MLL associates specifically with a subset of transcriptionally active target genes (Q34078397)

30 July 2017

title

MLL associates specifically with a subset of transcriptionally active target genes (English)

1 reference

30 July 2017

Thomas A Milne

1

1 reference

ORCID Public Data File 2021

author name string

Yali Dou

2

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30 July 2017

Mary Ellen Martin

3

1 reference

30 July 2017

Hugh W Brock

4

1 reference

30 July 2017

Robert G Roeder

5

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30 July 2017

Jay L Hess

6

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30 July 2017

language of work or name

English

0 references

publication date

30 September 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

102

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30 July 2017

issue

41

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30 July 2017

page(s)

14765-14770

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WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development

30 July 2017

cites work

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Global and Hox-specific roles for the MLL1 methyltransferase

5 July 2018

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Genomic maps and comparative analysis of histone modifications in human and mouse

5 July 2018

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Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

5 July 2018

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MLL: a histone methyltransferase disrupted in leukemia

5 July 2018

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Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

A conserved non-homeodomain Hoxa9 isoform interacting with CBP is co-expressed with the 'typical' Hoxa9 protein during embryogenesis

5 July 2018

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Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization

5 July 2018

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MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein

5 July 2018

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Transcriptional elongation by RNA polymerase II and histone methylation

5 July 2018

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Regulation of elongating RNA polymerase II by forkhead transcription factors in yeast

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

MLL targets SET domain methyltransferase activity to Hox gene promoters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain

5 July 2018

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The many faces of histone lysine methylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

A homeotic mutation in the trithorax SET domain impedes histone binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

Analysis of the murine Hoxa-9 cDNA: an alternatively spliced transcript encodes a truncated protein lacking the homeodomain

5 July 2018

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11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice

5 July 2018

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Altered Hox expression and segmental identity in Mll-mutant mice

5 July 2018

1 reference

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Definitive hematopoiesis requires the mixed-lineage leukemia gene

5 July 2018

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Dimerization of MLL fusion proteins immortalizes hematopoietic cells

21 January 2018

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https://api.crossref.org/works/10.1073/PNAS.0503630102

Genomic structure and sequence analysis of human HOXA-9.

21 January 2018

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Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.

21 January 2018

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Modulation of heat shock gene expression by the TAC1 chromatin-modifying complex.

21 January 2018

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Defects in yolk sac hematopoiesis in Mll-null embryos

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253553

Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 : 11) abnormality

28 October 2018

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12 December 2020

Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny

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12 December 2020

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

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12 December 2020

Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0503630102

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference