Targeting immune co-stimulatory effects of PD-L1 and PD-L2 might represent an effective therapeutic strategy in stroke. (Q34024724)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25157219 AND SRC:MED&resulttype=core&format=json

13 March 2020

title

Targeting immune co-stimulatory effects of PD-L1 and PD-L2 might represent an effective therapeutic strategy in stroke (English)

1 reference

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13 March 2020

author name string

Sheetal Bodhankar

1

1 reference

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13 March 2020

Yingxin Chen

2

1 reference

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13 March 2020

Arthur A Vandenbark

4

1 reference

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13 March 2020

Stephanie J Murphy

5

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13 March 2020

publication date

11 August 2014

1 reference

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Frontiers in Cellular Neuroscience

13 March 2020

published in

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13 March 2020

volume

8

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13 March 2020

page(s)

228

1 reference

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Treatment of experimental stroke with IL-10-producing B-cells reduces infarct size and peripheral and CNS inflammation in wild-type B-cell-sufficient mice

13 March 2020

cites work

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PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1.

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Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

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Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2

5 July 2018

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5 July 2018

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A regulatory B cell subset with a unique CD1dhiCD5 phenotype controls T cell-dependent inflammatory responses

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5 July 2018

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Induction of immunologic tolerance to myelin basic protein prevents central nervous system autoimmunity and improves outcome after stroke

5 July 2018

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5 July 2018

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5 July 2018

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Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses

5 July 2018

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T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammation

5 July 2018

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Tissue expression of PD-L1 mediates peripheral T cell tolerance.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Immunologic tolerance to myelin basic protein decreases stroke size after transient focal cerebral ischemia

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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21 January 2018

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Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues.

21 January 2018

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21 January 2018

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Regulation of PD‐1, PD‐L1, and PD‐L2 expression during normal and autoimmune responses

21 January 2018

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Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury

21 January 2018

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Oestrogen-mediated protection of experimental autoimmune encephalomyelitis in the absence of Foxp3 regulatory T cells implicates compensatory pathways including regulatory B cells

21 January 2018

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B7-H1 and CD8 Treg: the enigmatic role of B7-H1 in peripheral tolerance

21 January 2018

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Role of T lymphocytes and interferon-gamma in ischemic stroke

21 January 2018

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PD-L2 expression extends beyond dendritic cells/macrophages to B1 cells enriched for V(H)11/V(H)12 and phosphatidylcholine binding.

21 January 2018

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https://api.crossref.org/works/10.3389/FNCEL.2014.00228

CTLA-4 Overexpression Inhibits T Cell Responses through a CD28-B7-Dependent Mechanism

21 January 2018

2 references

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21 January 2018

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Human muscle cells express a B7-related molecule, B7-H1, with strong negative immune regulatory potential: a novel mechanism of counterbalancing the immune attack in idiopathic inflammatory myopathies

29 October 2018

1 reference

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Differential role of programmed death-ligand 1 [corrected] and programmed death-ligand 2 [corrected] in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25157219

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PD-L1 and PD-L2 have distinct roles in regulating host immunity to cutaneous leishmaniasis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25157219

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Experimental stroke induces massive, rapid activation of the peripheral immune system

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25157219

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FNCEL.2014.00228

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25157219 AND SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25157219 AND SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

25157219

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25157219 AND SRC:MED&resulttype=core&format=json