Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition. (Q34035076)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074 AND SRC:MED&resulttype=core&format=json

22 February 2020

review article

1 reference

title

Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074 AND SRC:MED&resulttype=core&format=json

22 February 2020

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074 AND SRC:MED&resulttype=core&format=json

22 February 2020

Christopher B Marshall

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074 AND SRC:MED&resulttype=core&format=json

22 February 2020

Mitsuhiko Ikura

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074 AND SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Feng Wang

1

1 reference

30 July 2017

Christopher B Marshall

2

1 reference

30 July 2017

Mitsuhiko Ikura

3

1 reference

30 July 2017

publication date

11 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074 AND SRC:MED&resulttype=core&format=json

Cellular and Molecular Life Sciences

22 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074 AND SRC:MED&resulttype=core&format=json

22 February 2020

volume

70

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074 AND SRC:MED&resulttype=core&format=json

22 February 2020

issue

21

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22 February 2020

page(s)

3989-4008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074 AND SRC:MED&resulttype=core&format=json

Transcriptional coactivators in yeast and beyond

22 February 2020

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Conformational selection or induced fit: a flux description of reaction mechanism

21 January 2018

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The nuclear receptor ligand-binding domain: structure and function

21 January 2018

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A signature motif in transcriptional co-activators mediates binding to nuclear receptors

21 January 2018

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Intrinsically unstructured proteins and their functions

21 January 2018

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Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation

21 January 2018

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Structural and functional characterization of an atypical activation domain in erythroid Kruppel-like factor (EKLF)

21 January 2018

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Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53

21 January 2018

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Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a

21 January 2018

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The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.

21 January 2018

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Modulation of STAT signaling by STAT-interacting proteins

21 January 2018

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Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

21 January 2018

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Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers

21 January 2018

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21 January 2018

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1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Differential activation of CREB by Ca2 /calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Modulation of p300 binding by posttranslational modifications of the C-terminal activation domain of hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

A novel mechanism for cyclic adenosine 3',5'-monophosphate regulation of gene expression by CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

CREB binding protein recruitment to the transcription complex requires growth factor-dependent phosphorylation of its GF box.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

A peek into the complex realm of histone phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Epigenetic regulation by histone methylation and histone variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Histone ubiquitination: triggering gene activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Histone sumoylation is associated with transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Functions of site-specific histone acetylation and deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Chromatin remodeling and cancer, Part I: Covalent histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Histone acetylation increases chromatin accessibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

CBP/p300-mediated acetylation of histone H3 on lysine 56

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Structure and chemistry of the p300/CBP and Rtt109 histone acetyltransferases: implications for histone acetyltransferase evolution and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

A novel Rb- and p300-binding protein inhibits transactivation by MyoD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Synergistic activation of transcription by CBP and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Regulation of FoxO activity by CBP/p300-mediated acetylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Broad thumbs and toes and facial abnormalities. A possible mental retardation syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Rubinstein-Taybi syndrome caused by a De Novo reciprocal translocation t(2;16)(q36.3;p13.3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Systematic in vivo structure-function analysis of p300 in hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

MOZ is fused to p300 in an acute monocytic leukemia with t(8;22).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Selective roles for cAMP response element-binding protein binding protein and p300 protein as coregulators for androgen-regulated gene expression in advanced prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Targeted Inhibition of β-Catenin/CBP Signaling Ameliorates Renal Interstitial Fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

The Gamma Catenin/CBP Complex Maintains Survivin Transcription in &#946;-catenin Deficient/Depleted Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Pancreas duodenum homeobox-1 transcriptional activation requires interactions with p300

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Quantitative control of adaptive cardiac hypertrophy by acetyltransferase p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Transcriptional switches: chemical approaches to gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

21 January 2018

The targets of curcumin.

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Specific inhibition of p300-HAT alters global gene expression and represses HIV replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Mechanism of p300 specific histone acetyltransferase inhibition by small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

The bromodomain interaction module

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Histone recognition and large-scale structural analysis of the human bromodomain family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Interplay of bromodomain and histone acetylation in the regulation of p300-dependent genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Direct inhibition of hypoxia-inducible transcription factor complex with designed dimeric epidithiodiketopiperazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Identification of small-molecule antagonists that inhibit an activator: coactivator interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Discovery of a small-molecule inhibitor of the KIX-KID interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Amphipathic small molecules mimic the binding mode and function of endogenous transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

The LxxLL motif: a multifunctional binding sequence in transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00018-012-1254-4

Mapping acetylation sites in E2A identifies a conserved lysine residue in activation domain 1 that promotes CBP/p300 recruitment and transcriptional activation.

21 January 2018

1 reference

12 December 2020

CREB-binding protein activates transcription through multiple domains

1 reference

12 December 2020

Characterization of an E1A-CBP interaction defines a novel transcriptional adapter motif (TRAM) in CBP/p300

1 reference

12 December 2020

CBP-induced stimulation of c-Fos activity is abrogated by E1A.

1 reference

12 December 2020

Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II

1 reference

12 December 2020

CBP as a transcriptional coactivator of c-Myb

1 reference

12 December 2020

Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP

1 reference

12 December 2020

The t(11;16)(q23;p13) translocation in myelodysplastic syndrome fuses the MLL gene to the CBP gene

1 reference

12 December 2020

E2A proteins enhance the histone acetyltransferase activity of the transcriptional co-activators CBP and p300

1 reference

12 December 2020

Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP.

1 reference

12 December 2020

Acetylation of cAMP-responsive element-binding protein (CREB) by CREB-binding protein enhances CREB-dependent transcription

1 reference

12 December 2020

Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro

1 reference

12 December 2020

All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders

1 reference

12 December 2020

p300 mediates cellular resistance to doxorubicin in bladder cancer.

1 reference

12 December 2020

Phosphorylation of p53 serine 15 increases interaction with CBP

1 reference

12 December 2020

Phosphorylation-induced transient intrinsic structure in the kinase-inducible domain of CREB facilitates its recognition by the KIX domain of CBP

1 reference

12 December 2020

Protein dynamics and conformational disorder in molecular recognition

1 reference

12 December 2020

p300 in prostate cancer proliferation and progression.

1 reference

12 December 2020

Variation in microdeletions of the cyclic AMP-responsive element-binding protein gene at chromosome band 16p13.3 in the Rubinstein-Taybi syndrome

1 reference

12 December 2020

CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein

1 reference

12 December 2020

Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines

1 reference

12 December 2020

NovelMLL-CBP fusion transcript in therapy-related chronic myelomonocytic leukemia with a t(11;16) (q23;p13) chromosome translocation

1 reference

12 December 2020

10.1007/S00018-012-1254-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23307074 AND SRC:MED&resulttype=core&format=json

22 February 2020

1 reference