Interaction of picrotoxin with GABAA receptor channel-lining residues probed in cysteine mutants. (Q34047528)

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15 October 2019

title

Interaction of picrotoxin with GABAA receptor channel-lining residues probed in cysteine mutants (English)

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15 October 2019

3

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15 October 2019

author name string

M Xu

series ordinal

1

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15 October 2019

D F Covey

series ordinal

2

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15 October 2019

language of work or name

English

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publication date

1 November 1995

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15 October 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8580329 AND SRC:MED&resulttype=core&format=json

15 October 2019

volume

69

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15 October 2019

issue

5

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15 October 2019

page(s)

1858-1867

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LOCALIZATION OF ERYTHROCYTE MEMBRANE SULFHYDRYL GROUPS ESSENTIAL FOR GLUCOSE TRANSPORT.

15 October 2019

cites work

1 reference

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A point mutation in a Drosophila GABA receptor confers insecticide resistance.

5 July 2018

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Structure of nicotinic acetylcholine receptors

5 July 2018

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Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons

5 July 2018

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A single-amino acid substitution in a gamma-aminobutyric acid subtype A receptor locus is associated with cyclodiene insecticide resistance in Drosophila populations

5 July 2018

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Selective effects of dieldrin on the GABAA receptor-channel subunits expressed in human embryonic kidney cells

5 July 2018

1 reference

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Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans

5 July 2018

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A unique amino acid of the Drosophila GABA receptor with influence on drug sensitivity by two mechanisms

5 July 2018

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5 July 2018

GABAA receptor channels

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GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital

5 July 2018

1 reference

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Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family

5 July 2018

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Dissociation of [35S]t-butylbicyclophosphorothionate binding differentiates convulsant and depressant drugs that modulate GABAergic transmission

5 July 2018

1 reference

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A novel alpha subunit in rat brain GABAA receptors

5 July 2018

1 reference

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Two novel GABAA receptor subunits exist in distinct neuronal subpopulations

5 July 2018

1 reference

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GABAA receptor beta subunit heterogeneity: functional expression of cloned cDNAs

5 July 2018

1 reference

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Blockade of gamma-aminobutyric acid-gated chloride current in frog sensory neurons by picrotoxin.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones

5 July 2018

1 reference

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Molecular biology of GABAA receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Synthesis and structure-activity studies of alkyl-substituted .gamma.-butyrolactones and .gamma.-thiobutyrolactones: ligands for the picrotoxin receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Mutations in M2 alter the selectivity of the mouse nicotinic acetylcholine receptor for organic and alkali metal cations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Acetylcholine receptor channel structure probed in cysteine-substitution mutants.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

GABAA receptor channels: from subunits to functional entities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Kinetic properties of alpha 1 beta 1 gamma-aminobutyric acidA receptor channels expressed in Chinese hamster ovary cells: regulation by pentobarbital and picrotoxin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Kinetics of open channel block by penicillin of single GABAA receptor channels from mouse spinal cord neurones in culture

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

On the mechanism of action of picrotoxin on GABA receptor channels in dissociated sympathetic neurones of the rat.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Binding of [3H]alpha-dihydropicrotoxinin, a gamma-aminobutyric acid synaptic antagonist, to rat brain membranes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Point mutations in the M2 region of the alpha, beta, or gamma subunit of the GABAA channel that abolish block by picrotoxin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Identification of a residue in the translocation pathway of a membrane carrier.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

How quickly can GABAA receptors open?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Amino acids lining the channel of the gamma-aminobutyric acid type A receptor identified by cysteine substitution

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1236419

Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates

28 October 2018

1 reference

12 December 2020

Acetylcholine receptor channel imaged in the open state

1 reference

12 December 2020

Pentobarbital and picrotoxin have reciprocal actions on single GABAA receptor channels

1 reference

12 December 2020

Gamma-butyrolactone antagonism of the picrotoxin receptor: comparison of a pure antagonist and a mixed antagonist/inverse agonist

1 reference

12 December 2020

Location of a threonine residue in the α -subunit M2 transmembrane segment that determines the ion flow through the acetylcholine receptor channel

1 reference

12 December 2020

Nicotinic acetylcholine receptor at 9 A resolution.

1 reference

12 December 2020

[35S]t-butylbicyclophosphorothionate binds with high affinity to brain-specific sites coupled to gamma-aminobutyric acid-A and ion recognition sites

1 reference

12 December 2020

10.1016/S0006-3495(95)80056-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8580329 AND SRC:MED&resulttype=core&format=json

15 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8580329 AND SRC:MED&resulttype=core&format=json

15 October 2019

PubMed publication ID

8580329

1 reference