Structural basis for the positional specificity of lipoxygenases (Q34017581)

30 July 2017

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title

Structural basis for the positional specificity of lipoxygenases (English)

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30 July 2017

Kuhn H

1

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30 July 2017

publication date

1 August 2000

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Prostaglandins and Other Lipid Mediators

30 July 2017

published in

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30 July 2017

volume

62

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30 July 2017

issue

3

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30 July 2017

page(s)

255-270

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The 5-lipoxygenase and leukotriene forming enzymes

30 July 2017

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A lipoxygenase in rabbit reticulocytes which attacks phospholipids and intact mitochondria

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Arachidonate 12-lipoxygenase

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The diversity of the lipoxygenase family. Many sequence data but little information on biological significance

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Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate

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cDNA cloning, genomic structure, and chromosomal localization of a novel murine epidermis-type lipoxygenase

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Soybean lipoxygenase-1 enzymically forms both (9S)- and (13S)-hydroperoxides from linoleic acid by a pH-dependent mechanism.

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7 January 2021

Change in the positional specificity of lipoxygenase 1 due to insertion of fatty acids into phosphatidylcholine deoxycholate mixed micelles

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7 January 2021

Probing the substrate alignment at the active site of 15-lipoxygenases by targeted substrate modification and site-directed mutagenesis. Evidence for an inverse substrate orientation.

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Cloning and characterization of a murine macrophage lipoxygenase

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Murine epidermal lipoxygenase (Aloxe) encodes a 12-lipoxygenase isoform

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Human 12(R)-lipoxygenase and the mouse ortholog. Molecular cloning, expression, and gene chromosomal assignment

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A 12R-lipoxygenase in human skin: mechanistic evidence, molecular cloning, and expression

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Discovery of a second 15S-lipoxygenase in humans

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Molecular Cloning and Functional Expression of a Phorbol Ester-inducible 8S-Lipoxygenase from Mouse Skin

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Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase

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C-11 H-abstraction from linoieic acid, the rate-limiting step in lipoxygenase catalysis

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Mechanism of biosynthesis of 11R-and 12R-hydroxyeicosatetraenoic acids by eggs of the sea urchin Strongylocentrotus purpuratus

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Purification and molecular cloning of an 8R-lipoxygenase from the coral Plexaura homomalla reveal the related primary structures of R- and S-lipoxygenases

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Discovery of 5R-lipoxygenase activity in oocytes of the surf clam, Spisula solidissima

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7 January 2021

Nature of hydrogen transfer in soybean lipoxygenase 1: separation of primary and secondary isotope effects

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7 January 2021

Evidence for a lipoxygenase mechanism in the biosynthesis of epoxide and dihydroxy leukotrienes from 15(S)-hydroperoxyicosatetraenoic acid by human platelets and porcine leukocytes

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7 January 2021

The three-dimensional structure of an arachidonic acid 15-lipoxygenase

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7 January 2021

Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution

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7 January 2021

The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity

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7 January 2021

Arachidonate lipoxygenase in blood platelets

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7 January 2021

Double dioxygenation of arachidonic acid by soybean lipoxygenase-1. Kinetics and regio-stereo specificities of the reaction steps

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7 January 2021

A primary determinant for lipoxygenase positional specificity

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7 January 2021

Conversion of human 15-lipoxygenase to an efficient 12-lipoxygenase: the side-chain geometry of amino acids 417 and 418 determine positional specificity.

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7 January 2021

Rat 12-lipoxygenase: mutations of amino acids implicated in the positional specificity of 15- and 12-lipoxygenases

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7 January 2021

Phenylalanine 353 is a primary determinant for the positional specificity of mammalian 15-lipoxygenases

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7 January 2021

Shape and specificity in mammalian 15-lipoxygenase active site. The functional interplay of sequence determinants for the reaction specificity.

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7 January 2021

Conversion of cucumber linoleate 13-lipoxygenase to a 9-lipoxygenating species by site-directed mutagenesis

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7 January 2021

Defining the arachidonic acid binding site of human 15-lipoxygenase. Molecular modeling and mutagenesis

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7 January 2021

A molecular dipstick?

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7 January 2021

Relation between positional specificity and chirality in mammalian lipoxygenases.

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7 January 2021

Omega-oxidation impairs oxidizability of polyenoic fatty acids by 15-lipoxygenases: consequences for substrate orientation at the active site

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7 January 2021

Expression of lipoxygenase in wounded tubers of Solanum tuberosum L.

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7 January 2021

Site-directed mutagenesis studies on the iron-binding domain and the determinant for the substrate oxygenation site of porcine leukocyte arachidonate 12-lipoxygenase.

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7 January 2021

Simultaneous expression of leukocyte-type 12-lipoxygenase and reticulocyte-type 15-lipoxygenase in rabbits

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7 January 2021

Identification of amino acid determinants of the positional specificity of mouse 8S-lipoxygenase and human 15S-lipoxygenase-2

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7 January 2021

10.1016/S0090-6980(00)00084-8

Identifiers

DOI

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30 July 2017

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