Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis. (Q34077691)

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30 January 2020

title

Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis (English)

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2

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Christoph Kolling

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Michel Neidhart

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author name string

Astrid Jüngel

1

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Mark Lesch

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Melissa Thiel

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Teresa Sunyer

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Olivier Schorr

6

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Beat A Michel

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Renate E Gay

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Craig Flory

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Steffen Gay

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language of work or name

English

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publication date

3 June 2009

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Annals of the Rheumatic Diseases

30 January 2020

published in

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volume

69

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issue

5

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30 January 2020

page(s)

898-902

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Joint diseases and matrix metalloproteinases: a role for MMP-13.

30 January 2020

cites work

1 reference

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Cells of the synovium in rheumatoid arthritis. Synovial fibroblasts

5 July 2018

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Utility of animal models for identification of potential therapeutics for rheumatoid arthritis

5 July 2018

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Proteinases in the joint: clinical relevance of proteinases in joint destruction

5 July 2018

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MMPs as therapeutic targets--still a viable option?

5 July 2018

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Pharmacogenetics of anti-TNF treatment in patients with rheumatoid arthritis

5 July 2018

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Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects

5 July 2018

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Matrix metalloproteinases as valid clinical targets

5 July 2018

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Ten years in the life of an enzyme: the story of the human MMP-13 (collagenase-3).

5 July 2018

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Radiological damage in patients with rheumatoid arthritis on sustained remission

5 July 2018

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Mechanisms of disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis

5 July 2018

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Cartilage destruction by matrix degradation products

5 July 2018

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Prevention of progressive joint destruction in adjuvant induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR217840.

5 July 2018

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The SCID mouse model: novel therapeutic targets - lessons from gene transfer

5 July 2018

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Metalloproteinases: their role in arthritis and potential as therapeutic targets

5 July 2018

1 reference

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Characterisation of the cell type-specificity of collagenase 3 mRNA expression in comparison with membrane type 1 matrix metalloproteinase and gelatinase A in the synovial membrane in rheumatoid arthritis

5 July 2018

1 reference

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Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice

5 July 2018

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Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation

5 July 2018

1 reference

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Characterization of collagenase 3 (matrix metalloproteinase 13) messenger RNA expression in the synovial membrane and synovial fibroblasts of patients with rheumatoid arthritis

5 July 2018

1 reference

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Cloning of the gene for interstitial collagenase-3 (matrix metalloproteinase-13) from rabbit synovial fibroblasts: differential expression with collagenase-1 (matrix metalloproteinase-1)

5 July 2018

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Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice

5 July 2018

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Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage

5 July 2018

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Biochemical characterization of human collagenase-3

5 July 2018

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The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

5 July 2018

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Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue

5 July 2018

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Synovial activation of chondrocytes: Evidence for complex cytokine interactions

5 July 2018

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Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease-13: identification of a new biglycan cleavage site

5 July 2018

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Ribozymes that inhibit the production of matrix metalloproteinase 1 reduce the invasiveness of rheumatoid arthritis synovial fibroblasts

28 October 2018

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Fluorogenic MMP activity assay for plasma including MMPs complexed to alpha 2-macroglobulin

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12 December 2020

Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1)

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12 December 2020

Turnover of type II collagen and aggrecan in cartilage matrix at the onset of inflammatory arthritis in humans: Relationship to mediators of systemic and local inflammation

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12 December 2020

Collagenase-3 (MMP-13) and its activators in rheumatoid arthritis: localization in the pannus-hard tissue junction and inhibition by alendronate

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12 December 2020

Induction of collagenase-3 (MMP-13) in rheumatoid arthritis synovial fibroblasts

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12 December 2020

Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium

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12 December 2020

Identifiers

DOI

10.1136/ARD.2008.106021

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19497915 AND SRC:MED&resulttype=core&format=json

release_a42ier74ezdqxm4nwd5krhftki

30 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/a42ier74ezdqxm4nwd5krhftki

24 November 2022

mapped directly with Wikidata item

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30 January 2020

PubMed publication ID

19497915

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