The apoptotic pathway: a target for therapy in chronic lymphocytic leukemia (Q34057963)

30 July 2017

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title

The apoptotic pathway: a target for therapy in chronic lymphocytic leukemia (English)

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chronic lymphocytic leukemia

30 July 2017

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Bentley DP

1

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30 July 2017

Pepper CJ

series ordinal

2

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30 July 2017

publication date

1 September 2000

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30 July 2017

published in

Hematological Oncology

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30 July 2017

volume

18

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30 July 2017

issue

3

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30 July 2017

page(s)

87-98

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https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

30 July 2017

1 reference

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Bax directly induces release of cytochrome c from isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Programmed cell death: the influence of CD40, CD95 (Fas or Apo-I) and their ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

21 January 2018

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

IARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

A peptide sequence from Bax that converts Bcl-2 into an activator of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Channel formation by antiapoptotic protein Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Gene transfer of CD40-ligand induces autologous immune recognition of chronic lymphocytic leukemia B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

p53 as a target for anti-cancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

The inhibition of DNA synthesis in chronic lymphocytic leukaemia cells by chlorambucil in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Cytogenetic mapping of the duplicated segment of chromosome 12 in lymphoproliferative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Two functional assays employed to detect an unusual mutation in the oligomerisation domain of p53 in a Li-Fraumeni like family

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Elevated levels of biologically active soluble CD40 ligand in the serum of patients with chronic lymphocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Quantitative characterization and potential function of membrane Fas/APO‐1 (CD95) receptors on leukaemic cells from chronic B and T lymphoid leukaemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Downregulation of the CD95 receptor and defect CD40-mediated signal transduction in B-chronic lymphocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Regulation of clinical chemoresistance by bcl-2 and bax oncoproteins in B-cell chronic lymphocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Chlorambucil resistance in B-cell chronic lymphocytic leukaemia is mediated through failed Bax induction and selection of high Bcl-2-expressing subclones

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Drug-induced apoptosis in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Processing/activation of caspases, -3 and -7 and -8 but not caspase-2, in the induction of apoptosis in B-chronic lymphocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

Antisense-mediated suppression of Bcl-2 highlights its pivotal role in failed apoptosis in B-cell chronic lymphocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

BCL-2 antisense therapy in patients with non-Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

10.1002/1099-1069(200009)18:3<87::AID-HON661>3.0.CO;2-8

21 January 2018

Identifiers

DOI

1 reference

30 July 2017

1 reference