Th17-related cytokines: new players in the control of chronic intestinal inflammation (Q34074137)

30 July 2017

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Th17-related cytokines: new players in the control of chronic intestinal inflammation (English)

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hemic and immune systems

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Ivan Monteleone

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30 July 2017

Francesco Pallone

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30 July 2017

Giovanni Monteleone

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30 July 2017

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15 November 2011

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https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/1741-7015-9-122

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17 December 2024

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http://link.springer.com/content/pdf/10.1186/1741-7015-9-122.pdf

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17 December 2024

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A protective function for interleukin 17A in T cell-mediated intestinal inflammation

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Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

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Late developmental plasticity in the T helper 17 lineage

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Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

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Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells

28 July 2018

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Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells.

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Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

28 July 2018

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IL-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8 T cells

28 July 2018

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Regulation of inflammatory responses by IL-17F

28 July 2018

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Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

28 July 2018

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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

28 July 2018

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IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells

28 July 2018

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28 July 2018

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28 July 2018

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IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response

28 July 2018

1 reference

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28 July 2018

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Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease

28 July 2018

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Claudins regulate the intestinal barrier in response to immune mediators

28 July 2018

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Colitis-inducing potency of CD4 T cells in immunodeficient, adoptive hosts depends on their state of activation, IL-12 responsiveness, and CD45RB surface phenotype

28 July 2018

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Disparate CD4 lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

28 July 2018

1 reference

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Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis.

28 July 2018

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Fontolizumab, a humanised anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease

21 January 2018

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Induction and effector functions of T(H)17 cells.

21 January 2018

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21 January 2018

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IL‐9 is a Th17‐derived cytokine that limits pathogenic activity in organ‐specific autoimmune disease

21 January 2018

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The role of the novel Th17 cytokine IL-26 in intestinal inflammation

21 January 2018

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Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease

21 January 2018

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The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut.

21 January 2018

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Increased expression of CCL20 in human inflammatory bowel disease

21 January 2018

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Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis

21 January 2018

1 reference

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Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals

21 January 2018

1 reference

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RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.

21 January 2018

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The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease

21 January 2018

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Regulation of gut inflammation and th17 cell response by interleukin-21.

21 January 2018

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Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells

21 January 2018

1 reference

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Over-production of IFN-gamma and IL-12 in AhR-null mice.

21 January 2018

1 reference

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Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract

21 January 2018

1 reference

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A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease

21 January 2018

1 reference

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Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration

28 October 2018

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Critical role of IL-17 receptor signaling in acute TNBS-induced colitis

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IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4 T Lymphocytes

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A Functional Role for Interleukin-21 in Promoting the Synthesis of the T-Cell Chemoattractant, MIP-3α, by Gut Epithelial Cells

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12 December 2020

Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status

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12 December 2020

Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD

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12 December 2020

Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells

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12 December 2020

Effects of aryl hydrocarbon receptor signaling on the modulation of TH1/TH2 balance

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12 December 2020

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

1 reference

12 December 2020

Human Th17 cells comprise heterogeneous subsets including IFN-gamma-producing cells with distinct properties from the Th1 lineage

1 reference

12 December 2020

Interferon-gamma-expressing cells are a major source of interleukin-21 in inflammatory bowel diseases

1 reference

12 December 2020

Journal of Clinical Investigation

52

118

534

K Sugimoto

2008

1 reference

https://api.crossref.org/works/10.1186/1741-7015-9-122

17 December 2024

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1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference