Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life (Q34035703)

30 July 2017

title

Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life (English)

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30 July 2017

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ChEBI release 2020-05-28

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Jeremie Guedj

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Alan S. Perelson

9

object named as

Alan S Perelson

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30 July 2017

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Harel Dahari

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30 July 2017

Libin Rong

3

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30 July 2017

Natasha D Sansone

4

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30 July 2017

Richard E Nettles

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30 July 2017

Scott J Cotler

6

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30 July 2017

Thomas J Layden

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30 July 2017

Susan L Uprichard

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30 July 2017

language of work or name

English

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publication date

19 February 2013

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

110

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30 July 2017

issue

10

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30 July 2017

page(s)

3991-3996

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Preliminary study of two antiviral agents for hepatitis C genotype 1.

30 July 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Small molecules targeting hepatitis C virus-encoded NS5A cause subcellular redistribution of their target: insights into compound modes of action

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Second-phase hepatitis C virus RNA decline during telaprevir-based therapy increases with drug effectiveness: implications for treatment duration.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Protease Inhibitor–Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

All three domains of the hepatitis C virus nonstructural NS5A protein contribute to RNA binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Modeling Subgenomic Hepatitis C Virus RNA Kinetics during Treatment with Alpha Interferon

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Interaction of Hepatitis C Virus Nonstructural Protein 5A with Core Protein Is Critical for the Production of Infectious Virus Particles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Regulation of Hepatitis C Virion Production via Phosphorylation of the NS5A Protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Identification of Residues Required for RNA Replication in Domains II and III of the Hepatitis C Virus NS5A Protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

The prevalence of hepatitis C virus infection in the United States, 1999 through 2002

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Quantitative Analysis of the Hepatitis C Virus Replication Complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Hepatitis C virus NS5A: tales of a promiscuous protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Viral and Cellular Determinants of Hepatitis C Virus RNA Replication in Cell Culture

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Effect of alpha interferon on the hepatitis C virus replicon

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Efficient initiation of HCV RNA replication in cell culture

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Rapid production and clearance of HIV-1 and hepatitis C virus assessed by large volume plasma apheresis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

Domain III of NS5A contributes to both RNA replication and assembly of hepatitis C virus particles

5 July 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1203110110

A comprehensive hepatitis C viral kinetic model explaining cure

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1203110110

Kinetics of hepatitis C virus reinfection after liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1203110110

Second hepatitis C replication compartment indicated by viral dynamics during liver transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.1203110110

Rapid decrease of wild-type hepatitis C virus on telaprevir treatment.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3593898

29 October 2018

Identifiers

DOI

10.1073/PNAS.1203110110

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30 July 2017

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30 July 2017

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