Repression of androgen receptor transcription through the E2F1/DNMT1 axis (Q34038056)

30 July 2017

title

Repression of androgen receptor transcription through the E2F1/DNMT1 axis (English)

1 reference

30 July 2017

David G Johnson

7

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author name string

Conrad David Valdez

1

1 reference

30 July 2017

Joanne N Davis

2

1 reference

30 July 2017

Hana M Odeh

3

1 reference

30 July 2017

Tristan L Layfield

4

1 reference

30 July 2017

Craig S Cousineau

5

1 reference

30 July 2017

Thomas R Berton

6

1 reference

30 July 2017

Kirk J Wojno

8

1 reference

30 July 2017

Mark L Day

9

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30 July 2017

language of work or name

English

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publication date

26 September 2011

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30 July 2017

1 reference

30 July 2017

volume

6

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30 July 2017

issue

9

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30 July 2017

page(s)

e25187

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

26 September 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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The E2F family and the role of E2F1 in apoptosis

5 July 2018

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Establishment of a novel immortalized human prostatic epithelial cell line stably expressing androgen receptor and its application for the functional screening of androgen receptor modulators.

5 July 2018

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MeCP2 knockdown reveals DNA methylation-independent gene repression of target genes in living cells and a bias in the cellular location of target gene products.

5 July 2018

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5 July 2018

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Cyclical DNA methylation of a transcriptionally active promoter

5 July 2018

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Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor

5 July 2018

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Functional cooperation between HP1 and DNMT1 mediates gene silencing.

5 July 2018

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hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site

5 July 2018

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Molecular analysis and characterization of PrEC, commercially available prostate epithelial cells

5 July 2018

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The Polycomb group protein EZH2 directly controls DNA methylation

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

E2Fs link the control of G1/S and G2/M transcription

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

DNA methyltransferase 1 knock down induces gene expression by a mechanism independent of DNA methylation and histone deacetylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Methylation analysis of the glypican 3 gene in embryonal tumours

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Rescue of embryonic epithelium reveals that the homozygous deletion of the retinoblastoma gene confers growth factor independence and immortality but does not influence epithelial differentiation or tissue morphogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

The human p73 promoter: characterization and identification of functional E2F binding sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Gene expression changes in response to E2F1 activation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Direct repression of the Mcl-1 promoter by E2F1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Sibling rivalry in the E2F family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

E2F-1 represses transcription of the human telomerase reverse transcriptase gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Androgen-driven prostate epithelial cell proliferation and differentiation in vivo involve the regulation of p27.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Role for the p53 homologue p73 in E2F-1-induced apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Pocket protein-independent repression of urokinase-type plasminogen activator and plasminogen activator inhibitor 1 gene expression by E2F1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Negative regulation of the androgen receptor gene promoter by NFI and an adjacently located multiprotein-binding site

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Differential induction of the androgen receptor transcriptional activity by selective androgen receptor coactivators.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor gamma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Activation of the murine dihydrofolate reductase promoter by E2F1. A requirement for CBP recruitment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

p14ARF links the tumour suppressors RB and p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Steroid receptor interactions with heat shock protein and immunophilin chaperones

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

E2F-1 but not E2F-4 can overcome p16-induced G1 cell-cycle arrest

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Two different, overlapping pathways of transcription initiation are active on the TATA-less human androgen receptor promoter. The role of Sp1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Androgen-induced inhibition of cell proliferation in an androgen-insensitive prostate cancer cell line (PC-3) transfected with a human androgen receptor complementary DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

A novel regulatory element associated with age-dependent expression of the rat androgen receptor gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Identification and characterization of a suppressor element in the 5'-flanking region of the mouse androgen receptor gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Oncogenic capacity of the E2F1 gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Regulation of androgen action by receptor gene inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Analysis of cell death and cell proliferation in embryonic stages, normal adult, and aging prostates in human and animals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Sequences 5' of the bovine keratin 5 gene direct tissue- and cell-type-specific expression of a lacZ gene in the adult and during development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Expression of the human androgen receptor gene utilizes a common promoter in diverse human tissues and cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Characterization of the human androgen receptor transcription unit

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Anti-androgens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Normal and abnormal development of the male urogenital tract. Role of androgens, mesenchymal-epithelial interactions, and growth factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

The paradox of E2F1: oncogene and tumor suppressor gene.

5 July 2018

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https://api.crossref.org/works/10.1371/JOURNAL.PONE.0025187

Regulation of BRCA1 expression by the Rb-E2F pathway.

21 January 2018

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https://api.crossref.org/works/10.1371/JOURNAL.PONE.0025187

Elevated E2F1 inhibits transcription of the androgen receptor in metastatic hormone-resistant prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0025187

Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines.

21 January 2018

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https://api.crossref.org/works/10.1371/JOURNAL.PONE.0025187

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

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https://api.crossref.org/works/10.1371/JOURNAL.PONE.0025187

Methyl-CpG-binding domain protein-2 mediates transcriptional repression associated with hypermethylated GSTP1 CpG islands in MCF-7 breast cancer cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

The androgen receptor: a mediator of diverse responses.

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180375

Androgen-Independent Prostate Cancer Is a Heterogeneous Group of Diseases

29 October 2018

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https://api.crossref.org/works/10.1371/JOURNAL.PONE.0025187

Androgen receptor status of lymph node metastases from prostate cancer

21 January 2018

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12 December 2020

Modular organization of the E2F1 activation domain and its interaction with general transcription factors TBP and TFIIH

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12 December 2020

Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development

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12 December 2020

Toward an understanding of the functional complexity of the E2F and retinoblastoma families

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12 December 2020

Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells

1 reference

12 December 2020

Methylation of the androgen receptor minimal promoter silences transcription in human prostate cancer

1 reference

12 December 2020

Autoregulation of androgen receptor expression in rodent prostate: immunohistochemical and in situ hybridization analysis

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0025187

Identifiers

DOI

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30 July 2017

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30 July 2017

1 reference