 2018

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The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression

28 July 2018

1 reference

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The oncofetal domain of fibronectin defined by monoclonal antibody FDC-6: its presence in fibronectins from fetal and tumor tissues and its absence in those from normal adult tissues and plasma

28 July 2018

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Apoptosis--the mechanism of cell death in dimethylnitrosamine-induced hepatotoxicity

28 July 2018

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Purification of rat hepatic stellate cells by side scatter-activated cell sorting

28 July 2018

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Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis

21 January 2018

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Emerging insights into Transforming growth factor beta Smad signal in hepatic fibrogenesis.

21 January 2018

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A major fraction of fibronectin present in the extracellular matrix of tissues is plasma-derived.

21 January 2018

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Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis

21 January 2018

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Isoform of fibronectin mediates bone loss in patients with primary biliary cirrhosis by suppressing bone formation

21 January 2018

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The EIIIA segment of fibronectin is a ligand for integrins alpha 9beta 1 and alpha 4beta 1 providing a novel mechanism for regulating cell adhesion by alternative splicing.

21 January 2018

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The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1.

21 January 2018

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Fibronectin is required for integrin alphavbeta6-mediated activation of latent TGF-beta complexes containing LTBP-1.

21 January 2018

1 reference

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Purification of fibronectin

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225392

Modeling liver fibrosis in rodents

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225392

Expression, localization and alternative splicing pattern of fibronectin messenger RNA in fibrotic human liver and hepatocellular carcinoma

28 October 2018

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12 December 2020

Gene expression and synthesis of fibronectin isoforms in rat hepatic stellate cells. comparison with liver parenchymal cells and skin fibroblasts

1 reference

12 December 2020

Alternatively spliced EDA segment regulates fibronectin-dependent cell cycle progression and mitogenic signal transduction

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12 December 2020

MMP2 activation by collagen I and concanavalin A in cultured human hepatic stellate cells

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12 December 2020

Microdetermination of hydroxyproline with chloramine-T and p-dimethylaminobenzaldehyde

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12 December 2020

Hepatic stellate cells and liver fibrosis

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12 December 2020

Circulating fibronectin isoforms predict the degree of fibrosis in chronic hepatitis C

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12 December 2020

Circulating fibronectin affects bone matrix, whereas osteoblast fibronectin modulates osteoblast function

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12 December 2020

Sample preparation method for isolation of single-cell types from mouse liver for proteomic studies

1 reference

12 December 2020

Mice lacking the EDB segment of fibronectin develop normally but exhibit reduced cell growth and fibronectin matrix assembly in vitro

1 reference

12 December 2020

Polarization microscopic studies of connective tissue stained with picro-sirius red FBA

1 reference

12 December 2020

Determination of 3- and 4-hydroxyproline

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12 December 2020

Alpha-smooth-muscle actin expression in normal and fibrotic human livers

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12 December 2020

An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

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12 December 2020

Comparison of glial fibrillary acidic protein and desmin staining in normal and CCl4-induced fibrotic rat livers

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0028181

Identifiers

DOI

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31 July 2017

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31 July 2017

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