A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression (Q34073272)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20651020 AND SRC:MED&resulttype=core&format=json

8 February 2020

title

A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression (English)

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8 February 2020

0 references

1 reference

Laurens A van Meeteren

2

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8 February 2020

5

Lena Claesson-Welsh

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8 February 2020

author name string

Elena Geretti

1

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8 February 2020

Akio Shimizu

3

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8 February 2020

Andrew C Dudley

4

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8 February 2020

Michael Klagsbrun

6

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8 February 2020

publication date

22 July 2010

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Molecular Cancer Research

8 February 2020

published in

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8 February 2020

volume

8

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8 February 2020

issue

8

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8 February 2020

page(s)

1063-1073

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Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3F

8 February 2020

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Structural basis for ligand and heparin binding to neuropilin B domains

5 July 2018

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Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF/SF autocrine pathway

5 July 2018

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Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth

5 July 2018

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Functional interaction of VEGF-C and VEGF-D with neuropilin receptors

5 July 2018

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Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration

5 July 2018

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5 July 2018

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VEGF as a therapeutic target in cancer

5 July 2018

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Vascular development: from precursor cells to branched arterial and venous networks

5 July 2018

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Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype

5 July 2018

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Neuropilin-1 in human colon cancer: expression, regulation, and role in induction of angiogenesis

5 July 2018

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Discovery of semaphorin receptors, neuropilin and plexin, and their functions in neural development

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The role of neuropilin in vascular and tumor biology.

5 July 2018

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

5 July 2018

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5 July 2018

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Neuropilin-1 binds vascular endothelial growth factor 165, placenta growth factor-2, and heparin via its b1b2 domain

5 July 2018

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VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Neuropilin Is a Receptor for the Axonal Chemorepellent Semaphorin III

5 July 2018

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Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver

5 July 2018

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Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1.

28 October 2018

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28 October 2018

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Tuftsin binds neuropilin-1 through a sequence similar to that encoded by exon 8 of vascular endothelial growth factor

28 October 2018

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28 October 2018

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A requirement for neuropilin-1 in embryonic vessel formation.

28 October 2018

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Characterization of a Bicyclic Peptide Neuropilin-1 (NP-1) Antagonist (EG3287) Reveals Importance of Vascular Endothelial Growth Factor Exon 8 for NP-1 Binding and Role of NP-1 in KDR Signaling

28 October 2018

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12 December 2020

Site-directed mutagenesis in the B-neuropilin-2 domain selectively enhances its affinity to VEGF165, but not to semaphorin 3F

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12 December 2020

VEGF receptor signal transduction

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12 December 2020

Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165

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12 December 2020

10.1158/1541-7786.MCR-10-0157

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20651020 AND SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20651020 AND SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

20651020

1 reference