Use of the nuclear receptor PXR to predict drug interactions (Q34088796)

30 July 2017

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title

Use of the nuclear receptor PXR to predict drug interactions (English)

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30 July 2017

Moore JT

1

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30 July 2017

Kliewer SA

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 November 2000

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30 July 2017

number of pages

10

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inferred from page(s)

published in

Toxicology

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30 July 2017

volume

153

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30 July 2017

issue

1-3

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30 July 2017

page(s)

1-10

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Steroid hormone receptors: many actors in search of a plot

30 July 2017

cites work

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7 January 2021

The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

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7 January 2021

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

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7 January 2021

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

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7 January 2021

Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes

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Newer diagnostic techniques and problems in Cushing's disease

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Identification of a new class of steroid hormone receptors

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7 January 2021

Orphan nuclear receptors: from gene to function

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7 January 2021

Cytochrome P-450 3A4: regulation and role in drug metabolism

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7 January 2021

Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control.

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7 January 2021

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

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7 January 2021

Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif

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7 January 2021

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

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7 January 2021

Substrate specificities and functions of the P450 cytochromes

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7 January 2021

Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?

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Orphan nuclear receptors: shifting endocrinology into reverse

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7 January 2021

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

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7 January 2021

Regulation of phenobarbital-inducible cytochrome P450 2B1/2 mRNA by lovastatin and oxysterols in primary cultures of adult rat hepatocytes

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7 January 2021

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

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7 January 2021

Pregnenolone-16 -carbonitrile: a new type of inducer of drug-metabolizing enzymes

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7 January 2021

The RXR heterodimers and orphan receptors

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7 January 2021

P450 genes: structure, evolution, and regulation

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The Ah locus, a multigene family necessary for survival in a chemically adverse environment: comparison with the immune system

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A novel cis-acting element in a liver cytochrome P450 3A gene confers synergistic induction by glucocorticoids plus antiglucocorticoids

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7 January 2021

Molecular mechanisms of cytochrome P-450 induction by xenobiotics: An expanded role for nuclear hormone receptors.

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7 January 2021

The influence of pregnenolone-16 -carbonitrile on hepatic mixed-function oxygenases

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7 January 2021

Use of human hepatocytes to study P450 gene induction

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7 January 2021

The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

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7 January 2021

P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

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7 January 2021

Counting the costs of drug-related adverse events

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7 January 2021

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

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7 January 2021

Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation

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7 January 2021

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Identifiers

DOI

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release_qtyldjzjwfcbzhgae7klwbz7qy

30 July 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/qtyldjzjwfcbzhgae7klwbz7qy

24 November 2022

mapped directly with Wikidata item

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