High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes (Q34050186)

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14 January 2020

title

High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes (English)

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14 January 2020

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1

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14 January 2020

Zhenfeng Duan

7

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14 January 2020

author name string

Francis Hornicek

2

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14 January 2020

Laura MacConaill

3

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14 January 2020

David Harmon

4

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14 January 2020

Zeeshan Tariq

5

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14 January 2020

Levi Garraway

6

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14 January 2020

language of work or name

English

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publication date

17 October 2011

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14 January 2020

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14 January 2020

volume

118

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14 January 2020

issue

11

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14 January 2020

page(s)

2905-2914

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Osteosarcoma: a review of diagnosis, management, and treatment strategies

14 January 2020

cites work

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Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

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Rapamycin pharmacokinetic and pharmacodynamic relationships in osteosarcoma: a comparative oncology study in dogs

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Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway

28 July 2018

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Development of phosphoinositide-3 kinase pathway inhibitors for advanced cancer

28 July 2018

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Lentiviral shRNA screen of human kinases identifies PLK1 as a potential therapeutic target for osteosarcoma

28 July 2018

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Activation of signal transducer and activator of transcription 3 (Stat3) pathway in osteosarcoma cells and overexpression of phosphorylated-Stat3 correlates with poor prognosis.

28 July 2018

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Profiling critical cancer gene mutations in clinical tumor samples

28 July 2018

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Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines.

28 July 2018

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Novel therapeutic agents for osteosarcoma

28 July 2018

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Therapy for osteosarcoma: where do we go from here?

28 July 2018

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Lentiviral short hairpin RNA screen of genes associated with multidrug resistance identifies PRP-4 as a new regulator of chemoresistance in human ovarian cancer

28 July 2018

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Major response to imatinib mesylate in KIT-mutated melanoma.

28 July 2018

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Epidermal growth factor receptor in osteosarcoma: expression and mutational analysis

28 July 2018

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The consensus coding sequences of human breast and colorectal cancers

28 July 2018

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Chemotherapy resistance in osteosarcoma: current challenges and future directions.

28 July 2018

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Survival data for 648 patients with osteosarcoma treated at one institution

28 July 2018

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Genome-wide array comparative genomic hybridization analysis reveals distinct amplifications in osteosarcoma

28 July 2018

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Biology and therapeutic advances for pediatric osteosarcoma

28 July 2018

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

28 July 2018

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Frequent amplification and rearrangement of chromosomal bands 6p12-p21 and 17p11.2 in osteosarcoma

28 July 2018

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PI3K/PTEN/AKT pathway. A critical mediator of oncogenic signaling

28 July 2018

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R1507, a fully human monoclonal antibody targeting IGF-1R, is effective alone and in combination with rapamycin in inhibiting growth of osteosarcoma xenografts

21 January 2018

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28 October 2018

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Targeted therapy of human osteosarcoma with 17AAG or rapamycin: characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways.

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28 October 2018

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21 January 2018

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12 December 2020

Osteosarcoma: clinical practice and the expanding role of biology

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12 December 2020

Loss of imprinting of IGF2 and H19 in osteosarcoma is accompanied by reciprocal methylation changes of a CTCF-binding site

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12 December 2020

Experimental therapies and clinical trials in bone sarcoma

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12 December 2020

Adjuvant chemotherapy for osteosarcoma: a decade of experience

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12 December 2020

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12 December 2020

Comprehensive mapping of p53 pathway alterations reveals an apparent role for both SNP309 and MDM2 amplification in sarcomagenesis

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12 December 2020

Loss of heterozygosity of the RB gene is a poor prognostic factor in patients with osteosarcoma

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12 December 2020

Mechanisms of methotrexate resistance in osteosarcoma

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12 December 2020

Identifiers

DOI

10.1002/CNCR.26617

1 reference

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14 January 2020

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14 January 2020

PubMed publication ID

22006429

1 reference