Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model. (Q33996719)

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29 January 2020

title

Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model (English)

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4

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Peter Henry St George-Hyslop

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16

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author name string

JoAnne McLaurin

1

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Meredith E Kierstead

2

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29 January 2020

Mary E Brown

3

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29 January 2020

Mark H L Lambermon

5

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Amie L Phinney

6

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Audrey A Darabie

7

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Julian E Cousins

8

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Janet E French

9

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Melissa F Lan

10

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Fusheng Chen

11

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Sydney S N Wong

12

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Howard T J Mount

13

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Paul E Fraser

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David Westaway

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language of work or name

English

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publication date

11 June 2006

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volume

12

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issue

7

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page(s)

801-808

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Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease

29 January 2020

cites work

1 reference

Membrane disruption by Alzheimer beta-amyloid peptides mediated through specific binding to either phospholipids or gangliosides. Implications for neurotoxicity.

21 January 2018

1 reference

Characterization of the interactions of Alzheimer beta-amyloid peptides with phospholipid membranes.

21 January 2018

1 reference

Accelerated accumulation of amyloid beta proteins on oxidatively damaged lipid membranes

21 January 2018

1 reference

Cholesterol-dependent Generation of a Seeding Amyloid β-Protein in Cell Culture

21 January 2018

1 reference

The interaction between Alzheimer amyloid beta(1-40) peptide and ganglioside GM1-containing membranes

21 January 2018

1 reference

GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease.

21 January 2018

1 reference

Predicting the energetics of osmolyte-induced protein folding/unfolding.

21 January 2018

1 reference

Inositol stereoisomers stabilize an oligomeric aggregate of Alzheimer amyloid beta peptide and inhibit abeta -induced toxicity.

21 January 2018

1 reference

Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

21 January 2018

1 reference

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

21 January 2018

1 reference

Developments of a water-maze procedure for studying spatial learning in the rat

21 January 2018

1 reference

Abeta toxicity in Alzheimer's disease: globular oligomers (ADDLs) as new vaccine and drug targets

21 January 2018

1 reference

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

1 reference

Myo-inositol transport through the blood-brain barrier.

21 January 2018

1 reference

Identification of a mammalian H( )-myo-inositol symporter expressed predominantly in the brain

21 January 2018

1 reference

The SLC2 family of facilitated hexose and polyol transporters

21 January 2018

1 reference

Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis.

21 January 2018

1 reference

Immunization against Alzheimer's beta -amyloid plaques via EFRH phage administration

21 January 2018

1 reference

Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology

21 January 2018

1 reference

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

21 January 2018

1 reference

Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease

21 January 2018

1 reference

Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease

21 January 2018

1 reference

A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

1 reference

Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance

21 January 2018

1 reference

Object recognition memory and cholinergic parameters in mice expressing human presenilin 1 transgenes

21 January 2018

1 reference

Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation.

21 January 2018

1 reference

Carboxyl-terminal fragments of Alzheimer beta-amyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells.

21 January 2018

1 reference

No hippocampal neuron or synaptic bouton loss in learning-impaired aged beta-amyloid precursor protein-null mice

21 January 2018

1 reference

The impact of Aβ-plaques on cortical cholinergic and non-cholinergic presynaptic boutons in alzheimer's disease-like transgenic mice

21 January 2018

1 reference

Amyloid accumulation and pathogensis of Alzheimer's disease: significance of monomeric, oligomeric and fibrillar Abeta.

21 January 2018

1 reference

7 January 2021

Phosphatidylinositol and inositol involvement in Alzheimer amyloid-beta fibril growth and arrest

1 reference

7 January 2021

Assay of myo-inositol in cerebrospinal fluid and plasma by chemical ionization mass spectrometry of the hexaacetate derivative

1 reference

7 January 2021

Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia.

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7 January 2021