β-Agonist-mediated relaxation of airway smooth muscle is protein kinase A-dependent. (Q34044729)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24973219 AND SRC:MED&resulttype=core&format=json

21 March 2020

title

β-Agonist-mediated relaxation of airway smooth muscle is protein kinase A-dependent (English)

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21 March 2020

9

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21 March 2020

8

Reynold A Panettieri

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21 March 2020

2

Deepak A Deshpande

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21 March 2020

author name string

Sarah J Morgan

1

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21 March 2020

Brian C Tiegs

3

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21 March 2020

Anna M Misior

4

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21 March 2020

Huandong Yan

5

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21 March 2020

Alena V Hershfeld

6

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21 March 2020

Thomas C Rich

7

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21 March 2020

Raymond B Penn

10

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21 March 2020

language of work or name

English

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publication date

27 June 2014

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Journal of Biological Chemistry

21 March 2020

published in

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21 March 2020

volume

289

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21 March 2020

issue

33

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21 March 2020

page(s)

23065-23074

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The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH

21 March 2020

cites work

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The cAMP-responsive Rap1 guanine nucleotide exchange factor, Epac, induces smooth muscle relaxation by down-regulation of RhoA activity

28 July 2018

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Protein kinase A and the exchange protein directly activated by cAMP (Epac) modulate phenotype plasticity in human airway smooth muscle

28 July 2018

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28 July 2018

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Anti-mitogenic effects of β-agonists and PGE2 on airway smooth muscle are PKA dependent.

28 July 2018

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cAMP inhibits modulation of airway smooth muscle phenotype via the exchange protein activated by cAMP (Epac) and protein kinase A

28 July 2018

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Epac as a novel effector of airway smooth muscle relaxation

28 July 2018

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The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function

28 July 2018

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The small heat shock-related protein, HSP20, is a cAMP-dependent protein kinase substrate that is involved in airway smooth muscle relaxation.

28 July 2018

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Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors

28 July 2018

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Targeting G protein-coupled receptor signaling in asthma

28 July 2018

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Meta-analysis: effect of long-acting beta-agonists on severe asthma exacerbations and asthma-related deaths

28 July 2018

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Do biophysical properties of the airway smooth muscle in culture predict airway hyperresponsiveness?

28 July 2018

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Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling

28 July 2018

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28 July 2018

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Evidence that the anti-spasmogenic effect of the beta-adrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase

28 July 2018

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Molecular mechanism of cGMP-mediated smooth muscle relaxation

28 July 2018

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cAMP-dependent vasodilators cross-activate the cGMP-dependent protein kinase to stimulate BK(Ca) channel activity in coronary artery smooth muscle cells

28 July 2018

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Activation of KCa channels in airway smooth muscle cells by endogenous protein kinase A.

28 July 2018

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cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets

28 July 2018

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Beta-adrenergic agonists regulate KCa channels in airway smooth muscle by cAMP-dependent and -independent mechanisms

28 July 2018

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28 July 2018

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Subsensitivity of bronchodilator and systemic beta 2 adrenoceptor responses after regular twice daily treatment with eformoterol dry powder in asthmatic patients

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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Cooperative regulation of p70S6 kinase by receptor tyrosine kinases and G protein-coupled receptors augments airway smooth muscle growth

28 October 2018

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Cytokines regulate beta-2-adrenergic receptor responsiveness in airway smooth muscle via multiple PKA- and EP2 receptor-dependent mechanisms

28 October 2018

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Extracellular matrix modulates beta2-adrenergic receptor signaling in human airway smooth muscle cells

28 October 2018

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Ligand-mediated activation of the cAMP-responsive guanine nucleotide exchange factor Epac

28 October 2018

1 reference

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Signaling and regulation of G protein-coupled receptors in airway smooth muscle

28 October 2018

1 reference

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Scaling the microrheology of living cells

28 October 2018

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The beta-agonist saga and its clinical relevance: on and on it goes

28 October 2018

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12 December 2020

Elevated lung G protein levels and muscarinic receptor affinity in a mouse model of airway hyperreactivity

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12 December 2020

Bronchodilator subsensitivity after chronic dosing with eformoterol in patients with asthma

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12 December 2020

End of the New Zealand asthma mortality epidemic

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12 December 2020

Bronchodilator subsensitivity to salbutamol after twice daily salmeterol in asthmatic patients

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12 December 2020

Pharmacological inhibition of protein kinases in intact cells: antagonism of beta adrenergic receptor ligand binding by H-89 reveals limitations of usefulness

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12 December 2020

Cooperative mitogenic signaling by G protein-coupled receptors and growth factors is dependent on G(q/11)

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12 December 2020

Mitogenic effects of cytokines on smooth muscle are critically dependent on protein kinase A and are unmasked by steroids and cyclooxygenase inhibitors

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12 December 2020

Identifiers

DOI

10.1074/JBC.M114.557652

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24973219 AND SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24973219 AND SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

24973219

1 reference