Regulated necrosis: the expanding network of non-apoptotic cell death pathways. (Q34039639)

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6 March 2020

title

Regulated necrosis: the expanding network of non-apoptotic cell death pathways (English)

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6 March 2020

Andreas Linkermann

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6 March 2020

Sandrine Jouan-Lanhouet

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6 March 2020

Peter Vandenabeele

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6 March 2020

author name string

Henning Walczak

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6 March 2020

publication date

1 February 2014

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Nature Reviews Molecular Cell Biology

6 March 2020

published in

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volume

15

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issue

2

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page(s)

135-147

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Programmed cell death—II. Endocrine potentiation of the breakdown of the intersegmental muscles of silkmoths

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Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase

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Structure-activity relationship study of a novel necroptosis inhibitor, necrostatin-7

31 March 2020

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A novel necroptosis inhibitor-necrostatin-21 and its SAR study

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Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.

31 March 2020

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Membrane-bound Fas ligand requires RIP1 for efficient activation of caspase-8 within the death-inducing signaling complex

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Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features.

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Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease

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Attenuation of brain edema and spatial learning deﬁcits by the inhibition of NADPH oxidase activity using apocynin following diffuse traumatic brain injury in rats

31 March 2020

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NADPH oxidases in heart failure: poachers or gamekeepers?

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Riboflavin kinase couples TNF receptor 1 to NADPH oxidase

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Recognition of bacteria by inflammasomes

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31 March 2020

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Salmonella induces macrophage death by caspase-1-dependent necrosis

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

31 March 2020

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cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

31 March 2020

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Antigen-mediated T cell expansion regulated by parallel pathways of death

31 March 2020

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Poly IC triggers a cathepsin D- and IPS-1-dependent pathway to enhance cytokine production and mediate dendritic cell necroptosis.

31 March 2020

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Shikonin circumvents cancer drug resistance by induction of a necroptotic death

31 March 2020

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Shikonin kills glioma cells through necroptosis mediated by RIP-1

31 March 2020

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Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes

31 March 2020

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Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases

31 March 2020

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PKR; a sentinel kinase for cellular stress

31 March 2020

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Necrotic death pathway in Fas receptor signaling

31 March 2020

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RIP3 mediates the embryonic lethality of caspase-8-deficient mice

31 March 2020

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

31 March 2020

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FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

31 March 2020

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Functional complementation between FADD and RIP1 in embryos and lymphocytes

31 March 2020

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Survival function of the FADD-CASPASE-8-cFLIP(L) complex

31 March 2020

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Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice

31 March 2020

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The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore

31 March 2020

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Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis

31 March 2020

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Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration

31 March 2020

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Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury

31 March 2020

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The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

31 March 2020

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Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

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RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome

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Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

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Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis.

31 March 2020

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12 December 2020

Primate neurons show different vulnerability to transient ischemia and response to cathepsin inhibition

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Cell death: multitasking p53 promotes necrosis

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Sphingosine-induced apoptosis is dependent on lysosomal proteases

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Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation

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Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model

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12 December 2020

Mitochondrial permeability transition and cell death: the role of cyclophilin d

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12 December 2020

Quinolinic Acid, an endogenous molecule combining excitotoxicity, oxidative stress and other toxic mechanisms

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12 December 2020