Mesenchymal stem cells restore frataxin expression and increase hydrogen peroxide scavenging enzymes in Friedreich ataxia fibroblasts (Q34053510)

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15 January 2020

title

Mesenchymal stem cells restore frataxin expression and increase hydrogen peroxide scavenging enzymes in Friedreich ataxia fibroblasts (English)

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15 January 2020

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mesenchymal stem cell

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1

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15 January 2020

Neil Scolding

5

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15 January 2020

author name string

Elizabeth Mallam

2

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15 January 2020

Kelly Hares

3

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15 January 2020

Jonathan Witherick

4

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15 January 2020

Alastair Wilkins

6

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language of work or name

English

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publication date

7 October 2011

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15 January 2020

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volume

6

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issue

10

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page(s)

e26098

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Creative Commons Attribution 4.0 International

15 January 2020

copyright license

start time

7 October 2011

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April 2022 Public Data File from Crossref

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copyrighted

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ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3189234/fullTextXML

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cites work

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Deferiprone targets aconitase: implication for Friedreich's ataxia treatment

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HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model

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Hydrogen peroxide scavenging rescues frataxin deficiency in a Drosophila model of Friedreich's ataxia

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Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity

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28 July 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Frataxin promotes antioxidant defense in a thiol-dependent manner resulting in diminished malignant transformation in vitro

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Glutathione in blood of patients with Friedreich's ataxia.

21 January 2018

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Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells

21 January 2018

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Human mesenchymal stem cells abrogate experimental allergic encephalomyelitis after intraperitoneal injection, and with sparse CNS infiltration

21 January 2018

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Human mesenchymal stem cells infiltrate the spinal cord, reduce demyelination, and localize to white matter lesions in experimental autoimmune encephalomyelitis.

21 January 2018

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Neuroprotection and immunomodulation with mesenchymal stem cells in chronic experimental autoimmune encephalomyelitis

21 January 2018

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Intravenous infusion of bone marrow mesenchymal stem cells improves myocardial function in a rat model of myocardial ischemia

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Effects of Erythropoietin on Frataxin Levels and Mitochondrial Function in Friedreich Ataxia – a Dose–Response Trial

21 January 2018

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SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction

21 January 2018

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12 December 2020

Epoetin alfa increases frataxin production in Friedreich's ataxia without affecting hematocrit

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12 December 2020

Disabled early recruitment of antioxidant defenses in Friedreich's ataxia

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12 December 2020

Recombinant human erythropoietin increases frataxin protein expression without increasing mRNA expression

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10.1371/JOURNAL.PONE.0026098

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22016819 AND SRC:MED&resulttype=core&format=json

15 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22016819 AND SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

22016819

1 reference