Heterochromatin silencing of p53 target genes by a small viral protein (Q34091002)

30 July 2017

title

Heterochromatin silencing of p53 target genes by a small viral protein (English)

1 reference

30 July 2017

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Conrado Soria

1

1 reference

30 July 2017

Fanny E Estermann

series ordinal

2

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30 July 2017

Kristen C Espantman

series ordinal

3

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30 July 2017

Clodagh C O'Shea

series ordinal

4

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30 July 2017

language of work or name

English

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publication date

1 August 2010

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30 July 2017

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30 July 2017

volume

466

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30 July 2017

issue

7310

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30 July 2017

page(s)

1076-1081

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Blinded by the Light: The Growing Complexity of p53

30 July 2017

cites work

1 reference

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The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53.

28 July 2018

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Epigenetic reprogramming by adenovirus e1a.

28 July 2018

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Adenovirus small e1a alters global patterns of histone modification

28 July 2018

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Chromatin modifications and their function

28 July 2018

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The adenovirus E4 ORF3 protein binds and reorganizes the TRIM family member transcriptional intermediary factor 1 alpha

28 July 2018

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Divorcing ARF and p53: an unsettled case

28 July 2018

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Exploiting the p53 pathway for the diagnosis and therapy of human cancer.

28 July 2018

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Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus

28 July 2018

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

28 July 2018

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Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains

28 July 2018

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mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression

28 July 2018

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Cancer-specific viruses and the development of ONYX-015

28 July 2018

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Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery

28 July 2018

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Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex

28 July 2018

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Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

28 July 2018

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Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

28 July 2018

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28 July 2018

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

28 July 2018

1 reference

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Regulation of p53 in response to DNA damage

28 July 2018

1 reference

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Regulation of p53 stability by Mdm2

28 July 2018

1 reference

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An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

28 July 2018

1 reference

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Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

Definition of a consensus binding site for p53

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

T antigen is bound to a host protein in SY40-transformed cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

Viruses - seeking and destroying the tumor program

28 October 2018

1 reference

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Heat shock phenocopies E1B-55K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic viral therapy

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

p53 Functions through Stress- and Promoter-Specific Recruitment of Transcription Initiation Components before and after DNA Damage

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015).

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929938

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20740008

12 December 2020

inferred from PubMed ID database lookup

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

7 January 2021

Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents

1 reference

7 January 2021

An adenovirus type 5 early gene function regulates expression of other early viral genes

1 reference

7 January 2021

E4orf3 is necessary for enhanced S-phase replication of cell cycle-restricted subgroup C adenoviruses

1 reference

7 January 2021

Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff

1 reference

7 January 2021

Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis

1 reference

7 January 2021

The profile of repeat-associated histone lysine methylation states in the mouse epigenome

1 reference

7 January 2021

Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p53

1 reference

7 January 2021

c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism

1 reference

7 January 2021

Analysis of a multifactor microarray study using Partek genomics solution

1 reference

7 January 2021

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

1 reference

7 January 2021

Summaries of Affymetrix GeneChip probe level data

1 reference

7 January 2021

Characterizing gene sets with FuncAssociate

1 reference

7 January 2021

Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-kappaB and other signal transcription factors in head and neck squamous cell carcinoma.

1 reference

7 January 2021

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

1 reference

7 January 2021

The p53MH algorithm and its application in detecting p53-responsive genes

1 reference

7 January 2021

Identifiers

DOI

10.1038/NATURE09307

1 reference

Dimensions Publication ID

30 July 2017

0 references

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30 July 2017

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